A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit.At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
Structure | Cat No. | Product Name | CAS No. | Product Description |
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V88758 | (10E,12E)-9-Oxo-10,12-octadecadienoic acid | 54232-58-5 | (10E,12E)-9-Oxo-10,12-octadecadienoic acid (9-oxo-ODA) is a PPARα agonist isolated from the basidiomycete Gomphus floccosus. |
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V91048 | (4S)-(+)-Ascochin | 935699-58-4 | (4S)-(+)-Ascochin is an antifungal agent that inhibits Microbotryum violaceum, Phytophthora infestans and Septoria tritici. |
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V90886 | (E)-4-Methyl-5-styrylbenzene-1,3-diol | 2407559-34-4 | (E)-4-Methyl-5-styrylbenzene-1,3-diol (Compound III) is an antifungal agent extracted from Dracaena cochinchinensis (Lour.) SC Chen. |
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V103811 | (Gly0.8Nap0.2)20 | (Gly0.8Nap0.2)20 is a dual-targeting compound against fungal membranes and DNA. | |
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V102712 | (RS)-Sakuranetin | 520-29-6 | (RS)-Sakuranetin is the racemate of Sakuranetin. |
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V102647 | (±)-Dunnione | 521-49-3 | (±)-Dunnione (SL 11010) is a compound with broad-spectrum antifungal activity that acts by initiating redox cycling. |
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V105650 | 10-Undecenoic acid (copper) | 35322-29-3 | Copper 10-undecenoate (undecylenate) was used as the starting reagent for the synthesis of the pheromone (11Z)-hexadecenal. |
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V97796 | 13-Hydroxy-9-octadecenoic acid | 324575-43-1 | 13-Hydroxy-9-octadecenoic acid is a hydroxyunsaturated fatty acid (HUFA) with antifungal activity. |
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V94976 | 14α-Demethylase-IN-1 | 3026164-55-3 | 14α-Demethylase-IN-1 (Compound 2e) is a 14α-demethylase inhibitor and can be used as an antifungal agent. |
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V89726 | 2′-Hydroxychalcone | 1214-47-7 | 2'-Hydroxychalcone is a hydroxy derivative of chalcone with anticancer activity. |
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V106715 | 2,3,5-Tri-O-benzyl-D-ribose | 54623-25-5 | 2,3,5-Tri-O-benzyl-D-ribose (Compound 1) is a potent inhibitor of chitin synthase (CHS) from Botrytis cinerea with IC50 of 1.8 μM. |
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V105685 | 2,3-Dichloro-1,4-naphthoquinone | 117-80-6 | 2,3-Dichloro-1,4-naphthoquinone is an effective fungicide. |
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V97799 | 3-GlcA-28-AraRhaxyl-medicagenate | 128192-15-4 | 3-GlcA-28-AraRhaxyl-medicagenate is an insect toxin belonging to the saponin family. |
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V105943 | 6-O-Methylreticulol | 24350-93-4 | 6-O-Methylreticulin (compound 1a) is an isocoumarin isolated from an endophytic fungus of the mangrove plant Avicennia marina in the Pearl River Estuary in southern China. |
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V102421 | 6-Prenylindole | 23158-16-9 | 6-Isopentenyl indole is an antifungal agent that can be isolated from Streptomyces sp. |
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V91114 | 8-Acetylverrucarin L | 77101-88-3 | 8-Acetylverrucarin L (Verrucarin L acetate) is a mycotoxin with antitumor and antibacterial activities. |
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V102830 | 9-OxoOTrE | 125559-74-2 | 9-OxoOTrE (9-KOTrE) is an antifungal agent that exhibits inhibitory activity against B. cinerea, C. herbarum, P. infestans, and P. parasitica via an electrophilic mechanism. |
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V91076 | Acremine I | 1110661-29-4 | Acremine I is a fungicide and a metabolite of the endophytic fungus Acremonium byssoides. |
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V101746 | AEC5 | 2035042-31-8 | AEC5 is a lipopeptide with antifungal activity against Cryptococcus neoformans infection. |
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V101926 | Alternariol, methyl ether | 26894-49-5 | Alternaria methyl ether is a common mycotoxin in spoiled grains, which has mutagenic and carcinogenic effects in vitro. |