The acetylcholine receptors known as mAChRs (muscarinic acetylcholine receptors) are found in the cell membranes of some neurons and other cells. The primary end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system is one of their many functions. Because they are more sensitive to muscarine than to nicotine, mAChRs are so named. Nicotinic acetylcholine receptors (nAChRs), receptor ion channels that are also significant in the autonomic nervous system, are their counterparts. Numerous medications and other substances, such as scopolamine and pilocarpine, act as selective agonists or antagonists on these two different receptors. The brain and the autonomic ganglia are both rich sources of the neurotransmitter acetylcholine (ACh).
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V77400 | (+)-Cevimeline hydrochloride hemihydrate ((+)-SNI-2011; (+)-AF102B hydrochloride hemihydrate) | (+)-Cevimeline HCl hemihydrate ((+)-SNI-2011) is a mAChR agonist. | |
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V77403 | (-)-Cevimeline hydrochloride hemihydrate ((-)-SNI-2011; (-)-AF102B hydrochloride hemihydrate) | (-)-Cevimeline HCl hemihydrate ((-)-SNI-2011) is a mAChR agonist. | |
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V85954 | (-)-Vesamicol (AH5183) | 112709-59-8 | |
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V70547 | (1R,3S-)Solifenacin-d5 hydrochloride | 1217810-85-9 | (1R,3S-)Solifenacin-d5 ( HCl) is the deuterated form of Solifenacin D5 HCl. |
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V70518 | (R)-Oxybutynin hydrochloride (Aroxybutynin hydrochloride) | 1207344-05-5 | (R)-Oxybutynin HCl is the racemic isomer of Oxybutynin HCl and is an orally bioactive muscarinic receptor antagonist. |
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V70507 | (Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine; (Rac)-PNU-200577) | 200801-70-3 | (Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine) is an bioactive metabolite of Tolterodine and an mAChR antagonist (Kis for M1, M2, M3, M4, and M5 receptors are 2.3 nM, 2 nM, 2.5 nM, 2.8 nM and 2.9 nM). |
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V70546 | (Rac)-5-Hydroxymethyl Tolterodine hydrochloride ((Rac)-Desfesoterodine hydrochloride; (Rac)-PNU-200577 hydrochloride) | 250214-40-5 | (Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine) HCl is an bioactive metabolite of Tolterodine and an mAChR antagonist (Kis for M1, M2, M3, M4 and M5 receptors are 2.3 nM each) , 2 nM, 2.5 nM, 2.8 nM and 2.9 nM). |
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V70549 | (Rac)-5-Hydroxymethyl Tolterodine-d14 ((Rac)-Desfesoterodine-d14; (Rac)-PNU-200577-d14) | 1185071-13-9 | (Rac)-5-Hydroxymethyl Tolterodine-d14 is the deuterated form of (Rac)-5-Hydroxymethyl Tolterodine. |
![[D-Trp7,9,10]-Substance P TFA](http://www.invivochem.com/upload/1124/V77479.png)
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V77479 | [D-Trp7,9,10]-Substance P TFA | [D-Trp7,9,10]-Substance P TFA is an analogue of substance P. | |
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V10759 | Anisodamine | 55869-99-3 | Anisodamine is a ntural product extracted from Chinese solanacea plant, acting as a weak inhibitor/antagonist of alpha-1 adrenergic receptors and mAChRs. |
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V83603 | Antidepressant agent 6 | ||
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V70498 | Arecaidine but-2-ynyl ester tosylate (ABET) | 119630-77-2 | Arecaidine but-2-ynyl ester tosylate (ABET) is a selective mAChR M2 agonist that dose-dependently reduces mean arterial pressure and heart rate in rats. |
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V84784 | Arecaidine-propargyl ester tosylate | 147202-94-6 | |
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V83201 | AZD-2115 | AZD-2115 is a muscarinic antagonist/beta 2 agonist (MABA). | |
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V84978 | Baogongteng A ((-)-Bao Gong Teng A) | 74239-84-2 | |
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V12451 | Benzetimide HCl | 5633-14-7 | Benzetimide HCl, formerly known as EINECS 227-072-8, Spasmentral, and Dioxatrine, is a muscarinic acetylcholine receptor antagonist. |
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V70373 | Benztropine-d3 mesylate (benzatropine mesylate-d3; benztropine mesylate-d3) | 202529-16-6 | Benztropine-d3 (mesylate) is the deuterated form of Benztropine (mesylate). |
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V29679 | Bethanechol | 674-38-4 | Bethanechol (Carbamyl-β-methylcholine chloride), a parasympathomimetic choline carbamate and an analog of acetylcholine, is a selective muscarinic receptor agonist without any effect on nicotinic receptors. |
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V78408 | Bethanechol-d6 chloride (Carbamyl-β-methylcholine-d6 (chloride)) | Bethanechol-d6 (chloride) is the deuterated form of Bethanechol chloride. | |
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V12468 | Biperiden Hydrochloride | 1235-82-1 | Biperiden HCl (trade name Akineton; Akinophyl), the hydrochloride salt of Biperiden, is a potent muscarinic antagonist and a medication used to treat Parkinson disease and certain drug-induced movement disorders. |
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