| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V4729 | MEK-IN-1 | 870600-45-6 | MEK-IN-1 is a MEK inhibitor from patent WO2008076415A1. |
|
V5098 | Methyl protodioscin (NSC-698790) | 54522-52-0 | Methyl protodioscin (also known as NSC-698790; Smilax saponin B) is a novel furostanol bisglycoside with potent antitumor properties; it is able to reduce proliferation and cause cell cycle arrest. |
|
V4722 | MG 1 | 148274-76-4 | MG 1 (MG-1) is a novel and potent α1adrenergic receptorantagonist identified using the quantitative structure-activity relationship model. |
|
V4899 | Mibampator | 375345-95-2 | Mibampator (formerly also known as LY-451395) is a novel, potent and highly selective AMPA receptor potentiator being developed for agitation/aggression in Alzheimers disease. |
|
V4940 | MRS-2179 | 101204-49-3 | MRS-2179 (MRS2179) is a novel, potent and competitive P2Y1 receptor antagonist with anti-thrombotic/anti-platelet effects. |
|
V4692 | MT-3014 | 1332727-40-8 | MT-3014,a pyrazolo[1,5-a]pyrimidine derivative, is a novel, potent, highly selective and brain-penetrantphosphodiesterase 10A (PDE 10A)inhibitor, withIC50s of 0.062 nM and 0.09 nM for human PDE 10A and bovine PDE 10A, respectively. |
|
V4693 | MT-7716 | 610323-32-5 | MT-7716 (also known as W-212393) is a novel, potent and selective non-peptidenociceptin receptor (NOP)agonist with the potential to be used for treatment of alcohol abuse and relapse prevention. |
|
V4695 | MTDIA HCl | 1399840-35-7 | MTDIA (also known as MT-DADMe-ImmA and Methylthio-DADMe-Immucillin A) is a novel and potent inhibitor of human 5-methylthioadenosine phosphorylase (MTAP) with aKiof 90 pM. |
|
V4827 | Myriocin | 35891-70-4 | Myriocin (formerly also known as antibiotic ISP-1 and thermozymocidin), a fungal metabolite and an atypical amino acid and an antibiotic isolated fromMyriococcum albomyces,Isaria sinclairiandMycelia sterilia, is a novel and potent inhibitor ofserine-palmitoyl-transferase (SPT)which is a key enzyme in de novo synthesis of sphingolipids. |
|
V5030 | Nalmefene HCl | 58895-64-0 | Nalmefene HCl (originally known as nalmetrene; trade name Selincro) is a potent opioid antagonist used primarily in the management of alcohol dependence. |
|
V4674 | Narlaprevir | 865466-24-6 | Narlaprevir (formerly also known as SCH-900518) is a novel, potent, selective, orally bioavailable and second generation inhibitor of HCV NS3 protease with Ki value of 6 nM and EC90=40 nM. |
|
V4757 | Naxagolide | 88058-88-2 | Naxagolide is a novel and potent dopamine D2-receptor agonist used for treatment of extrapyramidal disorders. |
|
V5062 | NED-3238 | 2389062-09-1 | NED3238 is a novel, highly potent and selective inhibitor of human arginase I and II with IC50 values of 1.3 and 8.1 nM, respectively. |
|
V4818 | Nevanimibe HCl | 133825-81-7 | Nevanimibe HCl (also known as PD-132301 hydrochloride and ATR-101 hydrochloride), the hydrochloride salt ofNevanimibe, is a novel, selective and potent acyl-coenzyme A: cholesterol O-acyltransferase 1 (ACAT1) inhibitor with anEC50of 9 nM. |
|
V4724 | Nitroxazepine | 47439-36-1 | Nitroxazepine, a serotonin-norepinephrine reuptake inhibitor, is a potent tricyclic antidepressant (TCA) for the treatment of depression. |
|
V5021 | NSC 601980 analog | 91757-46-9 | NSC 601980 analog, an analog of NSC601980, shows antitumor activity in the yeast screening experiment, which can inhibit cell proliferation in the COLO 205 and HT29 with Log GI 50 of -6.6 and -6.9 respectively. |
|
V5038 | NSC-305787 HCl | 53868-26-1 | NSC305787 HCl, the hydrochloride salt ofNSC305787, is a novel, potent and selectivesmall molecule inhibitor of ezrin with a Kdof 5.85 μM, it inhibits the phosphorylation of ezrin caused by PKCΙ with an IC50of 8.3 μM, and has antitumor activity. |
|
V5024 | NSC16168 | 6837-93-0 | NSC16168 is a novel, potent and specific inhibitor of ERCC1-XPF with an IC50value of 0.42 μM. |
|
V5040 | NSC232003 | 1905453-18-0 | NSC232003 is a novel, highly potent and cell-permeable UHRF1 inhibitor, which inhibits DNA methylation in vitro and disrupts DNMT1/UHRF1 interactions at a cellular level. |
|
V5035 | NSC601980 | NSC601980 exhibits anticancer activity in the yeast screening experiment, which can inhibit cell proliferation in the COLO 205 and HT29 with Log GI 50 of -6.6 and -6.9 respectively. |
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