Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V108007 | (+)-7-Isomethyljasmonate | 95722-42-2 | (+)-7-isomethyljasmonic acid ester (methyl(+)-7-isojasmonic acid ester) is a metabolite in the jasmonic acid synthesis pathway. |
|
V75686 | (1S)-1,4-Anhydro-1-C-(2,4-difluoro-5-methylphenyl)-D-ribitol | 875302-27-5 | (1S)-1,4-Anhydro-1-C-(2,4-difluoro-5-methylphenyl)-D-ribitol is an analogue of purine nucleoside. |
|
V55558 | (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol | 263701-23-1 | (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is an analogue of purine nucleoside. |
|
V55999 | (2',3',5'-Tri-O-acetyl)uridine 5-carboxylic acid | 174653-39-5 | (2',3',5'-Tri-O-acetyl)uridine 5-carboxylic acid is an analogue of purine nucleoside. |
|
V110892 | (2'OMe-5'p(S)-A)pG | 2295879-58-0 | (2'OMe-5'p(S)-A)pG is a monomeric raw material that can be used for nucleic acid synthesis. |
|
V111640 | (2'OMe-5'p-m6A)pG | 1207283-40-6 | (2'OMe-5'p-m6A)pG is a monomeric raw material that can be used for nucleic acid synthesis. |
|
V111467 | (2'OMe-5'pA)pG | 62828-60-8 | (2'OMe-5'pA)pG is a monomeric raw material that can be used for nucleic acid synthesis. |
|
V111510 | (2'OMe-5'pA)pU | 2956650-76-1 | (2'OMe-5'pA)pU TEA salt is a monomeric raw material that can be used for nucleic acid synthesis. |
|
V110947 | (2'OMe-5'pG)pG | 2638447-65-9 | (2'OMe-5'pG)pG is a monomeric raw material that can be used for nucleic acid synthesis. |
|
V111662 | (2'OMe-5'pp-m6A)pG | 2956650-87-4 | (2'OMe-5'pp-m6A)pG is a monomeric raw material that can be used for nucleic acid synthesis. |
|
V111699 | (2'OMe-5'pU)pU | 57197-82-7 | (2'OMe-5'pU)pU is a monomeric raw material that can be used for nucleic acid synthesis. |
|
V110193 | (2-Amino-1-hydroxyethyl)phosphonate | 41744-58-5 | (2-Amino-1-hydroxyethyl)phosphonate (1-hydroxy-2-aminoethylphosphonic acid) is a nucleoside metabolite. |
|
V109577 | (24E)-3α,7α-Dihydroxy-5β-cholest-24-enoyl-CoA | 211363-24-5 | (24E)-3α,7α-dihydroxy-5β-cholest-24-enoyl-CoA is a nucleoside metabolite. |
|
V109733 | (25R)-3Alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA | 114987-52-9 | (25R)-3α,7α-dihydroxy-5β-cholestanyl-CoA is a coenzyme A derivative. |
|
V110189 | (25R)-3α,7α,12α-Trihydroxy-5β-cholestan-26-oyl-CoA | 21400-58-8 | (25R)-3α,7α,12α-trihydroxy-5β-cholestane-26-acyl-CoA is a nucleoside metabolite. |
|
V110190 | (25S)-3Alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA | 211505-06-5 | (25S)-3α,7α,12α-trihydroxy-5β-cholestane-26-acyl-CoA is a nucleoside metabolite. |
|
V108657 | (2R,3S)-3-Methylmalic acid | 152204-30-3 | (2R,3S)-3-methylmalic acid (compound 4b) is a synthon of 2-methyl-3-hydroxybutyrolactone. |
|
V55483 | (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol | 190315-43-6 | (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is an analogue of purine nucleoside. |
|
V55800 | (2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione | 142189-87-5 | (2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione is an analogue of purine nucleoside. |
|
V110284 | (2S)-2-Isopropyl-3-oxosuccinate | 1245945-28-1 | (2S)-2-isopropyl-3-oxosuccinate ((2S)-2-isopropyl-3-oxosuccinic acid) is a nucleoside metabolite. |