yingweiwo

Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
(+)-7-Isomethyljasmonate V108007 (+)-7-Isomethyljasmonate 95722-42-2 (+)-7-isomethyljasmonic acid ester (methyl(+)-7-isojasmonic acid ester) is a metabolite in the jasmonic acid synthesis pathway.
(1S)-1,4-Anhydro-1-C-(2,4-difluoro-5-methylphenyl)-D-ribitol V75686 (1S)-1,4-Anhydro-1-C-(2,4-difluoro-5-methylphenyl)-D-ribitol 875302-27-5 (1S)-1,4-Anhydro-1-C-(2,4-difluoro-5-methylphenyl)-D-ribitol is an analogue of purine nucleoside.
(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol V55558 (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol 263701-23-1 (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is an analogue of purine nucleoside.
(2’,3’,5’-Tri-O-acetyl)uridine 5-carboxylic acid V55999 (2',3',5'-Tri-O-acetyl)uridine 5-carboxylic acid 174653-39-5 (2',3',5'-Tri-O-acetyl)uridine 5-carboxylic acid is an analogue of purine nucleoside.
(2'OMe-5'p(S)-A)pG V110892 (2'OMe-5'p(S)-A)pG 2295879-58-0 (2'OMe-5'p(S)-A)pG is a monomeric raw material that can be used for nucleic acid synthesis.
(2'OMe-5'p-m6A)pG V111640 (2'OMe-5'p-m6A)pG 1207283-40-6 (2'OMe-5'p-m6A)pG is a monomeric raw material that can be used for nucleic acid synthesis.
(2'OMe-5'pA)pG V111467 (2'OMe-5'pA)pG 62828-60-8 (2'OMe-5'pA)pG is a monomeric raw material that can be used for nucleic acid synthesis.
(2'OMe-5'pA)pU V111510 (2'OMe-5'pA)pU 2956650-76-1 (2'OMe-5'pA)pU TEA salt is a monomeric raw material that can be used for nucleic acid synthesis.
(2'OMe-5'pG)pG V110947 (2'OMe-5'pG)pG 2638447-65-9 (2'OMe-5'pG)pG is a monomeric raw material that can be used for nucleic acid synthesis.
(2'OMe-5'pp-m6A)pG V111662 (2'OMe-5'pp-m6A)pG 2956650-87-4 (2'OMe-5'pp-m6A)pG is a monomeric raw material that can be used for nucleic acid synthesis.
(2'OMe-5'pU)pU V111699 (2'OMe-5'pU)pU 57197-82-7 (2'OMe-5'pU)pU is a monomeric raw material that can be used for nucleic acid synthesis.
(2-Amino-1-hydroxyethyl)phosphonate V110193 (2-Amino-1-hydroxyethyl)phosphonate 41744-58-5 (2-Amino-1-hydroxyethyl)phosphonate (1-hydroxy-2-aminoethylphosphonic acid) is a nucleoside metabolite.
(24E)-3α,7α-Dihydroxy-5β-cholest-24-enoyl-CoA V109577 (24E)-3α,7α-Dihydroxy-5β-cholest-24-enoyl-CoA 211363-24-5 (24E)-3α,7α-dihydroxy-5β-cholest-24-enoyl-CoA is a nucleoside metabolite.
(25R)-3Alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA V109733 (25R)-3Alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA 114987-52-9 (25R)-3α,7α-dihydroxy-5β-cholestanyl-CoA is a coenzyme A derivative.
(25R)-3α,7α,12α-Trihydroxy-5β-cholestan-26-oyl-CoA V110189 (25R)-3α,7α,12α-Trihydroxy-5β-cholestan-26-oyl-CoA 21400-58-8 (25R)-3α,7α,12α-trihydroxy-5β-cholestane-26-acyl-CoA is a nucleoside metabolite.
(25S)-3Alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA V110190 (25S)-3Alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA 211505-06-5 (25S)-3α,7α,12α-trihydroxy-5β-cholestane-26-acyl-CoA is a nucleoside metabolite.
(2R,3S)-3-Methylmalic acid V108657 (2R,3S)-3-Methylmalic acid 152204-30-3 (2R,3S)-3-methylmalic acid (compound 4b) is a synthon of 2-methyl-3-hydroxybutyrolactone.
(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol V55483 (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol 190315-43-6 (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is an analogue of purine nucleoside.
(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione V55800 (2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione 142189-87-5 (2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione is an analogue of purine nucleoside.
(2S)-2-Isopropyl-3-oxosuccinate V110284 (2S)-2-Isopropyl-3-oxosuccinate 1245945-28-1 (2S)-2-isopropyl-3-oxosuccinate ((2S)-2-isopropyl-3-oxosuccinic acid) is a nucleoside metabolite.
Contact Us