Serine (Ser) proteases are enzymes that catalyze the hydrolysis of specific peptide bonds in their substrates, and one of the amino acids in the enzyme's active site is always a serine. The trypsin family and the subtilisin family are two families that have received particular attention in research. The process of blood clotting, protein digestion, cell signaling, inflammation, and protein processing are just a few of the numerous cellular and extracellular functions that serine proteases are essential for. A threonine residue is present in the active site of a family of proteolytic enzymes known as thronine (Thr) proteases. Although the catalytic subunits of the proteasome are the prototype members of this class of enzymes, the active site geometry and mechanism of acyltransferases were convergently evolved.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V4173 | BAY-1816032 | 1891087-61-8 | BAY-1816032 (BAY1816032) is a novel, potent and oral bioavailable inhibitor ofBUB1 (budding uninhibited by benzimidazoles 1) kinase with anticancer effects. |
|
V22131 | Hepln-13 | 64369-13-7 | Hepln-13 (Hepln13; Hepln 13) is a novel, orally bioactive and potent hepsin inhibitor (IC50 = 0.33 µM) with potential anticancer activity. |
|
V2313 | HPK1-IN-2 | 2056122-11-1 | HPK1-IN-2 is a novel,potent and orally activehematopoietic progenitor kinase-1 (HPK1)inhibitor (IC50<0.05 µΜ) with antitumor activity. |
|
V2897 | ML281 | 1404437-62-2 | ML-281,a quinoxalinone derivative, is a novel, potent and selective STK33 inhibitor with IC50 value of 14 nM. |
|
V14713 | SGC GAK 1 | 2226517-76-4 | SGC-GAK-1 is a potent and specific cyclin G-associated kinase (GAK) inhibitor (antagonist) with Ki of 3.1 nM. |
|
V3015 | STK16-IN-1 | 1223001-53-3 | STK16-IN-1 is a novel and highly selective ATP competitive inhibitor of STK16 kinase with an IC50 of 295 nM. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
