New7

Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD
GPCR & G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase Adrenergic Receptor Angiotensin Receptor APJ Bombesin Receptor Bradykinin Receptor cAMP Cannabinoid Receptor CaSR CCK receptor CCR CGRP Receptor CRFR CXCR Dopamine Receptor EBI2 Endothelin Receptor Formyl Peptide Receptor Free Fatty Acid Receptor G protein-coupled Bile Acid Receptor GCGR GHSR GLP Receptor Glucagon Receptor GnRH Receptor GPCR19 GPR GPR109A Guanylate Cyclase Hedgehog(Smoothened) ROCK Histamine Receptor ICMT Leukotriene Receptor LPA Receptor LPL Receptor LTR mAChR Melanocortin Receptor Melatonin Receptor mGluR Motilin Receptor MRGPR MT Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor NPY receptor Opioid Receptor OX Receptor Oxytocin Receptor P2Y Receptor PAFR PAR PKD PKG Prostaglandin Receptor Ras RGS Protein S1P Receptor SGLT Sigma Receptor Somatostatin Receptor TAAR TSH Receptor Urotensin Receptor Vasopressin Receptor

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V4505	JNJ-54175446	1627902-21-9	JNJ-54175446 (JNJ54175446) is a novel, potent and selective brain penetrantP2X7 receptorantagonist being developed for treating major depressive disorder.
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V4512	JNJ4796	2241664-16-2	JNJ4796 is a novel, potent and oral bioactive fusion inhibitor of influenza virus, which neutralizes influenza A group 1 viruses by inhibiting hemagglutinin (HA)-mediated fusion.
V4789	K-Ras G12C-IN-1	1629265-17-3	K-Ras G12C-IN-1 is a novel, potent and irreversible/covalent inhibitor of K-Ras protein with G12C mutation.
V4788	K-Ras G12C-IN-2	1629267-75-9	K-Ras G12C-IN-2 is a novel, potent and irreversible/covalent inhibitor of K-Rasprotein with G12C mutation.
V4790	K-Ras G12C-IN-3	1629268-19-4	K-Ras G12C-IN-3 is a novel, potent and irreversible/covalent inhibitor of K-Rasprotein with G12C mutation.
V4838	KKI 5	97145-43-2	KKI 5 is, a synthetic peptide, is a novel and potent serine protease inhibitor that inhibits kallikrein and plasmin.
V4784	KRas G12C inhibitor 1	2158297-28-8	KRAS G12C inhibitor 1 is a novel and potent inhibitor of KRAS.
V4785	KRas G12C inhibitor 2	2206735-61-5	KRAS G12C inhibitor 2 is a novel and potent inhibitor of KRAS.
V4786	KRas G12C inhibitor 3	2206735-75-1	KRAS G12C inhibitor 3 is a novel and potent inhibitor of KRAS.
V4783	KRas G12C inhibitor 4	2206736-07-2	KRas G12C inhibitor 4 is a novel and potent inhibitor of KRAS.
V4787	KRas G12C inhibitor 5	2158297-63-1	KRAS G12C inhibitor 5 is a novel and potent inhibitor of KRAS.
V4801	KX-01-191	2211903-84-1	KX-01-191 (compound 5c′) is a tin reagent precursor.
V5159	L 601920-0 (Methyl-3β-hydroxycholenate)	20231-57-6	Methyl-3β-hydroxycholenate is a ROR gamma modulator.
V4973	Lanosterol	79-63-0	Lanosterol, a naturally-occurring triterpenoid derivative, is a key imtermediate in the biosynthesis of Cholesterol.
V5128	Lck inhibitor II	918870-43-6	Lck inhibitor II is a novel, potent, cell-permeable, ATP competitive amd tri-substituted pyrimidine that acts as a highly potent Lck (lymphocyte specific kinase) inhibitor with the potential for cancer treatment.
V4664	LEQ-506	1057677-92-5	LEQ-506 (also known as NVP-LEQ506) is a novel, orally bioavailable and second-generation small-molecule inhibitor ofsmoothened(Smo) withIC50s of 2 and 4 nM in human and mouse, respectively.
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V4844	LY 178002	107889-32-7	LY 178002 is a novel and potent inhibitor of5-lipoxygenase,phospholipase A2withIC50of 0.6 μM for 5-1ipoxygenase, it inhibits cellular production of LTB4 by human polymorphonuclear leukocytes, and shows relatively weak inhibition oncyclooxygenase.
V4842	LY 222306	154446-98-7	LY 222306 is an inhibitor (blocker/antagonist) of glycinamide ribonucleotide formyltransferase ((GARFT)) with Ki of 0.77 nM.