Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
V75686 (1S)-1,4-Anhydro-1-C-(2,4-difluoro-5-methylphenyl)-D-ribitol 875302-27-5
V55558 (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol 263701-23-1
V55999 (2',3',5'-Tri-O-acetyl)uridine 5-carboxylic acid 174653-39-5
V55483 (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol 190315-43-6
V55800 (2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione 142189-87-5
V75629 (R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose 6612-91-5
V51796 1,2'-O-Dimethylguanosine 73667-71-7 1,2'-O-Dimethylguanosine is an analog of guanosine.
V75558 1,2,4-Triazine-3,5-dione 2-β-D-xylopyranoside 93060-34-5
V55664 1,2-Di-O-acetyl-3,5-di-O-benzoyl-3-beta-C-methyl-D-ribofuranose 22672-43-1
V55888 1,2-Di-O-acetyl-3,5-di-O-benzoyl-D-xylofuranose 85026-60-4
V75683 1,2-Di-O-acetyl-3,5-di-O-benzyl-D-xylofuranose 146986-45-0
V55597 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose 120143-22-8
V55453 1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-(4-methyl)benzoyl-D-ribofuranose 1612192-28-5
V75710 1,2-Di-O-acetyl-5-Benzoyl-3-O-Methyl-D-ribofuranose 10300-21-7
V55642 1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose 159099-24-8
V55393 1,2-Di-O-isopropylidene-3-O-methyl-D-ribofuranose (1,2-O-Isopropylidene-3-O-Methyl-D-ribofuranose) 35506-61-7
V75909 1,2-O-Isopropylidene-5-Op-toluoyl-aD-xylofuranose 75096-60-5
V55836 1,3'-Dimethylguanosine 74466-66-3
V55275 1,3,5-Tri-O-benzoyl-aD-ribofuranose (1,3,5-tribenzoic acid) 22224-41-5
V55382 1,3-Dimethyl pseudouridine 64272-68-0
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