yingweiwo

S1P Receptor

S1P Receptor

S1P Receptor related products

Structure Cat No. Product Name CAS No. Product Description
CAY10444 V10510 CAY10444 298186-80-8 CAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist.
JTE-013 HCl V23005 JTE-013 HCl 383150-41-2 JTE-013 HCl is a novelm potent, selective antagonist of sphingosine-1-phosphate 2 (S1P2) receptor, with IC50 of 17 and 22 nM, respectively, (IC50 >10 µM for for binding to human S1P1 and S1P3).
PF-429242 V4144 PF-429242 947303-87-9 PF429242 (PF-429242) is a novel, potent, reversible and competitive S1P [sterol regulatory element-binding protein (SREBP) site 1 protease] inhibitor with an IC50 of 170 nM.
PF-543 V1504 PF-543 1415562-82-1 PF-543 (also called PF543; PF 543; Sphingosine Kinase 1 Inhibitor II) is a novel cell-permeable and sphingosine-competitive inhibitor of SphK1 with potential antitumor activity.
SKI II V1503 SKI II 312636-16-1 SKI II (also known as SphK-I2; Sphingosine kinase inhibitor II; SK-III) is a potent, highly selective, non-lipid and non-ATP-competitive sphingosine kinase (SphK) inhibitor with potential anticancer activity.
伏波酯 V15276 Phorbol 12-myristate 13-acetate (PMA) 16561-29-8 Phorbol 12-myristate 13-acetate (PMA) is a novel and potent protein kinase C (PKC) agonist with the potential for the treatment of acute myeloid leukemia and cardiac fibrosis.
奥帕尼布;奥格尼布 V1506 Opaganib (ABC294640) 915385-81-8 Opaganib (formerly known as ABC294640; ABC-294640; Trade name Yeliva) is a novel, potent, selective, competitive and orally bioavailable aryladamantane analog and selective sphingosine kinase-2 (SphK2) inhibitor with potential anticancer activity.
奥扎莫德 V1507 Ozanimod (RPC1063) 1306760-87-1 Ozanimod (formerly RPC-1063; trade name Zeposia) is a selective and orally bioavailable S1P Receptor 1 modulator that has been approved as an immunomodulatory medication for the treatment of relapsing multiple sclerosis and ulcerative colitis.
珀奈莫德 V22749 Ponesimod 854107-55-4 Ponesimod (formerly known as ACT-128800; ACT128800; Ponvory) is an orally bioavailable and selective agonist of sphingosine-1-phosphate receptor 1 (S1PR1, S1P1) approved in 2021 by FDA to treat relapsing forms of multiple sclerosis.
盐酸芬戈莫德 V1502 Fingolimod (FTY720) HCl 162359-56-0 Fingolimod HCl (formerly FTY-720; FTY 720; Gilenia and Gilenya), an FDA approved drug for the treatment of Multiple sclerosis, is a S1P (sphingosine 1-phosphate) antagonist with potential antineoplastic activity.
辛波莫德 V1505 Siponimod (BAF312) 1230487-00-9 Siponimod (BAF-312; WHO-9491; NVP-BAF-312; Mayzent) is anovel, potent and orally bioavailable S1P receptor modulator with immunomodulating activity.
辛波莫德富马酸盐 V17399 Siponimod fumarate (BAF312) 1234627-85-0 Siponimod (BAF-312) hemifumarate is a potent, selective sphingosine-1-phosphate (S1P) receptor modulator.
Contact Us