| Size | Price | Stock | Qty |
|---|---|---|---|
| 2g |
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| 5g |
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| 10g |
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| 25g |
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| Other Sizes |
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| Targets |
Human Endogenous Metabolite; α2-adrenergic receptor
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|---|---|
| ln Vitro |
Octopamine is involved in a number of physiological processes: (a) it acts as a neuromodulator, controlling the desensitization of sensory inputs, arousal, initiation, and maintenance of complex behaviors like learning and memory; (b) it acts as a neurotransmitter, controlling the activity of endocrine glands; and (c) it acts as a neurohormone, causing the mobilization of fats and carbohydrates. In order to cause its effects, octopamine binds to particular proteins that are members of the G protein-coupled receptor superfamily and have seven transmembrane domains in common structurally[1].
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| References | |
| Additional Infomation |
(R)-octopamine is an octopamine. It is an enantiomer of a (S)-octopamine.
p-Hydroxyphenylethanolamine has been reported in Aplysia californica, Fascaplysinopsis reticulata, and other organisms with data available. An alpha-adrenergic sympathomimetic amine, biosynthesized from tyramine in the CNS and platelets and also in invertebrate nervous systems. It is used to treat hypotension and as a cardiotonic. The natural D(-) form is more potent than the L(+) form in producing cardiovascular adrenergic responses. It is also a neurotransmitter in some invertebrates. See also: Octopamine (annotation moved to). |
| Molecular Formula |
C8H12CLNO2
|
|---|---|
| Molecular Weight |
189.63
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| Exact Mass |
189.055
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| Elemental Analysis |
C, 50.67; H, 6.38; Cl, 18.69; N, 7.39; O, 16.87
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| CAS # |
770-05-8
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| Related CAS # |
Octopamine-d4 hydrochloride; 1219803-62-9
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| PubChem CID |
440266
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| Appearance |
White to off-white solid powder
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| Boiling Point |
360.7ºC at 760 mmHg
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| Melting Point |
~170 °C (dec.)(lit.)
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| Flash Point |
172ºC
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| LogP |
1.886
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| Hydrogen Bond Donor Count |
3
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| Hydrogen Bond Acceptor Count |
3
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| Rotatable Bond Count |
2
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| Heavy Atom Count |
11
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| Complexity |
111
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| Defined Atom Stereocenter Count |
1
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| SMILES |
Cl[H].O([H])C([H])(C([H])([H])N([H])[H])C1C([H])=C([H])C(=C([H])C=1[H])O[H]
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| InChi Key |
PUMZXCBVHLCWQG-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C8H11NO2.ClH/c9-5-8(11)6-1-3-7(10)4-2-6;/h1-4,8,10-11H,5,9H2;1H
|
| Chemical Name |
4-(2-amino-1-hydroxyethyl)phenol;hydrochloride
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| Synonyms |
Octopamine Hydrochloride; Octopamine Hydrochloride salt; Octopamine HCl; Octopamine HCl salt
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO: ≥ 100 mg/mL (~527.3 mM)
H2O: ≥ 50 mg/mL (~263.7 mM) |
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 100 mg/mL (527.31 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.2734 mL | 26.3671 mL | 52.7343 mL | |
| 5 mM | 1.0547 mL | 5.2734 mL | 10.5469 mL | |
| 10 mM | 0.5273 mL | 2.6367 mL | 5.2734 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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