Thyroid Hormone Receptor

Thyroid Hormone Receptor

Thyroid hormone receptor is a member of the nuclear receptor superfamily that shuttles between the cytosol and nucleus.Thyroid hormone (T3)-mediated biological activities are mediated by thyroid hormone receptors, ligand-dependent transcription factors. Two genes, one for TR and the other for TR, encode the primary isoforms of thyroid hormone receptors, including TR1, TR2, TR1, and TR2. The pleiotropic effects of the thyroid hormone (T3) on growth, development, and differentiation as well as the preservation of metabolic equilibrium are mediated by the thyroid hormone receptors.

Thyroid hormone receptors are zinc finger transcription factors belonging to the erbA superfamily that bind to DNA at particular response element sequences called TREs and trigger gene expression in response to thyroid hormone (T3). It has been demonstrated that thyroid hormone receptors can form monomers, homodimers, or heterodimers with the retinoid X receptor (RXR), another member of the erbA superfamily, to bind DNA.

Thyroid Hormone Receptor related products

Structure Cat No. Product Name CAS No. Product Description
V67826 1α-Hydroxy-3-epi-vitamin D3 58028-00-5
V3920 ABALOPARATIDE 247062-33-5 Abaloparatide (Trade name Tymlos; formerly known as BA-058; ITM-058; BIM 44058) is a 34 amino acid synthetic analog of parathyroid hormone-related protein (PTHrP) that is used to treat osteoporosis.
V77309 Abaloparatide TFA (Abaloparatide; BA 058 TFA; BIM 44058 TFA)
V67812 Biotin-(L-Thyroxine) 149734-00-9
V67815 Debutyldronedarone hydrochloride (SR35021 hydrochloride) 197431-02-0
V67819 DPC-AJ1951 943519-33-3
V77069 DPC-AJ1951 TFA
V67817 DS08210767 2376334-75-5
V77064 DS69910557
V76969 Glutaurine TFA (Litoralon TFA)
V29928 L-Thyroxine sodium salt pentahydrate 6106-07-6 L-Thyroxine sodium salt pentahydrate is an endogenous iodine-bearing thyroid hormone produced from thyroglobulin in the thyroid follicular cells.
V67829 L-Thyroxine-13C6 (L-Thyroxine-13C6) 720710-30-5
V30180 Liothyronine sodium 55-06-1 Liothyronine sodium, the sodium of liothyronine, is a potent agonist of both thyroid hormone receptors TRα and TRβ.
V67824 Liothyronine-13C6-1 (Triiodothyronine-13C6; Triiodothyronine-13C6-1; 3,3',5-Triiodo-L-thyronine-13C6-1; T3-13C6-1) 1213431-76-5
V67818 Liothyronine-13C9,15N (Triiodothyronine-13C9,15N; 3,3',5-Triiodo-L-thyronine-13C9,15N; T3-13C9,15N) 1213569-04-0
V67814 NH-3 447415-26-1
V67828 Osteostatin (human) (Human PTHrP(107-139)) 137348-10-8
V76659 Parathyroid hormone (1-34) (rat) acetate
V81042 Parathyroid Hormone (1-34), bovine TFA
V76658 Parathyroid Hormone (1-34), human, biotinylated
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