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V0084
|
A-804598 (A804598)
|
1125758-85-1 |
A-804598(A 804598) is a structurally novel, CNS penetrant, potent, competitive, and selective antagonist of the purinergic P2X7 receptors (IC50 = 10 nM, 9 nM and 11 nM for rat, mouse and human P2X7 receptors respectively) with potential anti-inflammatory activity. |
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V1305
|
A-438079 HCl
|
899431-18-6 |
A-438079 HCl (A438079; A 438079),the hydrochloride salt of-438079,is a novel, potent, and selective P2X7 receptor antagonist with anti-Parkinsons disease effects. |
|
V5171
|
AF-353 (Ro-4)
|
865305-30-2 |
AF-353 (Ro-4; AF353) is a novel, highly potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist with a pIC50of 8.0 for both human and rat P2X3, and with a pIC50of 7.3 for human P2X2/3. |
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V17316
|
BX430
|
688309-70-8 |
BX430 is a novel, potent, selective allosteric/con-competitive antagonist of human P2X4 receptor channels with an IC50 of 0.54 μM. |
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V1302
|
MRS 2578
|
711019-86-2 |
MRS2578 (MRS-2578; MRS 2578) is a potent andselectiveP2Y6 receptor antagonist with potentially usefulness in controlling persistent storage symptoms in obstructed patients. |
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V1300
|
Prasugrel (PCR 4099; CS-747)
|
150322-43-3 |
Prasugrel (formerly CS-747,PCR-4099; LY-640315;trade name Effient; Prasita),a piperazine derivative,is an irreversible and thienopyridine-based ADP receptor (P2Y12) antagonist approvedas an antiplatelet and anticoagulantdrug used for the reduction of thrombotic cardiovascular events. |
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V1303
|
Ticagrelor (AZD6140)
|
274693-27-5 |
Ticagrelor (formerly AZD-6140; AR-C 126532XX; AZD6140;AR-C126532XX; Trade name: Brilinta; Brilique; Possia) is the first reversibly binding, potent and orally bioactiveP2Y12 receptor antagonist used as an antiplatelet and anticoagulant. |
|
V1304
|
Ticlopidine HCl
|
53885-35-1 |
Ticlopidine HCl (Ticlodix; Ticlodone; 53-32C; 5332C; trade name Ticlid),the hydrochloride salt of ticlopidine, is a potentP2 receptor inhibitor against used as antiplatelet and anticoagulant. |
|
V1301
|
Clopidogrel sulfate
|
120202-66-6 |
Clopidogrel sulfate (Plavix; Zyllt; Osvix; Plavitor, SR-25990C), the sulfate salt ofClopidogrel, is an orally bioavailable, thienopyridine class of antiplatelet agent acting as an irreversible inhibitor of ADP receptor (P2Y12). |