Acute respiratory infections are frequently brought on by RSV (Respiratory syncytial virus). RSV has the ability to take advantage of host immunity and trigger a significant inflammatory response that damages the lungs and spreads the virus. A and B are the two main antigenic subgroups of the one RSV serotype.
RSV is a non-segmented, negative-sense, single-stranded enveloped RNA virus that is a member of the Pneumovirinae subfamily of the Paramyxoviridae family and the Pneumovirus genus. Since two overlapping open reading frames in the M2 mRNA result in two different matrix proteins, M2-1 and M2-2, its 10 genes encode 11 proteins. The G glycoprotein, the F glycoprotein, and the SH protein are the three proteins that make up the viral envelope. The RSV virus has two non-structural proteins (NS1 and NS2) in addition to the large (L) protein, nucleocapsid (N), phosphoprotein (P), matrix (M), and M2-1.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V54283 | (S)-Enzaplatovir ((S)-BTA-C585) | 1323077-88-8 | (S)-Enzaplatovir ((S)-BTA-C585) is the S-enantiomer of Enzaplatovir. |
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V54289 | 3,4-Di-O-caffeoyl quinic acid methyl ester (Macroantoin F) | 114637-83-1 | 3,4-Di-O-caffeoyl quinic acid methyl ester (Macroantoin F) is a dicaffeoyl analogue extracted from the rhizome of Elephantopus scaber Linn. |
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V54304 | 4,5-O-Dicaffeoyl quinic acid methyl ester | 188742-80-5 | 4,5-O-Dicaffeoyl quinic acid methyl ester (compound 4) is a dicaffeoylquinic acid with potent antiviral effect against respiratory syncytial virus (RSV) with IC50 of 0.63 μg/mL and a CC50 of 118.68 μg/mL. |
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V25182 | Ac-CoA Synthase Inhibitor1 | 508186-14-9 | Ac-CoA Synthase Inhibitor1, also known as ACSS2 Inhibitor or Ac-CoA Synthase Inhibitor I, is a Ac-CoA Synthase Inhibitor with antiviral effects. |
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V54305 | ACSS2-IN-1 | 2711039-08-4 | ACSS2-IN-1 (Cpmpound 1) is a potent inhibitor of ACSS2. |
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V54307 | Antiviral agent 10 | 312615-62-6 | antiviral compound 10 is an antiviral compound that can inhibit respiratory syncytial virus (RSV). |
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V52334 | BMS-433771 dihydrochloride hydrate | 543700-67-0 | BMS-433771 di-HCl hydrate is a potent orally bioactive respiratory syncytial virus (RSV) inhibitor. |
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V54308 | Clesrovimab (MK1654) | 2429913-18-6 | Clesrovimab (MK1654) is a fully human anti-RSV fusion (RSV F) glycoprotein monoclonal antibody (mAb). |
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V76072 | ent-11β-Hydroxyatis-16-ene-3,14-dione | 1092103-22-4 | ent-11β-Hydroxyatis-16-ene-3,14-dione (compound 11) is a diterpenoid developed from the fresh roots of Euphorbia jolkinii. |
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V52095 | Felvizumab (SB 209763; RSHZ19) | 167747-20-8 | Felvizumab (SB 209763) is a humanized IgG1κ monoclonal antibody (mAb) that targets a distinct neutralizing epitope on the RSV F glycoprotein. |
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V54309 | Genkwanol C | 151283-11-3 | Genkwanol C is a biflavonoid compound with potent in vitro anti-viral effect against respiratory syncytial virus (RSV). |
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V52048 | Gontivimab (ALX-0171; VR-465) | 1257358-38-5 | Gontivimab (ALX-0171; VR-465) is a potent anti-RSV pre-fusion F protein nanobody with a KD of 0.113 nM. |
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V54310 | hRSV-IN-1 | 749868-66-4 | hRSV-IN-1 is an inhibitor (blocker/antagonist) of respiratory syncytial virus (hRSV). |
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V80455 | JNJ-8003 | JNJ-8003 is a potent inhibitor of RSV Polymerase. | |
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V41176 | Motavizumab (MEDI-524) | 677010-34-3 | Motavizumab (MEDI-524) is an anti-human RSV (respiratory syncytial virus) monoclonal antibody (mAb). |
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V54311 | Nirsevimab (MEDI8897) | 1989556-22-0 | Nirsevimab (MEDI8897; Beyfortus) is a recombinant human respiratory syncytial virus (RSV) monoclonal antibody (mAb) with a modified Fc region that extends its half-life. |
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V35028 | Quercetin pentaacetate (Pentaacetylquercetin) | 1064-06-8 | Quercetin pentaacetate can interact with F protein, has low binding energy, good stability, and can block virus adhesion. |
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V4497 | Rilematovir (JNJ-678) | 1383450-81-4 | Rilematovir (JNJ678; JNJ-53718678; JNJ-678; JNJ53718678) is a novel, oral and potent fusion proteininhibitor with antiviral activity. |
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V54312 | RSV L-protein-IN-2 | 774130-99-3 | RSV L-protein-IN-2 (Compound A) is a noncompetitive RSV polymerase inhibitor (IC50= 4.5 μM). |
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V38122 | RSV L-protein-IN-3 | 868860-35-9 | RSV L-protein-IN-3 is a wild-type RSV polymerase inhibitor (antagonist) with IC50 of 10.4 μM and EC50 of 2.1 μM (RSV). |
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