The catecholamines, in particular norepinephrine and epinephrine, are targets of the G protein-coupled receptor class known as adrenergic receptors. These receptors are found on numerous cells, and when a catecholamine binds to one of these receptors, the sympathetic nervous system is typically stimulated. The fight-or-flight response is controlled by the sympathetic nervous system, which causes the eye pupils to dilate, the body to mobilize energy, and the blood supply to skeletal muscle to be diverted from non-essential organs.There are numerous subtypes of the two main groups of adrenergic receptors, and. The receptor subtypes 1 and 2 exist. There are three subtypes of receptors: 1, 2, and 3. They are all associated with Gs proteins, which are associated with adenylate cyclase. Thus, antagonist binding increases the level of the second messenger cAMP inside of the cell. The cAMP-dependent protein kinase (PKA), one of cAMP's downstream effectors, mediates some intracellular processes after hormone binding.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V71347 | (+)-Sotalol ((S)-Sotalol) | 30236-32-9 | (+)-Sotalol ((S)-Sotalol) is the S-isomer of Sotalol. |
|
V71260 | (-)-Scopolamine (Atroscine) | 138-12-5 | (-)-Scopolamine (Atroscine) is an isomer of Scopolamine. |
|
V71318 | (Des-His6)-ACTH (1-24) (human, bovine, rat) | 1926163-11-2 | (Des-His6)-ACTH (1-24) (human, bovine, rat) is an analog of adrenocorticotropic hormone (ACTH). |
|
V71238 | (R)-(+)-Atenolol | 56715-13-0 | (R)-(+)-Atenolol is the less active enantiomer of (R,S)-atenolol. |
|
V79234 | (R)-9-Hydroxy Risperidone-d4 | (R)-9-Hydroxy Risperidone-d4 is the deuterium labelled form of (R)-9-Hydroxy Risperidone. | |
|
V71303 | (R)-Metoprolol-d7 (Metoprolol d7) | 1292907-84-6 | (R)-Metoprolol-d7 is the deuterium labelled form of Metoprolol. |
|
V40138 | (R)-Carvedilol | 95093-99-5 | (R)-Carvedilol is an optically active and R-enantiomer of Carvedilol, which is a nonselective ß-adrenergic blocker with a1-blocking activity. |
|
V70516 | (R,R)-Reboxetine mesylate ((R,R)-FCE20124 mesylate; (R,R)-PNU155950E mesylate) | 105017-39-8 | (R,R)-Reboxetine mesylate is an antidepressant with good bioavailability. |
|
V71297 | (rac)-Dobutamine-d4 hydrochloride | 1246815-74-6 | (rac)-Dobutamine-d4 ( HCl) is the deuterated racemate of Dobutamine HCl. |
|
V71323 | (rac)-Dobutamine-d6 hydrochloride | 1246818-96-1 | (rac)-Dobutamine-d6 ( HCl) is the deuterated racemate of Dobutamine HCl. |
|
V71355 | (rac)-Nebivolol-d4 (Nebivolol-d4) | 1219407-55-2 | (rac)-Nebivolol-d4 is the deuterated racemate of Nebivolol. |
|
V71312 | (Rac)-Talinolol-d5 | 1215343-94-4 | (Rac)-Talinolol-d5 is the racemic deuterated form of Talinolol. |
|
V71276 | (Rac)-ICI-118551 hydrochloride | 1217094-53-5 | (Rac)-Zenidolol (ICI-118551) HCl is a selective beta2-adrenergic receptor antagonist. |
|
V71345 | (RS)-Butyryltimolol | 2320274-78-8 | (RS)-Butyryltimolol is the racemate of Butyryltimolol. |
|
V71344 | (S)-(-)-Propranolol hydrochloride ((S)-(-)-Propranolol hydrochloride) | 4199-10-4 | (S)-(-)-Propranolol HCl is an adrenergic receptor (β-adrenergic receptor) antagonist (inhibitor) with log Kds of -8.16, -9.08 and -6.93 for β1, β2, and β3 respectively. |
|
V71267 | (S)-Metoprolol-d7 (Metoprolol d7) | 1292906-91-2 | (S)-Metoprolol-d7 is the deuterium labelled form of Metoprolol. |
|
V37874 | (S)-Terazosin | 109351-33-9 | S)-Terazosin is the S-enantiomer of Terazosin,which is a selective α1-adrenoceptor antagonist used for treatment of symptoms of BPH (benign prostatic hyperplasia, an enlarged prostate). |
|
V71313 | (±)-N-Methylcolaurine | 1472-62-4 | (±)-N-Methylcolaurine is a selective α2-adrenergic receptor blocker (antagonist). |
|
V71279 | (±)-Penbutolol-d9 hydrochloride ((Rac)-Penbutolol-d9 (hydrochloride); (±)-Isopenbutolol-d9 (hydrochloride)) | 1346605-01-3 | (±)-Penbutolol-d9 (HCl) is a deuterium-labeled (±)-Penbutolol HCl. |
|
V71237 | 2-Methoxyidazoxan monohydrochloride (RX821002 hydrochloride) | 109544-45-8 | 2-Methoxyidazoxan mono HCl (RX821002 HCl) is a selective alpha 2r adrenergic receptor antagonist (inhibitor) with little or no antagonism to imidazoline. |
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