The acetylcholine receptors known as mAChRs (muscarinic acetylcholine receptors) are found in the cell membranes of some neurons and other cells. The primary end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system is one of their many functions. Because they are more sensitive to muscarine than to nicotine, mAChRs are so named. Nicotinic acetylcholine receptors (nAChRs), receptor ion channels that are also significant in the autonomic nervous system, are their counterparts. Numerous medications and other substances, such as scopolamine and pilocarpine, act as selective agonists or antagonists on these two different receptors. The brain and the autonomic ganglia are both rich sources of the neurotransmitter acetylcholine (ACh).
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V77400 | (+)-Cevimeline hydrochloride hemihydrate ((+)-SNI-2011; (+)-AF102B hydrochloride hemihydrate) | (+)-Cevimeline HCl hemihydrate ((+)-SNI-2011) is a mAChR agonist. | |
|
V77403 | (-)-Cevimeline hydrochloride hemihydrate ((-)-SNI-2011; (-)-AF102B hydrochloride hemihydrate) | (-)-Cevimeline HCl hemihydrate ((-)-SNI-2011) is a mAChR agonist. | |
|
V85954 | (-)-Vesamicol (AH5183) | 112709-59-8 | |
|
V70547 | (1R,3S-)Solifenacin-d5 hydrochloride | 1217810-85-9 | (1R,3S-)Solifenacin-d5 ( HCl) is the deuterated form of Solifenacin D5 HCl. |
|
V70518 | (R)-Oxybutynin hydrochloride (Aroxybutynin hydrochloride) | 1207344-05-5 | (R)-Oxybutynin HCl is the racemic isomer of Oxybutynin HCl and is an orally bioactive muscarinic receptor antagonist. |
|
V107378 | (Rac)-5-Carboxy tolterodine | 1076199-77-3 | (Rac)-5-Carboxytolterodine is an inactive metabolite of the muscarinic acetylcholine receptor antagonist tolterodine. |
|
V70507 | (Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine; (Rac)-PNU-200577) | 200801-70-3 | (Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine) is an bioactive metabolite of Tolterodine and an mAChR antagonist (Kis for M1, M2, M3, M4, and M5 receptors are 2.3 nM, 2 nM, 2.5 nM, 2.8 nM and 2.9 nM). |
|
V70546 | (Rac)-5-Hydroxymethyl Tolterodine hydrochloride ((Rac)-Desfesoterodine hydrochloride; (Rac)-PNU-200577 hydrochloride) | 250214-40-5 | (Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine) HCl is an bioactive metabolite of Tolterodine and an mAChR antagonist (Kis for M1, M2, M3, M4 and M5 receptors are 2.3 nM each) , 2 nM, 2.5 nM, 2.8 nM and 2.9 nM). |
|
V70549 | (Rac)-5-Hydroxymethyl Tolterodine-d14 ((Rac)-Desfesoterodine-d14; (Rac)-PNU-200577-d14) | 1185071-13-9 | (Rac)-5-Hydroxymethyl Tolterodine-d14 is the deuterated form of (Rac)-5-Hydroxymethyl Tolterodine. |
|
V107033 | (S)-Tolterodine | 124937-53-7 | (S)-Tolterodine is a muscarinic acetylcholine receptor (mAChR) inhibitor with IC50 of 588 nM. |
|
V107616 | (±)-Darifenacin N-Oxide | 2416229-88-2 | (±)-Darifenacin N-oxide is an impurity of darifenacin. |
|
V105587 | 5-Hydroxymethyl tolterodine formate | 380636-49-7 | 5-Hydroxymethyltolterodine (formate) (PNU-200577 (formate)) is the active metabolite of the muscarinic acetylcholine receptor antagonists tolterodine and fesoterodine. |
![[D-Trp7,9,10]-Substance P TFA](http://www.invivochem.com/upload/1124/V77479.png)
|
V77479 | [D-Trp7,9,10]-Substance P TFA | [D-Trp7,9,10]-Substance P TFA is an analogue of substance P. | |
|
V101196 | AC-42 hydrochloride | 447407-36-5 | AC-42 HCl is the hydrochloride salt form of AC-42. |
|
V105497 | Aceclidine hydrochloride | 6109-70-2 | Acetoclidin-3-yl acetate hydrochloride is a modulator of M3 muscarinic acetylcholine receptors and an agonist of M1 receptors (EC50: 40 μM). |
|
V102851 | Acetylethylcholine mustard hydrochloride | 103994-00-9 | Acetylcholine mustard hydrochloride is a choline acetyltransferase inhibitor that reduces the contraction frequency of myotubes by inhibiting the synthesis of acetylcholine (Ach) with a half-maximal inhibitory concentration (IC50) of 1.22 mM. |
|
V103083 | AE9C90CB | 893426-98-7 | AE9C90CB is a muscarinic receptor antagonist with higher affinity for the M3 muscarinic receptor, with a pKi of 9.90, and is 20-fold more selective for the M3 muscarinic receptor than the M2 muscarinic receptor. |
|
V83603 | Antidepressant agent 6 | ||
|
V70498 | Arecaidine but-2-ynyl ester tosylate (ABET) | 119630-77-2 | Arecaidine but-2-ynyl ester tosylate (ABET) is a selective mAChR M2 agonist that dose-dependently reduces mean arterial pressure and heart rate in rats. |
|
V84784 | Arecaidine-propargyl ester tosylate | 147202-94-6 |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
