The catecholamines, in particular norepinephrine and epinephrine, are targets of the G protein-coupled receptor class known as adrenergic receptors. These receptors are found on numerous cells, and when a catecholamine binds to one of these receptors, the sympathetic nervous system is typically stimulated. The fight-or-flight response is controlled by the sympathetic nervous system, which causes the eye pupils to dilate, the body to mobilize energy, and the blood supply to skeletal muscle to be diverted from non-essential organs.There are numerous subtypes of the two main groups of adrenergic receptors, and. The receptor subtypes 1 and 2 exist. There are three subtypes of receptors: 1, 2, and 3. They are all associated with Gs proteins, which are associated with adenylate cyclase. Thus, antagonist binding increases the level of the second messenger cAMP inside of the cell. The cAMP-dependent protein kinase (PKA), one of cAMP's downstream effectors, mediates some intracellular processes after hormone binding.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V78868 | Nefazodone-d6 hydrochloride (BMY-13754-d6; MJ-13754-1-d6) | Nefazodone-d6 ( HCl) is the deuterated form of Nefazodone HCl. | |
|
V71282 | Neldazosin | 109713-79-3 | Neldazosin is a potent α1-adrenoceptor antagonist. |
|
V71336 | Nipradolol (KT 210; K 351; Hypadil) | 81486-22-8 | Nipradolol (KT-210; K-351) is a potent α-1-adrenergic receptor antagonist (blocker). |
|
V1122 | Noradrenaline bitartrate monohydrate | 108341-18-0 | Noradrenaline bitartrate monohydrate (Levophed; NSC169106; Arterenol bitartrate; Noradrenalin bitartrate; NSC-169106; Levarterenol bitartrate monohydrate), the bitartrate salt and hydrated form ofNoradrenaline, is a direct-acting alpha-adrenergic receptors agonist/stimulator. |
|
V71326 | Norfenefrine hydrochloride | 4779-94-6 | Norfenefrine HCl is an orally bioactive, endogenous alpha-adrenergic agonist indicated for treating stress urinary incontinence in women. |
|
V26836 | Octopamine HCl | 770-05-8 | Octopamine ((±)-p-Octopamine) HCl is a biological monoamine structurally related to norepinephrine and functions as a neurohormone, neuromodulator, and neurotransmitter in invertebrates. |
|
V27027 | Oxprenolol hydrochloride | 6452-73-9 | Oxprenolol HCl (Ba-39089 hydrochloride) is a novel and potent beta blocker with intrinsic sympathomimetic activity. |
|
V71307 | Oxprenolol-d7 hydrochloride (Ba 39089-d7) | 1189649-47-5 | Oxprenolol-d7 ( HCl) is the deuterated form of Oxprenolol HCl. |
|
V71351 | Oxyfedrine | 15687-41-9 | Oxyfedrine, a vasodilator, is an orally bioactive β-adrenoceptor (β-adrenoreceptor) agonist. |
|
V1115 | Oxymetazoline HCl | 2315-02-8 | Oxymetazoline HCl (Rhinofrenol; Afrin; Ocuclear; Drixine; Nezeril; Sinerol; Hazol; Nafrine; Navasin), the hydrochloride salt of oxymetazoline, is an imidazole-based α1 and α2 adrenergic receptor agonist. |
|
V71275 | Phenoxybenzamine (benzyl-2,3,4,5,6-d5) (hydrochloride) | 1398065-71-8 | Phenoxybenzamine (benzyl-2,3,4,5,6-d5) ( HCl) is the deuterated form of Phenoxybenzamine HCl. |
|
V1145 | Phenoxybenzamine HCl | 63-92-3 | Phenoxybenzamine HCl (formerly NSC-37448; NSC37448; Dibenzyline, NCI-C01661, NCIC01661; NCI-c01661), the hydrochloride salt of Phenoxybenzamine, is a potent, non-specific, irreversible alpha-adrenergic receptor antagonist with antihypertensive effects. |
|
V71264 | Phenoxybenzamine-d5 (phenoxybenzamine-d5) | 1309283-11-1 | Phenoxybenzamine-d5 is the deuterium labelled form of Phenoxybenzamine. |
|
V71265 | Phenoxybenzamine-d5 hydrochloride | 1329838-45-0 | Phenoxybenzamine-d5 ( HCl) is the deuterium labelled form of Phenoxybenzamine HCl. |
|
V1140 | Phentolamine Mesylate | 65-28-1 | Phentolamine Mesylate (OraVerse, Regitine mesylate, Regitine, Regityn, Rogitine, Z-Max), the mesylate/mesilate/methanesulfonate salt of Phentolamine, is a reversible and nonselective alpha-adrenergic receptor antagonist with antihypertensive effects. |
|
V1130 | Phenylephrine HCl | 61-76-7 | Phenylephrine HCl (Metaoxedrine chloride; NCIc-55641; NCI c55641; Neosympatol; Oftalfrine; Mezaton; Neo Synephrine; Neo-Synephrine),the hydrochloride salt of Phenylephrine, is a potent and selective α1-adrenergic receptor agonist that is primarily used as a decongestant. |
|
V71272 | Phenylethanolamine A | 1346746-81-3 | Phenylethanolamine A is a beta-adrenergic agonist. |
|
V71349 | Phenylethanolamine A-d3 | 2507994-61-6 | Phenylethanolamine A-d3 is a deuterated form of Phenylethanolamine A. |
|
V0047 | Piperoxan hydrochloride (Benodaine hydrochloride) | 135-87-5 | Piperoxan hydrochloride(also known as PiperoxanHCl, or benodaine) is a novel, selective and potent α2adrenoceptor antagonist. |
|
V71315 | Practolol-d7 (practolol d7) | 2714414-11-4 | Practolol-d7 is the deuterated form of Practolol. |
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