Structure | Cat No. | Product Name | CAS No. | Product Description |
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V4243 | AZD6482 S-isomer | 1173900-37-2 | AZD6482 S-isomer, is an isomer of AZD6482 which is a novel, potent, selective and ATP competitive PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and is 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ in cell-free assays. |
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V4171 | BAY-524 | 1445830-39-6 | BAY-524is a novel and potent Bub1 inhibitor with anIC50of 450 nM for human Bub1 in the presence of 2 mM ATP. |
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V4168 | BAY-598 R-isomer | 1906920-28-2 | BAY-598 R-isomer (R-BAY598) is the R-enantiomer of BAY589 which is a peptide-competitive SMYD2 inhibitor with antineoplastic activity. |
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V4164 | BAY-677 | 2117404-84-7 | BAY-677 is an inactive and negative control for BAY-678. |
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V4129 | BLU-782 | 2141955-96-4 | BLU-782 has been discontinued. |
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V4137 | GSK-2336805 | 1256390-53-0 | GSK-2336805 (also known as GSK-805; GSK2336805; JNJ-56914845) is a novel and potent inhibitor of HCV NS5A. |
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V4075 | LGD-4033 | 1165910-22-4 | LGD-4033 (also known as VK-5211 and Ligandrol) isa novel, potent and selective androgen receptor modulator (SARM) and is being investigated by Ligand Pharmaceuticals for treatment of conditions such as muscle wasting and osteoporosis. |
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V4291 | MK-6240 | 1841078-87-2 | MK-6240 is a novel positron emission tomography (PET) tracer fordetecting neurofibrillary tangles (NFTs). |
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V4015 | ML-290 | 1482500-76-4 | ML-290, a 2-acetamido-N-phenylbenzamide analog, is a novel potent, selective and orally bioactive agonist of the relaxin/insulin-like family peptide receptor (RXFP1)and an activator of anti-fibrotic genes with anEC50of 94 nM. |
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V4010 | ML-7 | 109376-83-2 | ML-7 (ML7) is a potent Myosin light chain kinase (MLCK) inhibitor with IC50of 300 nM and IC50>10 μM for MLCK and TRPC6 channel respectively. |
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V4023 | ML132 | 1230628-71-3 | ML132 (also known as NCGC 00185682) is a potent and selectivecaspase 1inhibitor with anIC50of 0.316 nM. |
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V4225 | NSC 77674 | 737-86-0 | NSC77674 (also known as PIH or Pyridoxal isonicotinoyl hydrazone) is is a novel, potent, lipophilic, nontoxic, iron-chelating agent that shows high iron chelation efficacy both in vitro in cell culture models and in vivo in rats and mice. |
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V4132 | PROTAC-VHL-ligand | 1448297-52-6 | PROTAC-VHL-ligand or Protein degrader 1 is a novel and potent small molecule ligand forVHL (Von Hippel-Lindau), anE3 ligasewhich has been targeted by many PROTACs (proteolysis-targeting chimeras) degarders. |
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V4062 | Protein degrader 1 TFA | 1631137-51-3 | Protein degrader 1 TFA (trifluoroacetic acid salt) is a novel and potent small molecule ligand forVHL (Von Hippel-Lindau), anE3 ligasewhich has been targeted in many PROTACs (proteolysis-targeting chimeras). |
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V4042 | R(+)-SKF-38393A | 81702-42-3 | R(+)-SKF-38393A (the R-isomer of SKF3839A) is a novel potent and selective dopamine D1 receptor agonist with IC50 of 110 nM,the (+)-enantiomer is the active isomer. |
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V4043 | SKF-77434 HBr | 300561-58-4 | SKF-77434 HBr is a novel potent and selective dopamine D1-like receptor partial agonist. |
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V4041 | SKF38393 | 67287-49-4 | SKF38393 (also known as SKF-38393A) is a novel potent and selective dopamine D1 receptor agonist with IC50 of 110 nM,the (+)-enantiomer is the active isomer. |
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V4210 | Emiglitate | 80879-63-6 | Emiglitate (also known as BAY o 1248) is a novel, potent, selective and competitive inhibitor ofα-glucoside hydrolase. |
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V4161 | Diroximel fumarate | 1577222-14-0 | Diroximel fumarate (also known as ALKS 8700) is a novel compound that is taken orally and rapidly converted into monomethyl fumarate (MMF). |
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V4273 | Bucladesine (Dibutyryl-cAMP) | 362-74-3 | Bucladesine (DC2797; DC-2797; Dibutyryl-cAMP) is a potent and cell-permeable PKA activator and a cAMP analog that mimics the action of endogenous cAMP. |