Angiotensin II serves as the ligand for the class of G protein-coupled receptors known as angiotensin receptors. They play a crucial role in the renin-angiotensin system as they are involved in the signal transduction of the main effector hormone, angiotensin II's, vasoconstricting stimulus. Angiotensin II, their primary ligand, has a similar affinity for the AT1 and AT2 receptors. The angiotensin receptor that has been most thoroughly characterized is AT1. The fetus and newborn have a higher concentration of AT2 receptors. The AT3 and AT4 receptors are additional understudied subtypes.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V75301 | 1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone | 120693-52-9 | Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9 is an antagonist of angiotensin II receptor (IC50=48.2 μM). |
|
V77338 | [Sar1, Ile8]-Angiotensin II TFA (AngiotensinII TFA; Angiotensin 2 TFA) | [Sar1, Ile8]-Angiotensin II (TFA) is a polypeptide that has multiple effects in vascular smooth muscle cells such as contraction of normal arteries, hypertrophy or proliferation of cultured cells or diseased blood vessels, etc. | |
|
V75293 | [Tyr(P)4] Angiotensin II | 129785-85-9 | [Tyr(P)4] Angiotensin II is a polypeptide that has multiple effects in vascular smooth muscle cells such as contraction of normal arteries, hypertrophy or proliferation of cultured cells or diseased blood vessels, etc. |
|
V11300 | Angiotensin acetate | 58-49-1 | Angiotensin II 5-valine is an agonist of the angiotensin receptor. |
|
V77261 | Angiotensin I/II (1-5) (TFA) | Angiotensin I/II 1-5 TFA is a polypeptide consisting of 1-5 amino acid (AA)s, converted from angiotensin I/II peptide. | |
|
V77260 | Angiotensin I/II (1-6) (TFA) | Angiotensin I/II (1-6) TFA contains 1-6 amino acid (AA)s and is converted from angiotensin I/II peptide. | |
|
V77259 | Angiotensin II (3-8), human TFA | Angiotensin II (3-8), human (TFA) is a less active angiotensin AT1 receptor agonist (activator). | |
|
V77258 | Angiotensin III, human, mouse TFA | Angiotensin III, human, mouse (TFA) is an angiotensin. | |
|
V75290 | Angiotensinogen (1-13) (human) | 82048-97-3 | Angiotensinogen (1-13) (human) is a fragment of the renin substrate angiotensinogen, a naturally occurring renin substrate and the precursor of all angiotensin peptides |
|
V79495 | Antihypertensive agent 2 | Antihypertensive agent 2 (Compound 4g) is an antihypertensive agent. | |
|
V78008 | Antihypertensive agent 3 | Antihypertensive agent 3 (compound 4a) is an angiotensin II receptor 1 antagonist. | |
|
V75296 | AT1R antagonist 1 | 2848719-80-0 | AT1R antagonist 1 (compound 10) is a potent AT1R selective ligand. |
|
V75291 | AT1R antagonist 2 | 2848719-76-4 | AT1R antagonist 2 (compound 6) is a potent AT1R selective ligand. |
|
V11927 | AVE 0991 | 304462-19-9 | AVE-0991 is a novel, orally bioactive non-peptide mimic and high affinity agonist of angiotensin-(1-7) (IC50 = 21 nM) with important cardioprotective bioactivity. |
|
V11930 | AVE-0991 sodium | 306288-04-0 | AVE0991 sodium, the sodium salt ofAVE-0991, is a novel, orally bioactivenon-peptide mimic and high affinity agonist of angiotensin-(1-7) with an IC50 of 21 nM. |
|
V29052 | Azilsartan medoxomil monopotassium (TAK 491) | 863031-24-7 | Azilsartan medoxomil monopotassium (TAK-491; TAK491; Edarbi), the monopotassium salt ofAzilsartan medoxomil which is a prodrug of azilsartan, is an angiotensin II receptor (AT1) type 1 antagonistapproved as an anti-hypertensive medication to lower blood pressure. |
|
V12233 | Azilsartan mepixetil | 1596357-16-2 | Azilsartan mepixetil isa prodrug ofazilsartan which is an antagonist of angiotensin II receptor with antihypertensive, renal and cardioprotective effects. |
|
V75289 | Azilsartan mepixetil potassium (QR-01019K) | 2153458-32-1 | Azilsartan mepixetil potassium (QR-01019K) is an angiotensin II receptor antagonist. |
|
V75280 | Azilsartan methyl ester | 147403-52-9 | Azilsartanmethylester is an analogue of Azilsartan, an angiotensin II receptor blocker (antagonist) that plays important roles in hypertension. |
|
V75285 | Azilsartan mopivabil | 2271428-31-8 | Azilsartan mopivabil is a potent antagonist of angiotensin II receptor. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
