A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit.At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V88758 | (10E,12E)-9-Oxo-10,12-octadecadienoic acid | 54232-58-5 | (10E,12E)-9-Oxo-10,12-octadecadienoic acid (9-oxo-ODA) is a PPARα agonist isolated from the basidiomycete Gomphus floccosus. | |
V91048 | (4S)-(+)-Ascochin | 935699-58-4 | (4S)-(+)-Ascochin is an antifungal agent that inhibits Microbotryum violaceum, Phytophthora infestans and Septoria tritici. | |
V90886 | (E)-4-Methyl-5-styrylbenzene-1,3-diol | 2407559-34-4 | (E)-4-Methyl-5-styrylbenzene-1,3-diol (Compound III) is an antifungal agent extracted from Dracaena cochinchinensis (Lour.) SC Chen. | |
V89726 | 2′-Hydroxychalcone | 1214-47-7 | 2'-Hydroxychalcone is a hydroxy derivative of chalcone with anticancer activity. | |
V91114 | 8-Acetylverrucarin L | 77101-88-3 | 8-Acetylverrucarin L (Verrucarin L acetate) is a mycotoxin with antitumor and antibacterial activities. | |
V91076 | Acremine I | 1110661-29-4 | Acremine I is a fungicide and a metabolite of the endophytic fungus Acremonium byssoides. | |
V91774 | Amycolatopsin B | 2209112-97-8 | Amycolatopsin B (compound 2) is a glycosylated polyketide macrolide with antifungal activity that was isolated from the soil isolate Amycolatopsis sp. MST-108494. | |
V88250 | Ansatrienin A | 82189-03-5 | Ansatrienin A is an antifungal antibiotic isolated from Streptomyces collinus. | |
V51010 | Antibacterial agent 67 | 2488900-01-0 | The inhibitory activity of antibacterial agent 67 (IC50 = 0.03 μM) as an enzyme inhibitor of acid dehydrogenase was significantly higher than that of fluorophosphotidol (IC50 = 4.40 μM). | |
V91120 | Antibiotic WB | 247919-66-0 | Antibiotic WB is an antibiotic with antifungal activity, which can be isolated from soil fungus strain 38. | |
V92168 | Antifungal agent 100 | 2975157-18-5 | Antifungal agent 100 (compound 3i) exhibited significant antifungal activity against S. sclerotiorum with an EC50 value of 0.33 mg/L. | |
V90771 | Antifungal agent 91 | Antifungal agent 91 (compound 1) is a dihydroflavonol isolated from the leaves of Artocarpus elasticus. | ||
V11513 | APX001A (Manogepix; E 1210) | 936339-60-5 | APX001A (Manogepix, E1210) is a first-in-class,broad-spectrum and orally bioactive inhibitor of the fungal protein Gwt1 (GPI-anchored wall transfer protein 1) in the glycosylphosphatidylinositol (GPI) biosynthesis pathway. | |
V91012 | AS-2077715 | 1637356-98-9 | AS-2077715 is an antifungal agent that exhibits inhibitory activity against Trichophyton spp. | |
V91775 | Burnettramic acid A | 2334483-46-2 | Burnettramic acid A is an antibiotic isolated from Aspergillus burnettii. | |
V91050 | Chaetoviridin A | 128252-98-2 | Chaetoviridin A exhibits antifungal activity against a variety of plant pathogens and inhibits the growth of Verticillium dahliae through cell necrosis and hyphal deformation, thereby increasing the sensitivity of Verticillium dahliae to stress and improving the emergence rate and plant height of cotton. | |
V92149 | Cinnamon bark oil, from Cinnamonum zeylanicum Blume | 8015-91-6 | Cinnamon bark oil, from Cinnamonum zeylanicum Blume, is a mycotoxicant that has toxic effects on fungi that cause respiratory mycoses. | |
V91034 | Concanamycin C | 81552-34-3 | Concanamycin C inhibits the proliferation of mouse spleen lymphocytes. | |
V60102 | (R)-(+)-Corypalmine | 13063-54-2 | ||
V89191 | Elsinochrome A | 24568-67-0 | Elsinochrome A is a perylenequinone photosensitizer that can generate reactive oxygen species under light excitation, inducing apoptosis and autophagy. |