One of the most deadly pathogens for primates is the filovirus. Lethal hemorrhagic fever is brought on by filoviruses in both humans and nonhuman primates. Marburgvirus, which includes different strains of the Lake Victoria marburgvirus (MARV), and Ebolavirus (EBOVs), which includes four species including Sudan ebolavirus (SEBOV), Zaire ebolavirus (ZEBOV), Ivory Coast ebolavirus (CIEBOV), and Reston ebolavirus (REBOV), as well as a tentative species Bundibugyo ebolavirus (BEBOV).
The infections typically spread throughout the body's organs and are frequently accompanied by bleeding. The virus can then spread from person to person after being transferred from an animal host to a human.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V52513 | 2'-Deoxy-5'-O-DMT-2'-fluorouridine | 146954-74-7 | 2'-Deoxy-5'-O-DMT-2'-fluorouridine is a nucleoside analog and an analogue of 5'-O-DMTr-5-FUDR. |
|
V52414 | Ansuvimab (Ansuvimab-zyk; mAb114) | 2375952-29-5 | Ansuvimab (Ansuvimab-zyk) is a recombinant human monoclonal IgG1 antibody with antiviral effect against Zaire Ebola virus. |
|
V2280 | ASN03576800 | 957513-35-8 | ASN03576800 may be a potent inhibitor of Ebola virus matrix protein VP40 during virus assembly and budding. |
|
V54165 | Atoltivimab (REGN3470) | 2135632-29-8 | Atoltivimab (REGN3470) and maftivimab/odesivimab (Inmazeb) are the first monoclonal antibodies approved by the U.S. Food and Drug Administration (FDA) for Zaire Ebola virus (EBOV) infection. |
|
V54249 | Cephaeline hydrochloride ((-)-Cephaeline hydrochloride; NSC 32944 monohydrochloride) | 3738-70-3 | Cephaeline HCl ((-)-Cephaeline HCl) is a phenolic alkaloid in Indian Ipecac. |
|
V54167 | Cosfroviximab (c13C6-FR1) | 1792982-57-0 | Cosfroviximab (c13C6-FR1) is a mouse/human chimeric monoclonal antibody (mAb) against Ebola virus glycoprotein (EBOV-GP). |
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V2224 | Ebola and Marburg Entry Inhibitor | 2479465-67-1 | Ebola and Marburg Entry Inhibitor, a 4-(aminomethyl)benzamide-based compound, is a novel and potent entry inhibitor of Ebola and Marburg rirus infections. |
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V54170 | EBOV-IN-1 | 1335113-30-8 | EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor (blocker/antagonist) of Ebola virus (EBOV). |
|
V54169 | EBOV/MARV-IN-3 | 2687245-05-0 | EBOV/MARV-IN-3 (compound 32) is a potent inhibitor of EBOV and MARV with IC50s of 0.5 and 1.2 µM respectively. |
|
V52075 | FX-06 (Fibrin-derived peptide Bβ15-42) | 88650-17-3 | FX-06 (Fibrin-derived peptide Bβ15-42) is a fibrin Bbeta chain-derived peptide. |
|
V54171 | Larcaviximab (c4G7-N) | 1792982-56-9 | Larcaviximab (c4G7-N) is an IgG1 kappa anti-Ebola virus glycoprotein chimeric monoclonal antibody (mAb). |
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V54172 | Maftivimab (REGN3470-3471-3479) | 2135632-36-7 | Maftivimab (REGN3470-3471-3479) is a Filovirus inhibitor and is a Food and Drug Administration (FDA)-approved agent. |
|
V54248 | porgaviximab | 1792982-55-8 | Porgaviximab is a monoclonal antibody (mAb) used to study Ebola virus infection. |
|
V2432 | Retro 2 | 1201652-50-7 | Retro-2 is a selective inhibitor of endosomal protein-Golgi retrograde transport. |
|
V51947 | Sinococuline | 109351-36-2 | Sinococuline is a potent anti-dengue virus agent, active against all four dengue virus (DENV) serotypes. |
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