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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
(1S)-1,4-Anhydro-1-C-(2,4-difluoro-5-methylphenyl)-D-ribitol V75686 (1S)-1,4-Anhydro-1-C-(2,4-difluoro-5-methylphenyl)-D-ribitol 875302-27-5 (1S)-1,4-Anhydro-1-C-(2,4-difluoro-5-methylphenyl)-D-ribitol is an analogue of purine nucleoside.
(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol V55558 (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol 263701-23-1 (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is an analogue of purine nucleoside.
(2’,3’,5’-Tri-O-acetyl)uridine 5-carboxylic acid V55999 (2',3',5'-Tri-O-acetyl)uridine 5-carboxylic acid 174653-39-5 (2',3',5'-Tri-O-acetyl)uridine 5-carboxylic acid is an analogue of purine nucleoside.
(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol V55483 (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol 190315-43-6 (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is an analogue of purine nucleoside.
(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione V55800 (2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione 142189-87-5 (2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione is an analogue of purine nucleoside.
(R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose V75629 (R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose 6612-91-5 (R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose is an analogue of purine nucleoside.
1,2'-O-Dimethylguanosine V51796 1,2'-O-Dimethylguanosine 73667-71-7 1,2'-O-Dimethylguanosine is an analog of guanosine.
1,2,4-Triazine-3,5-dione 2-β-D-xylopyranoside V75558 1,2,4-Triazine-3,5-dione 2-β-D-xylopyranoside 93060-34-5 1,2,4-Triazine-3,5-dione 2-β-D-xylopyranoside is an analogue of purine nucleoside.
1,2-Di-O-acetyl-3,5-di-O-benzoyl-3-beta-C-methyl-D-ribofuranose V55664 1,2-Di-O-acetyl-3,5-di-O-benzoyl-3-beta-C-methyl-D-ribofuranose 22672-43-1 1,2-Di-O-acetyl-3,5-di-O-benzoyl-3-beta-C-methyl-D-ribofuranose is an analogue of purine nucleoside.
1,2-Di-O-acetyl-3,5-di-O-benzoyl-D-xylofuranose V55888 1,2-Di-O-acetyl-3,5-di-O-benzoyl-D-xylofuranose 85026-60-4 1,2-Di-O-acetyl-3,5-di-O-benzoyl-D-xylofuranose is an analogue of purine nucleoside.
1,2-Di-O-acetyl-3,5-di-O-benzyl-D-xylofuranose V75683 1,2-Di-O-acetyl-3,5-di-O-benzyl-D-xylofuranose 146986-45-0 1,2-Di-O-acetyl-3,5-di-O-benzyl-D-xylofuranose is an analogue of purine nucleoside.
1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose V55597 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose 120143-22-8 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose is an analogue of purine nucleoside.
1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-(4-methyl)benzoyl-D-ribofuranose V55453 1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-(4-methyl)benzoyl-D-ribofuranose 1612192-28-5 1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-(4-methyl)benzoyl-D-ribofuranose is an analogue of purine nucleoside.
1,2-Di-O-acetyl-5-Benzoyl-3-O-Methyl-D-ribofuranose V75710 1,2-Di-O-acetyl-5-Benzoyl-3-O-Methyl-D-ribofuranose 10300-21-7 1,2-Di-O-acetyl-5-Benzoyl-3-O-Methyl-D-ribofuranose diacetate is an analogue of purine nucleoside.
1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose V55642 1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose 159099-24-8 1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose is a ribofuranosyl nucleoside analog.
1,2-Di-O-isopropylidene-3-O-methyl-D-ribofuranose (1,2-O-Isopropylidene-3-O-Methyl-D-ribofuranose) V55393 1,2-Di-O-isopropylidene-3-O-methyl-D-ribofuranose (1,2-O-Isopropylidene-3-O-Methyl-D-ribofuranose) 35506-61-7 1,2-Di-O-isopropylidene-3-O-methyl-D-ribofuranose is an analogue of purine nucleoside.
1,2-O-Isopropylidene-5-Op-toluoyl-aD-xylofuranose V75909 1,2-O-Isopropylidene-5-Op-toluoyl-aD-xylofuranose 75096-60-5 1,2-O-Isopropylidene-5-Op-toluoyl-aD-xylofuranose is an analogue of purine nucleoside.
1,3'-Dimethylguanosine V55836 1,3'-Dimethylguanosine 74466-66-3 1,3'-Dimethylguanosine is an analogue of purine nucleoside.
1,3,5-Tri-O-benzoyl-a-D-ribofuranose (1,3,5-三苯甲酸) V55275 1,3,5-Tri-O-benzoyl-aD-ribofuranose (1,3,5-tribenzoic acid) 22224-41-5 1,3,5-Tri-O-benzoyl-aD-ribofuranose is an analogue of purine nucleoside.
1,3-Dimethyl pseudouridine V55382 1,3-Dimethyl pseudouridine 64272-68-0 1,3-Dimethyl pseudouridine is an analogue of purine nucleoside.
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