| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V4795 | DT-061 | 1809427-19-7 | DT-061 (also known as DT061; SMAP) is a novel, potent and orally bioavailable activator of PP2A (protein phosphatase 2A) with anticancer effects. |
|
V4730 | EBI-1051 | 1801896-05-8 | EBI-1051 is a selective, orally bioavailable MEK inhibitor (antagonist) with IC50 of 3.9 nM. |
|
V4953 | Emicerfont | 786701-13-1 | Emicerfont (also known asGW876008) is a novel and potent corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50of 66 nM. |
|
V5004 | ERB-196 (WAY-202196) | 550997-55-2 | ERB-196 (ERB196; WAY-202196) is a novel, potent, orally bioactive and nonsteroidal selective estrogen receptor-β (ERβ) agonist with the potential to be used for the treatment or prevention of severe sepsis. |
|
V4901 | Erteberel | 533884-09-2 | Erteberel (also known as LY500307) is a novel, potent and selective estrogen receptor beta (ERβ) inhibitor withKiandEC50of 1.54 nM and 3.61 nM, respectively. |
|
V4792 | FGTI-2734 | 1247018-19-4 | FGTI-2734 is a novel and potent RAS C-terminal mimetic dualfarnesyl transferase (FT)andgeranylgeranyl transferase-1 (GGT)inhibitor that thwarts Mutant KRAS-Driven Patient-Derived Pancreatic Tumors withIC50s of 250 nM and 520 nM forFTandGGT, respectively. |
|
V5084 | Fiacitabine (NSC-382097; FIAC; FOAC) | 69123-90-6 | Fiacitabine(also known as NSC 382097; DRG-0077) is a novel, potent and selective inhibitior of DNA replication of herpes simplex virus(HSV) with IC50 values of 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively. |
|
V5195 | Fumonisin B1 | 116355-83-0 | Fumonisin B1 (HSDB7077; RT-013063; HSDB-7077; RT013063)is a naturally occuring mycotoxin/fungal metabolite isolated fromFusarium moniliforme. |
|
V4781 | G-744 | 1346669-54-2 | G-744 is a novel, highly potent, selective and orally bioavailableBtkinhibitor with anIC50of 2 nM. |
|
V4527 | GDC-0339 | 1428569-85-0 | GDC-0339 (GDC0339) is a novel, orally bioavailable, potent and selective small molecule pan-Pim kinase inhibitor with anticancer activity. |
|
V4520 | GDC-0834 | 1133432-49-1 | GDC-0834 (R-enantiomer) is a novel, potent and selectiveBTKinhibitor with an in vitroIC50of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivoIC50of 1.1 and 5.6 μM in mouse and rat, respectively. |
|
V4522 | GDC-0834 S-enantiomer | 1133432-50-4 | GDC-0834 S-enantiomeris the S-isomer ofGDC-0834. |
|
V4819 | Gemcabene | 183293-82-5 | Gemcabene (formerly known as PD-72953) is a potent and first-in-class lipid-lowering agent that lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity. |
|
V4684 | Gemilukast | 1232861-58-3 | Gemilukast (formerly also known as ONO-6950) is a novel, potent and orally bioavailable dual CysLT1 and CysLT2 (cysteinyl leukotriene 1 and 2) antagonist withIC50sof 1.7, 25 nM for human CysLT1and CysLT2, respectively. |
|
V5143 | Giripladib (PLX-695) | 865200-20-0 | Giripladib (formerly known as PLX695) is a novel and potent cPLA2-specific inhibitor. |
|
V4551 | GNE-049 | 1936421-41-8 | GNE-049 is a novel, highly potent and selective CBP/p300 bromodomaininhibitor with anIC50of 1.1 nM in TR-FRET assay. |
|
V4555 | GNE-0946 | 1677667-24-1 | GNE-0946 (GNE0946) is a novel, potent and selectiveRORγ( RORc) inverseagonist with the potential to be used fortreating autoimmune diseases. |
|
V4543 | GNE-220 | 1199590-75-4 | GNE-220 is a novel, potent and selective inhibitor ofMAP4K4with anIC50of 7 nM. |
|
V4544 | GNE-220 HCl | 2448286-21-1 | GNE-220 HCl is a novel, potent and selective inhibitor ofMAP4K4with anIC50of 7 nM. |
|
V4548 | GNE-4997 | 1705602-02-3 | GNE-4997 is a potent and specific inhibitor of interleukin 2-induced T-cell kinase (ITK) with Ki of 0.09 nM. |
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