Animal organ size is regulated by the Hippo signaling pathway, also referred to as the Salvador/Warts/Hippo (SWH) pathway, through the control of cell proliferation and apoptosis. The protein kinase Warts (Wts) is phosphorylated by Hpo in the Hippo pathway's core kinase cascade. Hpo is a protein kinase belonging to the Ste-20 family (also known as MST1/2 in mammals). Cell proliferation, apoptosis, and different stress reactions are among the cellular processes that this highly conserved group of serine/threonine kinases controls.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V117540 | Biotin-MST2 Recombinant Human Active Protein Kinase | MST2 is a serine/threonine protein kinase that plays a central role in the Hippo signaling pathway, which regulates cell proliferation, differentiation, and apoptosis during development. | |
|
V41374 | I3MT-3 | 459420-09-8 | I3MT-3 (also known as HMPSNE; EMT inhibitor-1;EMT inhibitor 1) is a novel, selective, potent, and membrane permeable inhibitor of 3MST (3-Mercaptopyruvate sulfurtransferase) with IC50 of 2.7 μM. |
|
V85329 | JA310 | 3022928-90-8 | |
|
V115299 | MR24 TFA | MR24 TFA is a derivative of G-5555 and is a mammalian STE20-like (MST) kinase inhibitor. | |
|
V112386 | MST3-IN-1 TFA | MST3-IN-1 TFA (compound LD-1) is a selective, orally effective MST3 inhibitor with an IC50 value of 122.4 nM. | |
|
V2017 | XMU-MP-1 | 2061980-01-4 | XMU-MP-1 is a potent,reversible and selective inhibitor of MST1/2 with IC50 values of 71.1 nM and 38.1 nM against MST1 and MST2, respectively. |
|
V98119 | α-Ionone | 127-41-3 | α-Ionone is an activator of the olfactory receptor OR10A6. |
|
V97039 | α-Ionone (Standard) | 127-41-3 | α-Ionone (Standard) is the analytical standard for α-ionone. |
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