| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V0084 | A-804598 (A804598) | 1125758-85-1 | A-804598(A 804598) is a structurally novel, CNS penetrant, potent, competitive, and selective antagonist of the purinergic P2X7 receptors (IC50 = 10 nM, 9 nM and 11 nM for rat, mouse and human P2X7 receptors respectively) with potential anti-inflammatory activity. |
|
V1305 | A-438079 HCl | 899431-18-6 | A-438079 HCl (A438079; A 438079),the hydrochloride salt of-438079,is a novel, potent, and selective P2X7 receptor antagonist with anti-Parkinsons disease effects. |
|
V5171 | AF-353 (Ro-4) | 865305-30-2 | AF-353 (Ro-4; AF353) is a novel, highly potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist with a pIC50of 8.0 for both human and rat P2X3, and with a pIC50of 7.3 for human P2X2/3. |
|
V17316 | BX430 | 688309-70-8 | BX430 is a novel, potent, selective allosteric/con-competitive antagonist of human P2X4 receptor channels with an IC50 of 0.54 μM. |
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V1302 | MRS 2578 | 711019-86-2 | MRS2578 (MRS-2578; MRS 2578) is a potent andselectiveP2Y6 receptor antagonist with potentially usefulness in controlling persistent storage symptoms in obstructed patients. |
|
V1300 | Prasugrel (PCR 4099; CS-747) | 150322-43-3 | Prasugrel (formerly CS-747,PCR-4099; LY-640315;trade name Effient; Prasita),a piperazine derivative,is an irreversible and thienopyridine-based ADP receptor (P2Y12) antagonist approvedas an antiplatelet and anticoagulantdrug used for the reduction of thrombotic cardiovascular events. |
|
V1303 | Ticagrelor (AZD6140) | 274693-27-5 | Ticagrelor (formerly AZD-6140; AR-C 126532XX; AZD6140;AR-C126532XX; Trade name: Brilinta; Brilique; Possia) is the first reversibly binding, potent and orally bioactiveP2Y12 receptor antagonist used as an antiplatelet and anticoagulant. |
|
V1304 | Ticlopidine HCl | 53885-35-1 | Ticlopidine HCl (Ticlodix; Ticlodone; 53-32C; 5332C; trade name Ticlid),the hydrochloride salt of ticlopidine, is a potentP2 receptor inhibitor against used as antiplatelet and anticoagulant. |
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V1301 | Clopidogrel sulfate | 120202-66-6 | Clopidogrel sulfate (Plavix; Zyllt; Osvix; Plavitor, SR-25990C), the sulfate salt ofClopidogrel, is an orally bioavailable, thienopyridine class of antiplatelet agent acting as an irreversible inhibitor of ADP receptor (P2Y12). |