| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V104745 | 21H7 | 217317-45-8 | 21H7 is a selective inhibitor of the Wnt/b-catenin pathway. |
|
V102465 | 3289-8625 | 294891-81-9 | 3289-8625 is an inhibitor of the PDZ domain of Dishevelled (Dvl) protein (Kd=10.6 μM), which inhibits Wnt signaling. |
|
V84636 | 4,4'-Di-O-methylellagic acid (4,4'-DiOMEA; Nasutin C) | 3374-77-4 | |
|
V80838 | 8BTC | 8BTC (compound 4w) is a potent covalent Notum inhibitor (antagonist) with IC50 of 2.5 nM. | |
|
V69164 | ABC99 | 2331255-53-7 | BC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM (IC50=13 nM). |
|
V128677 | AMG-167 | 1798349-30-0 | AMG-167 is an anticancer monoclonal antibody that targets bone protein. |
|
V129151 | Antiproliferative agent-76 | 33757-62-9 | Antiproliferative agent-76 is an 8-sulfonamide quinoline derivative and a selective anticancer agent. |
|
V129223 | APD-94 | 877810-03-2 | APD-94 is a dual inhibitor that targets both tubulin and Bmi-1. |
|
V129727 | AZD8701 sodium scrambled negative control | The AZD8701 sodium scrambled negative control is a negative control with the sequence of AZD8701 sodium salt scrambled. | |
|
V129941 | BCN512 | 346691-54-1 | BCN512 is an SFRP1 inhibitor that can inhibit tissue fibrosis. |
|
V130390 | BMD4503-1 | 301357-76-6 | BMD4503-1 is a quinoxaline derivative. |
|
V69166 | Box5 | 1206604-29-6 | Box5 is a potent Wnt5a antagonist. |
|
V77189 | Box5 TFA | Box5 TFA is a potent Wnt5a antagonist. | |
|
V88134 | C1s Enzyme | C1s Enzyme is a subunit of the complement C1 complex and can activate complement as a serine protease. | |
|
V69165 | Carboxylesterase-IN-3 | 2764748-92-5 | Carboxylesterase-IN-3 (compound 4y) is a potent Carboxylesterase Notum inhibitor (antagonist) with IC50 less than or equal to 10 nM. |
|
V69169 | Cardionogen 1 (CDNG1/vuc230) | 577696-37-8 | Cardionogen 1 (CDNG1/vuc230) is a Wnt signaling pathway inhibitor that can slow down Myc-induced liver tumorigenesis. |
|
V131068 | Cardionogen-2 | 578755-52-9 | Cardionogen-2 is a biphasic regulator of cardiac development; depending on the stage of treatment, it can either promote or inhibit cardiac formation. |
|
V98449 | CCT070535 | 485319-41-3 | CCT070535 blocks TCF-dependent transcription at the TCF level, with GI50 values of 17.6 μM, 11.1 μM, 11.8 μM, and 13.4 μM in HT29 (APC mutation), HCT116 (oncogenic β-catenin), SW480 (APC mutation), and SNU475 (Axin mutation) cells, respectively. |
|
V131499 | Chikusetsusaponin IVa methyl ester | 58546-61-5 | Chikusetsusaponin IVa methyl ester is a natural triterpenoid saponin compound. |
|
V131696 | Cibotercept | 2769700-97-0 | Cibotercept is a novel, modified, investigational activin receptor type IIB (ActRIIB) ligand trap designed to target specific TGF-β ligands, including activins A and B, GDF 8 and 11, to rebalance the activin receptor type II signaling defects observed in PAH. |