Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.

Liposome related products

Structure Cat No. Product Name CAS No. Product Description
V73430 DOPE-GA 228706-30-7 DOPE-GA may be utilized to prepare liposomes for drug delivery studies.
V73431 DOPE-NHS 1010188-79-0 DOPE-NHS is a linker.
V41367 DOTMA 104872-42-6 DOTMA is atetra-methylated DOTA analog used as a non viral vector for gene therapy, in miRNA delivery system and promotes liposome-cell membrane interactions.
V74077 DPPG sodium 200880-41-7 DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing long-chain (16:0) palmitic acid inserted into the sn-1 and sn-2 positions.
V73415 DSPE-alkyne 2933227-70-2 DSPE-alkyne is a phospholipid.
V73473 DSPE-Biotin 2933185-14-7 DSPE-Biotin is a lipid.
V73447 DSPE-glutaric acid 1009838-54-3 DSPE-glutaric acid is a lipid.
V74068 DSPE-Mal 1360858-99-6 DSPE-MAL is a phospholipid compound with thiol activity.
V74082 DSPE-N3 2839508-98-2 DSPE-N3 is a lipid.
V74079 DSPE-NHS 1383932-86-2 DSPE-NHS is a bioconjugated phospholipid molecule with two hydrophobic lipid tails.
V74072 DSPE-PEG Carboxylic acid sodium (MW 2000) 1403744-37-5 DSPE-PEG Carboxylic acid sodium (MW 2000) is a polyethylene glycol lipid that may be utilized to form micelles as nanoparticles for drug delivery.
V73429 DSPE-PEG-Amine (MW 10000) (ammonium) (DSPE-PEG-NH2 (MW 10000) (ammonium)) 474922-26-4 DSPE-PEG-Amine (MW 10000) (ammonium) is a phosphoethanolamine involved in the synthesis/preparation of liposomes for delivery systems.
V74057 DSPE-PEG-Amine (MW 2000) (ammonium) (DSPE-PEG-NH2 (MW 2000) (ammonium)) 474922-26-4 DSPE-PEG-Amine (MW 2000) (ammonium) is an amine analogue of the phospholipid polyethylene glycol used in the synthesis/preparation of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.
V77060 DSPE-PEG-Azide (MW 2000) DSPE-PEG-Azide (MW 2000) is a lipid-containing azide that may be utilized to form micelles as nanoparticles for drug delivery.
V80719 DSPE-PEG-DBCO (MW 2000) DSPE-PEG-DBCO (MW 2000) is a phospholipid PEG polymer that may be utilized to form micelles as lipid nanoparticles for drug delivery.
V77059 DSPE-PEG-Folate (MW 2000) DSPE-PEG-Folate (MW 2000) is a PEG analogue containing folate.
V74080 DSPE-PEG-Folate (MW 3350) 1236288-25-7 DSPE-PEG-Folate (MW 3350) is a PEG analogue containing folate.
V77058 DSPE-PEG-Folate (MW 5000) DSPE-PEG-Folate (MW 5000) is a PEG analogue containing folate.
V77057 DSPE-PEG-NHS (MW 3400) DSPE-PEG-NHS (MW 3400) is a PEG-modified phospholipid analogue that may be utilized to prepare liposomes for the delivery of DNA or mRNA vaccines.
V77056 DSPE-PEG-SH (MW 2000) DSPE-PEG-SH (MW 2000) is a polymer formed by the reaction of PEG-modified phospholipids and maleimide.
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