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Angiotensin Receptor

Angiotensin Receptor

Angiotensin II serves as the ligand for the class of G protein-coupled receptors known as angiotensin receptors. They play a crucial role in the renin-angiotensin system as they are involved in the signal transduction of the main effector hormone, angiotensin II's, vasoconstricting stimulus. Angiotensin II, their primary ligand, has a similar affinity for the AT1 and AT2 receptors. The angiotensin receptor that has been most thoroughly characterized is AT1. The fetus and newborn have a higher concentration of AT2 receptors. The AT3 and AT4 receptors are additional understudied subtypes.

Angiotensin Receptor related products

Structure Cat No. Product Name CAS No. Product Description
1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone V75301 1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone 120693-52-9 Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9 is an antagonist of angiotensin II receptor (IC50=48.2 μM).
[Sar1, Ile8]-Angiotensin II TFA (AngiotensinII TFA; Angiotensin 2 TFA) V77338 [Sar1, Ile8]-Angiotensin II TFA (AngiotensinII TFA; Angiotensin 2 TFA) [Sar1, Ile8]-Angiotensin II (TFA) is a polypeptide that has multiple effects in vascular smooth muscle cells such as contraction of normal arteries, hypertrophy or proliferation of cultured cells or diseased blood vessels, etc.
[Tyr(P)4] Angiotensin II V75293 [Tyr(P)4] Angiotensin II 129785-85-9 [Tyr(P)4] Angiotensin II is a polypeptide that has multiple effects in vascular smooth muscle cells such as contraction of normal arteries, hypertrophy or proliferation of cultured cells or diseased blood vessels, etc.
Angiotensin I/II (1-5) (TFA) V77261 Angiotensin I/II (1-5) (TFA) Angiotensin I/II 1-5 TFA is a polypeptide consisting of 1-5 amino acid (AA)s, converted from angiotensin I/II peptide.
Angiotensin I/II (1-6) (TFA) V77260 Angiotensin I/II (1-6) (TFA) Angiotensin I/II (1-6) TFA contains 1-6 amino acid (AA)s and is converted from angiotensin I/II peptide.
Angiotensin II (3-8), human TFA V77259 Angiotensin II (3-8), human TFA Angiotensin II (3-8), human (TFA) is a less active angiotensin AT1 receptor agonist (activator).
Angiotensin III, human, mouse TFA V77258 Angiotensin III, human, mouse TFA Angiotensin III, human, mouse (TFA) is an angiotensin.
Angiotensinogen (1-13) (human) V75290 Angiotensinogen (1-13) (human) 82048-97-3 Angiotensinogen (1-13) (human) is a fragment of the renin substrate angiotensinogen, a naturally occurring renin substrate and the precursor of all angiotensin peptides
Antihypertensive agent 2 V79495 Antihypertensive agent 2 Antihypertensive agent 2 (Compound 4g) is an antihypertensive agent.
Antihypertensive agent 3 V78008 Antihypertensive agent 3 Antihypertensive agent 3 (compound 4a) is an angiotensin II receptor 1 antagonist.
AT1R antagonist 1 V75296 AT1R antagonist 1 2848719-80-0 AT1R antagonist 1 (compound 10) is a potent AT1R selective ligand.
AT1R antagonist 2 V75291 AT1R antagonist 2 2848719-76-4 AT1R antagonist 2 (compound 6) is a potent AT1R selective ligand.
AT1R antagonist 3 V86527 AT1R antagonist 3 AT1R antagonist 3 (Compound 1) is an antagonist of angiotensin II type 1 receptor (AT1R) and an inhibitor of L-type calcium channel CaV1.
AT2 receptor ligand-1 V84474 AT2 receptor ligand-1
AVE 0991 V11927 AVE 0991 304462-19-9 AVE-0991 is a novel, orally bioactive non-peptide mimic and high affinity agonist of angiotensin-(1-7) (IC50 = 21 nM) with important cardioprotective bioactivity.
Azilsartan mepixetil potassium (QR-01019K) V75289 Azilsartan mepixetil potassium (QR-01019K) 2153458-32-1 Azilsartan mepixetil potassium (QR-01019K) is an angiotensin II receptor antagonist.
Azilsartan methyl ester V75280 Azilsartan methyl ester 147403-52-9 Azilsartanmethylester is an analogue of Azilsartan, an angiotensin II receptor blocker (antagonist) that plays important roles in hypertension.
Azilsartan mopivabil V75285 Azilsartan mopivabil 2271428-31-8 Azilsartan mopivabil is a potent antagonist of angiotensin II receptor.
Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) V77186 Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) is a polypeptide containing 32 amino acid (AA)s.
Buloxibutid (M24; AT2 receptor agonist C21) V11787 AT2 Agonist C21 (M24) 477775-14-7 AT2 Agonist C21(M-24) is a novel, potent and selective agonist of angiotensin AT2 receptors with Ki values of 0.4 nM and >10 µM for the AT2 receptor and AT1 receptor, respectively.
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