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Tie

Tie

Tie related products

Structure Cat No. Product Name CAS No. Product Description
6-Hydroxy-2,2′,4,4′-tetrabromodiphenyl ether V108460 6-Hydroxy-2,2′,4,4′-tetrabromodiphenyl ether 79755-43-4 6-Hydroxy-2,2′,4,4′-Tetrabromodiphenyl ether is a selective Tie2 kinase inhibitor with an IC50 value of 2.1 μM.
AMG-780 V120024 AMG-780 AMG-780 is a fully human IgG2 antibody that targets angiopoietin 1 (Ang1) (IC50 = 4.5 nM) and angiopoietin 2 (Ang2) (IC50 = 0.06 nM).
ASKG-712 V129505 ASKG-712 ASKG-712 is a recombinant anti-VEGF humanized monoclonal antibody and Ang-2 antagonistic peptide fusion protein.
BSF-466895 V103645 BSF-466895 262442-90-0 BSF-466895 (A-422885.66) is a Tie2 inhibitor with IC50 of 5 nM and also inhibits Tie1.
DX-2240 V134776 DX-2240 DX-2240 is a human monoclonal antibody (mAb) that targets TIE1.
TIE-2/VEGFR-2 kinase-IN-1 V69579 TIE-2/VEGFR-2 kinase-IN-1 453590-24-4 TIE-2/VEGFR-2 kinase-IN-1 is used to synthesize TIE-2 or VEGFR-2 inhibitors, obtained from patent WO2003022852, Example 14.
TIE-2/VEGFR-2 kinase-IN-2 V69577 TIE-2/VEGFR-2 kinase-IN-2 501693-48-7 TIE-2/VEGFR-2 kinase-IN-2 is a potent dual (bifunctional) inhibitor of VEGFR2 and Tie-2 with pIC50s of 8.61 and 8.56 respectively.
TIE-2/VEGFR-2 kinase-IN-3 V69575 TIE-2/VEGFR-2 kinase-IN-3 433224-09-0 TIE-2/VEGFR-2 kinase-IN-3, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor blocker/inhibitor (antagonist) with IC50s of 6.9 nM and 3.5 nM respectively.
TIE-2/VEGFR-2 kinase-IN-4 V69574 TIE-2/VEGFR-2 kinase-IN-4 433224-29-4 TIE-2/VEGFR-2 kinase-IN-4, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor blocker/inhibitor (antagonist) with IC50s of 5.2 nM and 5.1 nM respectively.
TIE-2/VEGFR-2 kinase-IN-5 V69576 TIE-2/VEGFR-2 kinase-IN-5 1014407-83-0 TIE-2/VEGFR-2 kinase-IN-5 is an anti-angiogenic agent.
Tie2 kinase inhibitor 2 V69578 Tie2 kinase inhibitor 2 1020412-97-8 Tie2 kinase inhibitor 2 (compound 7) is a selective Tie2 kinase inhibitor (antagonist) with IC50 of 1 μM.
TIE2 R849W Recombinant Human Active Protein Kinase V118922 TIE2 R849W Recombinant Human Active Protein Kinase TIE2 plays a crucial role in angiogenesis and maintenance.
TIE2 Y1108F Recombinant Human Active Protein Kinase V118924 TIE2 Y1108F Recombinant Human Active Protein Kinase TIE2 plays a crucial role in angiogenesis and maintenance.
TIE2 Y897S Recombinant Human Active Protein Kinase V119026 TIE2 Y897S Recombinant Human Active Protein Kinase TIE2 plays a crucial role in angiogenesis and maintenance.
Trebananib V146408 Trebananib 894356-79-7 Trebananib is an Fc fusion peptide antibody.
UBX2050 V146716 UBX2050 UBX2050 is a human monoclonal antibody (mAb) that targets TIE2.
Vasculotide V89064 Vasculotide 1359657-45-6 Vasculotide, an angiopoietin-1 analog, is a Tie-2 activator that induces Tie-2 phosphorylation.
Vasculotide TFA V106175 Vasculotide TFA Vasculotide TFA is an angiopoietin-1 analog and a Tie-2 activator that induces Tie-2 phosphorylation.
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