Wnt

Wnt

Wnt related products

Structure Cat No. Product Name CAS No. Product Description
V84636 4,4'-Di-O-methylellagic acid (4,4'-DiOMEA; Nasutin C) 3374-77-4
V80838 8BTC 8BTC (compound 4w) is a potent covalent Notum inhibitor (antagonist) with IC50 of 2.5 nM.
V69164 ABC99 2331255-53-7 BC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM (IC50=13 nM).
V69166 Box5 1206604-29-6 Box5 is a potent Wnt5a antagonist.
V77189 Box5 TFA Box5 TFA is a potent Wnt5a antagonist.
V69165 Carboxylesterase-IN-3 2764748-92-5 Carboxylesterase-IN-3 (compound 4y) is a potent Carboxylesterase Notum inhibitor (antagonist) with IC50 less than or equal to 10 nM.
V69169 Cardionogen 1 (CDNG1/vuc230) 577696-37-8 Cardionogen 1 (CDNG1/vuc230) is a Wnt signaling pathway inhibitor that can slow down Myc-induced liver tumorigenesis.
V77001 Foxy-5 TFA Foxy-5 TFA is a WNT5A agonist, a mimetic peptide of WNT5A, and a non-classical member of the Wnt family.
V86268 Fz7-21S 2247635-24-9
V85009 FZD7 antagonist 1 2416664-25-8
V69163 Ipafricept (OMP-54F28; FZD8-Fc) 1391727-24-4 Ipafricept (OMP-54F28; FZD8-Fc) is a first-in-class recombinant fusion protein consisting of the extracellular portion of the human Frizzled-8 receptor fused to a human IgG1 Fc fragment that binds Wnt ligands.
V69168 IWP-2-V2 877618-79-6 IWP-2-V2 is an IWP-2 analog that retains activity on the Wnt/β-catenin pathway.
V76844 KY-02327 acetate KY-02327 acetate is a metabolically stable analog of KY-02061 and a potent inhibitor of the Dishevelled (Dvl)-CXXC5 interaction.
V67511 NLS-StAx-h 2872559-21-0 NLS-StAx-h is a selective, cell-permeable (penetrable), immobilized peptide inhibitor of Wnt signaling with IC50 of 1.4 μM.
V85682 Pen-N3
V69167 Pin1 modulator 1 301688-74-4 Pin1 modulator 1 (compound IIb-219) is a modulator that specifically targets β-Catenin and inhibits the Wnt pathway.
V69173 Porcn-IN-2 1900754-65-5 Porcn-IN-2 (Example 107) is a Wnt inhibitor (antagonist) with IC50 of 0.05 nM.
V67518 Sempervirine nitrate 17994-15-9 Sempervirine is an alkaloid derived from Gelsemium elegans Benth.
V69171 Tabituximab barzuxetan (exclude Y90) (OTSA101-DTPA; OTSA101-DTPA-90Y; OTSA101-SS01) 1612758-88-9 Tabituximab barzuxetan (exclude Y90) is a radioimmunoconjugate consisting of a humanized monoclonal antibody (mAb) targeting FZD-10 (OTSA-101).
V69170 Vantictumab (OMP-18R5) 1345009-45-1 Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody (mAb).
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