Tie

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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Tie

Tie related products

Cat No.	Product Name	CAS No.	Product Description
V108460	6-Hydroxy-2,2′,4,4′-tetrabromodiphenyl ether	79755-43-4	6-Hydroxy-2,2′,4,4′-Tetrabromodiphenyl ether is a selective Tie2 kinase inhibitor with an IC50 value of 2.1 μM.
V120024	AMG-780		AMG-780 is a fully human IgG2 antibody that targets angiopoietin 1 (Ang1) (IC50 = 4.5 nM) and angiopoietin 2 (Ang2) (IC50 = 0.06 nM).
V103645	BSF-466895	262442-90-0	BSF-466895 (A-422885.66) is a Tie2 inhibitor with IC50 of 5 nM and also inhibits Tie1.
V69579	TIE-2/VEGFR-2 kinase-IN-1	453590-24-4	TIE-2/VEGFR-2 kinase-IN-1 is used to synthesize TIE-2 or VEGFR-2 inhibitors, obtained from patent WO2003022852, Example 14.
V69577	TIE-2/VEGFR-2 kinase-IN-2	501693-48-7	TIE-2/VEGFR-2 kinase-IN-2 is a potent dual (bifunctional) inhibitor of VEGFR2 and Tie-2 with pIC50s of 8.61 and 8.56 respectively.
V69575	TIE-2/VEGFR-2 kinase-IN-3	433224-09-0	TIE-2/VEGFR-2 kinase-IN-3, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor blocker/inhibitor (antagonist) with IC50s of 6.9 nM and 3.5 nM respectively.
V69574	TIE-2/VEGFR-2 kinase-IN-4	433224-29-4	TIE-2/VEGFR-2 kinase-IN-4, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor blocker/inhibitor (antagonist) with IC50s of 5.2 nM and 5.1 nM respectively.
V69576	TIE-2/VEGFR-2 kinase-IN-5	1014407-83-0	TIE-2/VEGFR-2 kinase-IN-5 is an anti-angiogenic agent.
V69578	Tie2 kinase inhibitor 2	1020412-97-8	Tie2 kinase inhibitor 2 (compound 7) is a selective Tie2 kinase inhibitor (antagonist) with IC50 of 1 μM.
V118922	TIE2 R849W Recombinant Human Active Protein Kinase		TIE2 plays a crucial role in angiogenesis and maintenance.
V118924	TIE2 Y1108F Recombinant Human Active Protein Kinase		TIE2 plays a crucial role in angiogenesis and maintenance.
V119026	TIE2 Y897S Recombinant Human Active Protein Kinase		TIE2 plays a crucial role in angiogenesis and maintenance.
V89064	Vasculotide	1359657-45-6	Vasculotide, an angiopoietin-1 analog, is a Tie-2 activator that induces Tie-2 phosphorylation.
V106175	Vasculotide TFA		Vasculotide TFA is an angiopoietin-1 analog and a Tie-2 activator that induces Tie-2 phosphorylation.