The genetic material (DNA or RNA) of viral pathogens contains enzymes called viral proteases. Viral proteases catalyze the cleavage of particular peptide bonds in cellular proteins or viral polyprotein precursors. Viral proteases may attack the scissile peptide bond using various catalytic mechanisms involving either serine, cysteine, or aspartic acid residues. A high degree of specific recognition and cleavage is guaranteed by the enzyme's complementary substrate binding site's selective recognition of these sequence patterns.
The respiratory illness coronavirus disease 2019 (COVID-19) is caused by the SARS-CoV-2 coronavirus (SARS-CoV-2). SARS-CoV-2 entry requires transmembrane protease, serine 2 (TMPRSS2) to prime the initial spike protein. The cell's protease TMPRSS2 breaks open the virus's spike protein after a SARS-CoV-2 virion attaches to a target cell, revealing a fusion peptide.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V52846 | (+)-JNJ-A07 | 2135640-93-4 | (+)-JNJ-A07 is a potent pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. |
|
V52506 | (E)-3,4-Dimethoxycinnamic acid ((E)-3,4-Dimethoxycinnamic acid; (E)-O-Methylferulic acid) | 14737-89-4 | (E)-3,4-Dimethoxycinnamic acid is a less active isomer of 3,4-Dimethoxycinnamic acid. |
|
V54448 | 2'-Deoxy-2'-fluoro-l-uridine | 622785-69-7 | 2'-Deoxy-2'-fluoro-l-uridine is an L-nucleoside compound. |
|
V52961 | 2-Hydroxy-4-methylbenzenesulphonic acid ammonium | 79093-71-3 | 2-Hydroxy-4-methylbenzenesulphonic acid ammonium is an impurity in Policyresulen. |
|
V54444 | 4-Hydroxy-2-methylbenzenesulfonic acid ammonium | 2742982-16-5 | 4-Hydroxy-2-methylbenzenesulfonic acid ammonium is an impurity in Policyresulen. |
|
V52748 | 4-Methylanisole-d3 (4-Methoxytoluene-d3) | 14202-49-4 | 4-Methylanisole-d3 is the deuterium labelled form of 4-Methylanisole. |
|
V52751 | 4-Phenylbutyric acid-d11 (4-PBA-d11; Benzenebutyric acid-d11) | 358730-86-6 | 4-Phenylbutyric acid-d11 is the deuterated form of 4-Phenylbutyric acid. |
|
V52750 | 4-Phenylbutyric acid-d2 (4-PBA-d2; Benzenebutyric acid-d2) | 461391-24-2 | 4-Phenylbutyric acid-d2 is the deuterated form of 4-Phenylbutyric acid. |
|
V52749 | 4-Phenylbutyric acid-d5 (4-PBA-d5; Benzenebutyric acid-d5) | 64138-52-9 | 4-Phenylbutyric acid-d5 is the deuterated form of 4-Phenylbutyric acid. |
|
V54443 | 5-Bromo-2′-deoxy-2′-fluorouridine | 55612-18-5 | 5-Bromo-2′-deoxy-2′-fluorouridine (Example 1) is a 5-halogen analog with potential use as an antiviral compound. |
|
V77588 | 5-Hydroxytoluene-2,4-disulphonic acid diammonium | 5-Hydroxytoluene-2,4-disulphonic acid diammonium is an impurity in Policyresulen. | |
|
V52464 | A2ti-1 | 570390-00-0 | A2ti-1 is a selective, high-affinity inhibitor of the annexin A2/S100A10 heterotetramer (A2t) with IC50 of 24 μM. |
|
V52463 | A2ti-2 | 482646-13-9 | A2ti-2 is a selective, low-affinity inhibitor of the annexin A2/S100A10 heterotetramer (A2t) with IC50 of 230 μM. |
|
V54445 | AG-7404 | 343565-99-1 | AG-7404 is a picornavirus 3C protease inhibitor (antagonist) with anti-poliovirus activity (EC50=0.080-0.674 μM). |
|
V52640 | Anthraquinone-d8 (Anthraquinone-d8) | 10439-39-1 | Anthraquinone-d8 is the deuterium labelled form of Anthraquinone. |
|
V78110 | Anticancer agent 90 | Anticancer agent 90 is a benzothiazole-2-thiophene S-glycoside analogue with anticancer effect. | |
|
V52829 | Aspirin-d3 (Acetylsalicylic Acid-d3; ASA-d3) | 921943-73-9 | Aspirin-d3 is the deuterium labelled form of Aspirin. |
|
V52794 | Aspirin-d4 (Acetylsalicylic Acid-d4; ASA-d4) | 97781-16-3 | Aspirin-d4 is the deuterium labelled form of Aspirin. |
|
V52186 | DENV-IN-8 | 1809464-07-0 | DENV-IN-8 (Compound 5e) is a DENV2 inhibitor (antagonist) with EC50 of 0.068 μM. |
|
V52185 | DENV-IN-9 | 791838-63-6 | DENV-IN-9 (Compound 5f) is a DENV2 inhibitor (antagonist) with EC50 of 0.88 μM. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
