Calcium Channel

Calcium Channel

The ion channel known as the calcium channel exhibits selective permeability to calcium ions. Although there are ligand-gated calcium channels as well, it is sometimes referred to as a voltage-dependent calcium channel. Even though the concentration of Na+ outside of cells is 70 times higher than that of Ca2+, voltage-gated calcium (CaV) channels catalyze a rapid, highly selective influx of Ca2+ into cells. A side effect of some calcium channel blockers is that they slow your heart rate, which helps to lower blood pressure, treat angina, and regulate irregular heartbeats.

Calcium Channel related products

Structure Cat No. Product Name CAS No. Product Description
V71513 Menthol-d4 1217765-02-0 Menthol-d4 is the deuterium labelled form of Menthol.
V33725 Mibefradil dihydrochloride 116666-63-8 Mibefradil dihydrochloride (Ro 40-5967; trade name: Posicor), thedihydrochloride salt of miberfradil, is a CCB/calcium channel blocker with anti-hypertensive activity.
V71538 MMK1 271246-66-3 MMK1 is a potent and specific human formyl peptide receptor-like 1 (FPRL-1/FPR2) agonist/activator with EC50s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively.
V80794 MMK1 TFA MMK1 TFA is a potent and specific human formyl peptide receptor-like 1 (FPRL-1/FPR2) agonist/activator with EC50s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively.
V80860 Myoregulin (MLN peptide) Myoregulin (MLN peptide) is a member of the regulin family.
V80861 Myoregulin TFA (MLN peptide TFA) Myoregulin (MLN peptide) TFA is a member of the regulin family.
V80865 Myr-TAT-CBD3 Myr-TAT-CBD3 is a CRMP2-CaV2.2 interaction inhibitor.
V71516 N-Desalkylflurazepam (Norfludiazepam) 2886-65-9 N-Desalkylflurazepam (Norfludiazepam) is a long-acting metabolite of benzodiazepines such as Flurazepam.
V71536 Ned-K 2250019-90-8 Ned-K is a niacin adenine dinucleotide phosphate (NAADP) antagonist.
V71508 Nemadipine-A 54280-71-6 Nemadipine-A is a specific inhibitor of the EGL-19 Ca2+ channel.
V71505 Norverapamil-d7 hydrochloride ((±)-Norverapamil-d7 (hydrochloride); D591-d7 (hydrochloride)) 1216413-74-9 Norverapamil-d7 ( HCl) is a deuterium labelled form of Norverapamil.
V76662 PACAP-38 (31-38), human, mouse, rat TFA PACAP-38 (31-38), human, mouse, rat TFA is a PAC1 receptor agonist/activator.
V81035 Palmitoylglycine-d31 (N-palmitoylglycine-d31) Palmitoylglycine-d31 is the deuterated form of Palmitoylglycine.
V80048 PptT-IN-4 PptT-IN-4 (Compound 3a) is a PptT inhibitor (IC50= 0.71 μM).
V81217 Propiverine-d7 hydrochloride (propiverine d7 hydrochloride) Propiverine-d7 ( HCl) is the deuterated form of Propiverine HCl.
V71490 ProTx-I 484598-35-8 ProTx-I, a toxin derived from Thrixopelma pruriens, is a potent and specific CaV3.1 channel blocker with IC50s of 0.2 μM and 31.8 μM for hCAV3.1 and hCaV3.2, respectively.
V71485 Ranolazine-d3 (ranolazine d3) 1054624-77-9 Ranolazine-d3 is the deuterated form of Ranolazine.
V71506 Rp-8-Br-cGMPS sodium salt (Rp-8-bromo-Cyclic GMPS sodium salt) 208445-06-1 Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is an effective Ca2+-ATPase activator.
V71469 Ruthenium red (Ruthenium red; Ammoniated ruthenium oxychloride) 11103-72-3 Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye extensively used for observation of cells, tissues and vegetative bacteria under electron microscopy (EM).
V78416 RyR2 stabilizer-1 RyR2 stabilizer-1 (compound 12a) is a potent RyR2 stabilizer and SERCA2a activator with EC50s of 2.7 μM and 383 nM for RyR2 and SERCA2, respectively.
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