Monoamine Oxidase

Monoamine Oxidase

A family of enzymes known as monoamine oxidases (MAO) catalyzes the oxidation of monoamines. In the majority of the body's cell types, they are discovered bound to the mitochondria's outer membrane. They are a member of the flavin-containing amine oxidoreductase protein family. The oxidative deamination of monoamines is catalyzed by monoamine oxidases. By using oxygen to remove an amine group from a molecule, the resulting aldehyde and ammonia are produced.Flavoproteins are monoamine oxidases because they have the cofactor FAD covalently bound to them. MAO dysfunction is thought to be the cause of a number of psychiatric and neurological disorders due to the critical part MAOs play in the inactivation of neurotransmitters. While MAO-B inhibitors are used alone or in combination to treat Alzheimer's and Parkinson's diseases, MAO-A inhibitors have antidepressant and antianxiety properties.

Monoamine Oxidase related products

Structure Cat No. Product Name CAS No. Product Description
V70662 (+)-Cinchonaminone 60305-15-9 (+)-Cinchonaminone displays MAO (monoamine oxidase) inhibitory activity.
V70685 (±)-Amiflamine (FLA 336) 77502-96-6 (±)-Amiflamine (FLA 336) is a potent MAO (monoamine oxidase) (MAO-A) with pIC50 of 5.57.
V70672 1,4-Naphthoquinone-d6 26473-08-5 1,4-Naphthoquinone-d6 is the deuterated form of 1,4-Naphthoquinone.
V70693 1-Methyl-2-undecyl-4(1H)-quinolone 59443-02-6 1-Methyl-2-undecyl-4(1H)-quinolone is a potent irreversible and selective monoamine oxidase type B (MAO-B) inhibitor.
V70643 4-Hydroxyderricin 55912-03-3 4-Hydroxyderricin is one of the main active ingredients of Ashitaba and is a potent and specific MAO-B (monoamine oxidase inhibitor) inhibitor (antagonist) with IC50 of 3.43 μM.
V70678 6-Acetonyl-N-methyldihydrodecarine 1253740-09-8 6-Acetonyl-N-methyldihydrodecarine is an alkaloid extracted from the roots of Zanthoxylum rigidum and is an inhibitor (blocker/antagonist) of MAO (monoamine oxidase).
V70640 Aminoacetone hydrochloride 7737-17-9 Aminoacetone HCl is the simplest single peptide.
V78050 Antioxidant agent-13 Antioxidant agent-13 (Compound 5f) is an antioxidant.
V5896 Bifemelane HCl 62232-46-6 Bifemelane HCl (MCI-2016) is a potent, selective and competitive inhibitor of MAO (monoamine oxidase) A (MAO-A) with Ki of 4.20 μM.
V85269 ChEs/MAOs-IN-1
V70684 Chrysophanol-1-O-β-gentiobioside (Chrysophanol-1-O-β-gentiobioside) 54944-38-6 Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside extracted from Cassia seeds.
V18542 Clorgyline HCl (M&B 9302, MB9302) 17780-75-5 Clorgyline, formerly known as Clorgiline, M&B 9302 or MB9302, is a potent,irreversible and selective inhibitor of monoamine oxidase (MAO), it is structurally related to pargyline which is described as an antidepressant.
V70668 Decaffeoylacteoside (Decaffeoylverbascoside; Verbasoside) 61548-34-3 Decaffeoylacteoside is an inhibitor (blocker/antagonist) of AChE/BChE/LOX with moderate activity.
V70669 Echitovenidine 7222-35-7 Echitovenidine is an alkaloid extracted from Alstonia yunnanensis.
V70670 ETAP 2575731-47-2 ETAP is an MAO-A and MAO-B inhibitor.
V70677 Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate 28705-46-6 Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate is a potent hMAO-B selective inhibitor (antagonist) with IC50 of 45.52 μM.
V67662 Glicoricone 161099-37-2 Glicoricone is a phenolic compound extracted from licorice.
V76938 Harmane-d (Harmane-d1) Harmane-d is the deuterium labelled form of Harmane.
V79700 Harmane-d2 (Harmane-d2) Harmane-d2 is the deuterium labelled form of Harmane.
V85743 hMAO-A-IN-1 1039315-88-2
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