| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V69579 | TIE-2/VEGFR-2 kinase-IN-1 | 453590-24-4 | TIE-2/VEGFR-2 kinase-IN-1 is used to synthesize TIE-2 or VEGFR-2 inhibitors, obtained from patent WO2003022852, Example 14. |
|
V69577 | TIE-2/VEGFR-2 kinase-IN-2 | 501693-48-7 | TIE-2/VEGFR-2 kinase-IN-2 is a potent dual (bifunctional) inhibitor of VEGFR2 and Tie-2 with pIC50s of 8.61 and 8.56 respectively. |
|
V69575 | TIE-2/VEGFR-2 kinase-IN-3 | 433224-09-0 | TIE-2/VEGFR-2 kinase-IN-3, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor blocker/inhibitor (antagonist) with IC50s of 6.9 nM and 3.5 nM respectively. |
|
V69574 | TIE-2/VEGFR-2 kinase-IN-4 | 433224-29-4 | TIE-2/VEGFR-2 kinase-IN-4, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor blocker/inhibitor (antagonist) with IC50s of 5.2 nM and 5.1 nM respectively. |
|
V69576 | TIE-2/VEGFR-2 kinase-IN-5 | 1014407-83-0 | TIE-2/VEGFR-2 kinase-IN-5 is an anti-angiogenic agent. |
|
V69578 | Tie2 kinase inhibitor 2 | 1020412-97-8 | Tie2 kinase inhibitor 2 (compound 7) is a selective Tie2 kinase inhibitor (antagonist) with IC50 of 1 μM. |
|
V89064 | Vasculotide | 1359657-45-6 | Vasculotide, an angiopoietin-1 analog, is a Tie-2 activator that induces Tie-2 phosphorylation. |
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