| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V10412 | AEW-541 cis-isomer (NVP-AEW541) | 475489-16-8 | NVP-AEW541cis-isomer (also known as AEW541 cis-isomer), the cis-isomer of AEW541 is a novel and potent inhibitor of IGF-1R/InsR with IC50 of 150 nM/140 nM in cell-free assays, it has greater potency and selectivity for IGF-1R in a cell-based assay. |
|
V0626 | AG-1024 (Tyrphostin; Tyrphostin AG1024) | 65678-07-1 | AG-1024 (also called Tyrphostin or Tyrphostin AG1024) is a potent and selective inhibitor of IGF-1R (insulin-like growth factor-1) with potential antitumor activity. |
|
V0625 | BMS-536924 (CS0117; BMS 536924) | 468740-43-4 | BMS-536924 (also called CS-0117; BMS536924; CS0117) is a novel, potent and ATP-competitivesmall molecule inhibitor of IGF-1R/IR with potential anticancer activity. |
|
V5122 | Chromeceptin | 331859-86-0 | Chromeceptin (94G6) is an inhibitor (blocker/antagonist) of the IGF signaling pathway. |
|
V0623 | GSK1904529A (GSK-4529; GSK-1904529A; GSK 4529) | 1089283-49-7 | GSK1904529A (also known as GSK-4529; GSK-1904529A; GSK 4529) is a novel, potent and selective inhibitor of IGF-1R (insulin-like growth factor-1 receptor) and IR (insulin receptor) with potential anticancer activity. |
|
V88054 | IGF-1R inhibitor-3 | 1227753-12-9 | IGF-1R inhibitor-3 (Compound C11) is an allosteric inhibitor of insulin-like growth factor receptor 1 kinase (IGF-1R) with IC50 of 0.2 μM. |
|
V7093 | NBI-31772 | 374620-70-9 | NBI-31772 (NBI31772) is a novel and potent non-peptide inhibitor of insulin-like growth factor-1 binding protein (IGFBP)with Kd values are 1 - 24 nM for all six human subtypes. |
|
V0624 | NVP-ADW742 | 475488-23-4 | NVP-ADW742 (also known as ADW-742; ADW 742; GSK552602A; GSK-552602A) is a novel, potent and selective IGF-1R inhibitor with potential antitumor activity. |
|
V0622 | NVP-AEW541 | 475488-34-7 | NVP-AEW541 (also known as AEW541; AEW-541) is a novel, potent and selective inhibitor of IGF-1R/InsR with potential antineoplastic activity. |
|
V0621 | OSI-906 (Linsitinib) | 867160-71-2 | Linsitinib (formerly OSI-906;OSI 906) is a firs-in-class,ATP-competitive and orally bioavailable dual inhibitor of and insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF-1R) with potential antitumor activity. |
|
V0628 | Picropodophyllin (Picropodophyllotoxin, AXL-1717 or PPP) | 477-47-4 | Picropodophyllin (also known as Picropodophyllotoxin, AXL1717 or PPP), a naturally occuring cyclolignan alkaloid isolated from the mayapple plant family, is a novel, potent, orally bioavailable and selective small molecule inhibitor of the IGF-1R with potential antineoplastic activity. |
|
V0627 | PQ 401 | 196868-63-0 | PQ401 (PQ-401) is a novel, potent and selective inhibitor of IGF-1R (insulin-like growth factor-1 receptor) with potential antineoplastic activity. |
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