| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V84636 | 4,4'-Di-O-methylellagic acid (4,4'-DiOMEA; Nasutin C) | 3374-77-4 | |
|
V80838 | 8BTC | 8BTC (compound 4w) is a potent covalent Notum inhibitor (antagonist) with IC50 of 2.5 nM. | |
|
V69164 | ABC99 | 2331255-53-7 | BC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM (IC50=13 nM). |
|
V69166 | Box5 | 1206604-29-6 | Box5 is a potent Wnt5a antagonist. |
|
V77189 | Box5 TFA | Box5 TFA is a potent Wnt5a antagonist. | |
|
V69165 | Carboxylesterase-IN-3 | 2764748-92-5 | Carboxylesterase-IN-3 (compound 4y) is a potent Carboxylesterase Notum inhibitor (antagonist) with IC50 less than or equal to 10 nM. |
|
V69169 | Cardionogen 1 (CDNG1/vuc230) | 577696-37-8 | Cardionogen 1 (CDNG1/vuc230) is a Wnt signaling pathway inhibitor that can slow down Myc-induced liver tumorigenesis. |
|
V77001 | Foxy-5 TFA | Foxy-5 TFA is a WNT5A agonist, a mimetic peptide of WNT5A, and a non-classical member of the Wnt family. | |
|
V86268 | Fz7-21S | 2247635-24-9 | |
|
V85009 | FZD7 antagonist 1 | 2416664-25-8 | |
|
V69163 | Ipafricept (OMP-54F28; FZD8-Fc) | 1391727-24-4 | Ipafricept (OMP-54F28; FZD8-Fc) is a first-in-class recombinant fusion protein consisting of the extracellular portion of the human Frizzled-8 receptor fused to a human IgG1 Fc fragment that binds Wnt ligands. |
|
V69168 | IWP-2-V2 | 877618-79-6 | IWP-2-V2 is an IWP-2 analog that retains activity on the Wnt/β-catenin pathway. |
|
V76844 | KY-02327 acetate | KY-02327 acetate is a metabolically stable analog of KY-02061 and a potent inhibitor of the Dishevelled (Dvl)-CXXC5 interaction. | |
|
V67511 | NLS-StAx-h | 2872559-21-0 | NLS-StAx-h is a selective, cell-permeable (penetrable), immobilized peptide inhibitor of Wnt signaling with IC50 of 1.4 μM. |
|
V85682 | Pen-N3 | ||
|
V69167 | Pin1 modulator 1 | 301688-74-4 | Pin1 modulator 1 (compound IIb-219) is a modulator that specifically targets β-Catenin and inhibits the Wnt pathway. |
|
V69173 | Porcn-IN-2 | 1900754-65-5 | Porcn-IN-2 (Example 107) is a Wnt inhibitor (antagonist) with IC50 of 0.05 nM. |
|
V67518 | Sempervirine nitrate | 17994-15-9 | Sempervirine is an alkaloid derived from Gelsemium elegans Benth. |
|
V69171 | Tabituximab barzuxetan (exclude Y90) (OTSA101-DTPA; OTSA101-DTPA-90Y; OTSA101-SS01) | 1612758-88-9 | Tabituximab barzuxetan (exclude Y90) is a radioimmunoconjugate consisting of a humanized monoclonal antibody (mAb) targeting FZD-10 (OTSA-101). |
|
V69170 | Vantictumab (OMP-18R5) | 1345009-45-1 | Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody (mAb). |
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