One of the most deadly pathogens for primates is the filovirus. Lethal hemorrhagic fever is brought on by filoviruses in both humans and nonhuman primates. Marburgvirus, which includes different strains of the Lake Victoria marburgvirus (MARV), and Ebolavirus (EBOVs), which includes four species including Sudan ebolavirus (SEBOV), Zaire ebolavirus (ZEBOV), Ivory Coast ebolavirus (CIEBOV), and Reston ebolavirus (REBOV), as well as a tentative species Bundibugyo ebolavirus (BEBOV).
The infections typically spread throughout the body's organs and are frequently accompanied by bleeding. The virus can then spread from person to person after being transferred from an animal host to a human.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V52513 | 2'-Deoxy-5'-O-DMT-2'-fluorouridine | 146954-74-7 | 2'-Deoxy-5'-O-DMT-2'-fluorouridine is a nucleoside analog and an analogue of 5'-O-DMTr-5-FUDR. |
|
V88245 | Antiviral agent 12 | 314030-54-1 | Antiviral agent 12 is an antiviral compound. |
|
V2280 | ASN03576800 | 957513-35-8 | ASN03576800 may be a potent inhibitor of Ebola virus matrix protein VP40 during virus assembly and budding. |
|
V54249 | Cephaeline hydrochloride ((-)-Cephaeline hydrochloride; NSC 32944 monohydrochloride) | 3738-70-3 | Cephaeline HCl ((-)-Cephaeline HCl) is a phenolic alkaloid in Indian Ipecac. |
|
V2224 | Ebola and Marburg Entry Inhibitor | 2479465-67-1 | Ebola and Marburg Entry Inhibitor, a 4-(aminomethyl)benzamide-based compound, is a novel and potent entry inhibitor of Ebola and Marburg rirus infections. |
|
V54170 | EBOV-IN-1 | 1335113-30-8 | EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor (blocker/antagonist) of Ebola virus (EBOV). |
|
V88241 | EBOV-IN-2 | EBOV-IN-2 (Compound 2) is an Ebola virus (EBOV) inhibitor with IC50 values of 0.37 μM and 2.54 μM against Ebola virus glycoprotein pseudotyped virus (pEBOV) and African swine fever virus (ASFV), respectively. | |
|
V88237 | EBOV-IN-3 | EBOV-IN-3 (compound 9) is a benzothiazepine compound. | |
|
V88242 | EBOV-IN-4 | EBOV-IN-4 (compound 12) is a benzothiazepine-type drug and a potent Ebola virus (EBOV) inhibitor with an inhibition rate of 64.9% against EBOV-GP pseudotyped virus (pEBOV) at 10 μM. EBOV-IN-4 is inactive against ASFV. | |
|
V88240 | EBOV-IN-6 | EBOV-IN-6 (compound 19) is a benzothiazepine compound. EBOV-IN-6 has anti-pEBOV activity with IC50 of 10 μM. | |
|
V88238 | EBOV-IN-7 | EBOV-IN-7 (compound 26) is an inhibitor of EBOV with an IC50 of 2.04 μM against EBOV-GP pseudotyped virus (pEBOV). | |
|
V88239 | EBOV-IN-8 | EBOV-IN-8 (Compound 30) inhibits Ebola pseudotyped virus (pEBOV) infection (IC50=62.1% 10 μM). | |
|
V88243 | EBOV-IN-9 | EBOV-IN-9 (compound 2b) is a diphyllin derivative that blocks Ebola virus entry with an EC50 of 40 nM. | |
|
V54169 | EBOV/MARV-IN-3 | 2687245-05-0 | EBOV/MARV-IN-3 (compound 32) is a potent inhibitor of EBOV and MARV with IC50s of 0.5 and 1.2 µM respectively. |
|
V52075 | FX-06 (Fibrin-derived peptide Bβ15-42) | 88650-17-3 | FX-06 (Fibrin-derived peptide Bβ15-42) is a fibrin Bbeta chain-derived peptide. |
|
V88244 | pEBOV-IN-1 | 1252187-41-9 | pEBOV-IN-1 (Comp 2) is an inhibitor of pEBOV with EC50 of 0.38 μM. |
|
V2432 | Retro 2 | 1201652-50-7 | Retro-2 is a selective inhibitor of endosomal protein-Golgi retrograde transport. |
|
V51947 | Sinococuline | 109351-36-2 | Sinococuline is a potent anti-dengue virus agent, active against all four dengue virus (DENV) serotypes. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
