The ion channel known as the calcium channel exhibits selective permeability to calcium ions. Although there are ligand-gated calcium channels as well, it is sometimes referred to as a voltage-dependent calcium channel. Even though the concentration of Na+ outside of cells is 70 times higher than that of Ca2+, voltage-gated calcium (CaV) channels catalyze a rapid, highly selective influx of Ca2+ into cells. A side effect of some calcium channel blockers is that they slow your heart rate, which helps to lower blood pressure, treat angina, and regulate irregular heartbeats.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V1701 | Mometasone furoate | 83919-23-7 | Mometasone Furoate (formerly Sch 32088; Sch32088;SCH-32088)is a potent glucocorticoid receptor agonist and an approved anti-inflammatory drug used as a topical formulation to reduce inflammation of the skin or in the airways. |
|
V0748 | Nicardipine HCl (RS69216; YC93; Antagonil, Dagan, Flusemide) | 54527-84-3 | Nicardipine HCl (formerly YC-93, RS-69216; YC93; trade names Cardene, Dagan,Antagonil, Flusemide), the hydrochloride salt of nicardipine, is a dihydropyridine/DHP class of calcium-channel blocker (CCB) with anti-hypertensive activity. |
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V33654 | Nifedipine D6 | 1188266-14-9 | Nifedipine D6 is the hexa-deuterated form of Nifedipine (Bay-1040; Cordipin;BAY-a-1040; Corinfar) which is an approved antihypertensive drug of thedihydropyridine calcium channel blocker (CCB) class. |
|
V0920 | Nisoldipine | 63675-72-9 | Nisoldipine (BAY-K-5552;Bay K-5552, Sular, Baymycard, Nisocor, Syscor) is a novel CCB-calcium channel blocker of the dihydropyridine (DHP)class with vasodilating and antihypertensive effects. |
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V3671 | NNC 55-0396 | 357400-13-6 | NNC 55-0396 dihydrochloride salt, an analog of mibefradil, is a novel, potent and highly selective T-type calcium channel blocker which displays IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells. |
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V26632 | NP118809 | 41332-24-5 | NP-118809 is a N-type calcium channel blocker. |
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V12267 | NS-638 | 150493-34-8 | NS-638 is a non-peptide small molecule with the property of blocking Ca2+-ion channels. |
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V1696 | O4I1 | 175135-47-4 | O4I1 (O4-I1; O4I-1; O4I 1) is a novel and potent inducer of Oct3/4 (POU5F1 and Oct4)with potential usefulness as a regenerative medicine. |
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V1695 | O4I2 | 165682-93-9 | O4I2 is a potent Oct3/4 inducer. |
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V29507 | Praeruptorin C | 72463-77-5 | Praeruptorin C(Pra-C) is a natural product that has been widely used as an antioxidant and a calcium antagonist for the treatment of various diseases. |
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V29319 | Praeruptorin E | 78478-28-1 | Praeruptorin Eis a naturally occurring coumarin derivative extracted from P. |
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V1698 | Prednisolone | 50-24-8 | Prednisolone (AKOS-016010152; AK-115681; Predsol; Pediapred) is an approved medication acting as a potent and synthetic glucocorticoid with anti-inflammatory and immunomodulatory properties. |
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V1699 | Prednisone | 53-03-2 | Prednisone(also known as Dehydrocortisone; trade names: Adasone; Deltasone, Liquid Pred, Orasone, among others) is an approved glucocorticoid medication mostly used to suppress the immune system and decrease inflammation in conditions such as asthma, COPD, and rheumatologic diseases. |
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V13298 | Protopine | 130-86-9 | Protopine (Corydinine) is an isoquinoline alkaloid and a specific, reversible and competitive inhibitor of acetylcholinesterase. |
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V0368 | Ranolazine 2HCl (RS-43285; CVT-303) | 95635-56-6 | Ranolazine 2HCl (known also as Ranolazine diHydrochloride), the diHCl salt of ranolzaine (RS43285; CVT303),is aan anti-angina drug which acts as a potent calcium uptake inhibitor via the sodium/calcium channel, it isused to treat chronic angina. |
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V2210 | SR33805 | 121345-64-0 | SR33805 is a novel and potent antagonist of Ca2+ channel with EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively, and it blocks L-type but not T-type Ca2+ channels. |
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V3759 | Suvecaltamide (MK-8998) | 953778-58-0 | Suvecaltamide (MK8998; compound 33;MK-8998) is a novel potent and selective antagonist of the T-type calcium channel that is being investigated as a potential new therapeutic for the treatment of schizophrenia. |
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V1691 | Tezacaftor (VX-661) | 1152311-62-0 | Tezacaftor (formerly VX-661; VX661; VX 661;trade name:Symdeko) is a second F508del CFTR corrector with antifibrotic effects and is alsoone of three components in thefixed-dose combination medication (cocktail: Elexacaftor/tezacaftor/ivacaftor, Trikafta and Kaftrio) used in patients who have cystic fibrosis with a F508del mutation. |
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V1710 | Triamcinolone Acetonide | 76-25-5 | Triamcinolone acetonide (Acetospan; Adcortyl A; AllerNaze;Kenalone; Nasacort; Aristocort; Aristoderm. |
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V27972 | Verapamil | 52-53-9 | Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent, orally bioactive, first-generation P-glycoprotein (P-gp) inhibitor. |
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