Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V75686 | (1S)-1,4-Anhydro-1-C-(2,4-difluoro-5-methylphenyl)-D-ribitol | 875302-27-5 | (1S)-1,4-Anhydro-1-C-(2,4-difluoro-5-methylphenyl)-D-ribitol is an analogue of purine nucleoside. |
|
V55558 | (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol | 263701-23-1 | (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is an analogue of purine nucleoside. |
|
V55999 | (2',3',5'-Tri-O-acetyl)uridine 5-carboxylic acid | 174653-39-5 | (2',3',5'-Tri-O-acetyl)uridine 5-carboxylic acid is an analogue of purine nucleoside. |
|
V55483 | (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol | 190315-43-6 | (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is an analogue of purine nucleoside. |
|
V55800 | (2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione | 142189-87-5 | (2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione is an analogue of purine nucleoside. |
|
V75629 | (R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose | 6612-91-5 | (R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose is an analogue of purine nucleoside. |
|
V51796 | 1,2'-O-Dimethylguanosine | 73667-71-7 | 1,2'-O-Dimethylguanosine is an analog of guanosine. |
|
V75558 | 1,2,4-Triazine-3,5-dione 2-β-D-xylopyranoside | 93060-34-5 | 1,2,4-Triazine-3,5-dione 2-β-D-xylopyranoside is an analogue of purine nucleoside. |
|
V55664 | 1,2-Di-O-acetyl-3,5-di-O-benzoyl-3-beta-C-methyl-D-ribofuranose | 22672-43-1 | 1,2-Di-O-acetyl-3,5-di-O-benzoyl-3-beta-C-methyl-D-ribofuranose is an analogue of purine nucleoside. |
|
V55888 | 1,2-Di-O-acetyl-3,5-di-O-benzoyl-D-xylofuranose | 85026-60-4 | 1,2-Di-O-acetyl-3,5-di-O-benzoyl-D-xylofuranose is an analogue of purine nucleoside. |
|
V75683 | 1,2-Di-O-acetyl-3,5-di-O-benzyl-D-xylofuranose | 146986-45-0 | 1,2-Di-O-acetyl-3,5-di-O-benzyl-D-xylofuranose is an analogue of purine nucleoside. |
|
V55597 | 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose | 120143-22-8 | 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose is an analogue of purine nucleoside. |
|
V55453 | 1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-(4-methyl)benzoyl-D-ribofuranose | 1612192-28-5 | 1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-(4-methyl)benzoyl-D-ribofuranose is an analogue of purine nucleoside. |
|
V75710 | 1,2-Di-O-acetyl-5-Benzoyl-3-O-Methyl-D-ribofuranose | 10300-21-7 | 1,2-Di-O-acetyl-5-Benzoyl-3-O-Methyl-D-ribofuranose diacetate is an analogue of purine nucleoside. |
|
V55642 | 1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose | 159099-24-8 | 1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose is a ribofuranosyl nucleoside analog. |
|
V55393 | 1,2-Di-O-isopropylidene-3-O-methyl-D-ribofuranose (1,2-O-Isopropylidene-3-O-Methyl-D-ribofuranose) | 35506-61-7 | 1,2-Di-O-isopropylidene-3-O-methyl-D-ribofuranose is an analogue of purine nucleoside. |
|
V75909 | 1,2-O-Isopropylidene-5-Op-toluoyl-aD-xylofuranose | 75096-60-5 | 1,2-O-Isopropylidene-5-Op-toluoyl-aD-xylofuranose is an analogue of purine nucleoside. |
|
V55836 | 1,3'-Dimethylguanosine | 74466-66-3 | 1,3'-Dimethylguanosine is an analogue of purine nucleoside. |
|
V55275 | 1,3,5-Tri-O-benzoyl-aD-ribofuranose (1,3,5-tribenzoic acid) | 22224-41-5 | 1,3,5-Tri-O-benzoyl-aD-ribofuranose is an analogue of purine nucleoside. |
|
V55382 | 1,3-Dimethyl pseudouridine | 64272-68-0 | 1,3-Dimethyl pseudouridine is an analogue of purine nucleoside. |
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