Calcium Channel

Calcium Channel

The ion channel known as the calcium channel exhibits selective permeability to calcium ions. Although there are ligand-gated calcium channels as well, it is sometimes referred to as a voltage-dependent calcium channel. Even though the concentration of Na+ outside of cells is 70 times higher than that of Ca2+, voltage-gated calcium (CaV) channels catalyze a rapid, highly selective influx of Ca2+ into cells. A side effect of some calcium channel blockers is that they slow your heart rate, which helps to lower blood pressure, treat angina, and regulate irregular heartbeats.

Calcium Channel related products

Structure Cat No. Product Name CAS No. Product Description
V81828 ω-Conotoxin Bu8 ω-Conotoxin Bu8 is an ω-conotoxin consisting of 25 amino acid (AA) residues and 3 disulfide bridges.
V71502 ω-Conotoxin CnVIIA 760212-36-0 ω-Conotoxin CnVIIA is a 27-amino acid (AA) neuropeptide toxin and an N-type calcium current blocker.
V71523 ω-Conotoxin CVIA 325164-06-5 ω-Conotoxin CVIA is a 27-amino acid (AA) neuropeptide toxin and a voltage-sensitive calcium channel blocker.
V71530 ω-Conotoxin CVID (Leconotide; AM336; CNSB004) 247207-64-3 ω-Conotoxin CVID (Leconotide, AM336, CNSB004) blocks neuronal voltage-sensitive calcium channels.
V81829 ω-Conotoxin CVIE ω-Conotoxin CVIE is a voltage-gated calcium channel (Ca v 2.2) selective inhibitor.
V81830 ω-Conotoxin CVIF ω-Conotoxin CVIF is a selective Cav2.2 channel inhibitor (antagonist) with IC50 of 34.3 nM in isolated rat DRG neurons.
V81831 ω-Conotoxin FVIA ω-Conotoxin FVIA is an N-type calcium channel (Ca v 2.2) inhibitor.
V57221 ω-Conotoxin GVIA TFA ω-Conotoxin GVIA TFA is an N-type calcium channel (Ca2+ channel) inhibitor.
V81832 ω-conotoxin MoVIA ω-conotoxin MoVIA is a potent and specific Cav2.2 inhibitor (antagonist) with IC50 of 0.33 μM in the SH-SY5Y fluorescence hCav2.2 assay.
V42130 ω-Conotoxin MVIIC TFA (ω-Conotoxin MVIIC TFA) ω-Conotoxin MVIIC TFA is an N- and P/Q-type calcium channel (Ca2+ channel) blocker that can significantly block 11-keto-βboswellic acid-mediated inhibition of glutamate release.
V81833 ω-Conotoxin MVIID (SNX-238) ω-Conotoxin MVIID (SNX-238) is a conopeptide that blocks ω-Conotoxin-GVIA-sensitive high-threshold Ca2+ currents in fish retinal ganglion cells.
V71499 ω-Conotoxin SO3 441284-32-8 ω-Conotoxin SO3 is a blocker of N-type voltage-sensitive calcium channels.
V71526 ω-Grammotoxin SIA (GrTx; ω-GsTx SIA) 152617-90-8 ω-Grammotoxin SIA (GrTx) is an inhibitor (blocker/antagonist) of P/Q and N-type voltage-gated Calcium Channels.
V71497 ω-Hexatoxin-Hv1a (ω-ACTX-Hv1; ω-Atracotoxin-HV1) 193981-10-1 ω-Hexatoxin-Hv1a is a neurotoxin extracted from the venomous spider (Hadronyche versuta).
V81834 ω-Tbo-IT1 ω-Tbo-IT1 is a bioactive peptide toxin extracted from the venom of Tibellus oblongus.
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