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    Desonide
    Desonide

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    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V1706
    CAS #: 638-94-8Purity ≥98%

    Description: Desonide, a nonfluorinated corticosteroid anti-inflammatory drug, is a low potency topical corticosteroid with anti-inflammatory activities. Desonide is the generic name of a low potency topical corticosteroid that has been available since the 1970s. It is primarily used for the treatment of atopic dermatitis (eczema), seborrheic dermatitis, psoriasis and contact dermatitis in both adults and children and has a fairly good safety profile and is available as a cream, ointment, lotion, and, since September 19, 2006, as a foam under the tradename Verdeso Foam. 

    References: Expert Opin Investig Drugs. 2008 Jul;17(7):1097-104; J Drugs Dermatol. 2010 Apr;9(4):324-9.

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    Molecular Weight (MW)416.51
    FormulaC24H32O6
    CAS No.638-94-8
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Solubility (In vitro)DMSO: 83 mg/mL (199.3 mM)
    Water:<1 mg/mL
    Ethanol: 30 mg/mL (72.02 mM)
    Solubility (In vivo)2% DMSO+49% PEG 300+dd H2O: 10mg/mL  
    Other info

    Chemical Name: (6aR,7S,8aS,8bS,11aR)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one

    InChi Key: WBGKWQHBNHJJPZ-QHDHGWJCSA-N

    InChi Code: InChI=1S/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15?,16?,17-,19+,20?,22-,23-,24+/m0/s1

    SMILES Code: O=C(C=C[[email protected]@]12C)C=C1CCC(C2[[email protected]@H](O)C[[email protected]@]34C)C3C[[email protected]]5([H])[[email protected]@]4(C(CO)=O)OC(C)(C)O5


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