Dopamine Receptor

Dopamine Receptor

In the central nervous system (CNS) of vertebrates, dopamine receptors are a class of G protein-coupled receptors that are widely distributed. The main endogenous ligand for dopamine receptors is the neurotransmitter dopamine. Numerous neurological functions, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as the modulation of neuroendocrine signaling, are associated with dopamine receptors.Numerous neuropsychiatric disorders have abnormal dopamine receptor signaling and dopaminergic nerve function at their core. Dopamine receptors are therefore typical neurologic drug targets; psychostimulants are typically indirect agonists of dopamine receptors, whereas antipsychotics are frequently dopamine receptor antagonists. Dopamine receptors come in at least five different subtypes: D1, D2, D3, D4, and D5. The D2, D3, and D4 dopamine receptors are members of the D2-like family, whereas the D1 and D5 receptors belong to the D1-like family.

Dopamine Receptor related products

Structure Cat No. Product Name CAS No. Product Description
V19599 (-)-Quinpirole HCl 85798-08-9 Quinpirole HCl [(-)-LY 171555] is a highly potent psychoactive drug and research chemical which acts as a high affinity and selective D₂ and D₃ receptor agonist.
V71727 (R)-Preclamol ((+)-3-PPP) 85976-54-1
V71759 (R)-Preclamol hydrochloride ((+)-3-PPP hydrochloride) 89874-80-6
V71721 (Rac)-PF-06256142 1609580-97-3
V71728 (Rac)-Razpipadon (PW0464) 1643462-93-4
V71221 (Rac)-Rotigotine (N-0437) 92206-54-7
V71718 (Rac)-Tavapadon ((Rac)-PF-06649751; (Rac)-CVL-751) 1643462-64-9
V71732 [18F]-Labeled L-dopa precursor 1614253-58-5
V9846 A-381393 726174-00-1 A-381393 is a novel and potent agonist of the dopamine D4 receptor.
V71753 A-412997 dihydrochloride 1347744-96-0
V71745 A-77636 778546-51-3
V71716 A68930 hydrochloride 130465-39-3
V9995 ABT-724 70006-24-5 ABT-724 isa novel,potent and highly selective dopamine D4 receptor agonist with an EC50 of 12.4 nM.
V40042 ABT-724 trihydrochloride 587870-77-7 ABT-724 trihydrochloride is a novel, potent and highly selective dopamine D4 receptor agonist with an EC50 of 12.4 nM.
V1255 Alizapride HCl 59338-87-3 Alizapride HCl (Limican; Plitican; Vergentan; Superan; Alizaprida; Litican; MS-5080), the hydrochloride salt of alizapride which is a medication used for the theropy of nausea and vomiting, is a potent dopamine receptor antagonist with prokinetic and antiemetic effects.
V1257 Amantadine HCl 665-66-7 Amantadine HCl (EXP-105-1; GP 38026; ADS5102; Influenol; Midantan; Midantane; Mydantane; NSC 83653; Symadine; Symmetrel; Trivaline; Virasol; Viregyt; Virofral; Virosol),the hydrochloride salt of amantadine, is an approved medication used to treat or prevent infections of the respiratory tract caused by a certain virus.
V1250 Amfebutamone HCl 31677-93-7 Amfebutamone HCl (Bupropion, Wellbutrin, Zyban; BW-323; NSC315851; NSC-315851), the hydrochloride salt of Amfebutamone, is a potent and selective norepinephrine-dopamine reuptake inhibitor used as an antidepressant and for smoking cessation.
V1271 Amisulpride (DAN 2163) 71675-85-9 Amisulpride (Solian; Amazeo; Amipride; Amival; Soltus; Aminosultopride; DAN-2163; DAN2163; Deniban; Amisulprida; Sulpitac; Sulprix) is a potent and atypical antipsychotic medication used to treat psychosis in schizophrenia and episodes of mania in bipolar disorders.
V11154 Amisulpride HCl 81342-13-4 Amisulpride HCl (Barhemsys; Solian; Amazeo; Aminosultopride; Amipride; Amival; Deniban; Amisulprida; Soltus; DAN-2163; Sulpitac; Sulprix), the hydrochloride salt of Amisulpride, is an atypical antipsychotic medication approved for treating psychosis in schizophrenia and episodes of mania in bipolar disorders.
V71769 Amisulpride-d5 (amisulpride d5) 1216626-17-3
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