Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V73490 | 6-Bromohexyl 2-hexyldecanoate | 2644752-91-8 | 6-Bromohexyl 2-hexyldecanoate is a lipid. | |
V73467 | 7-Oxotridecanedioic acid | 101171-43-1 | 7-Oxotridecanedioic acid is a degradable cationic lipid intermediate compound used in the formation of lipid nanoparticles. | |
V73409 | 80-O14B | 1624618-01-4 | 80-O14B is a cationic lipid-like compound for CRISPR/Cas9 delivery. | |
V74083 | 93-O17S | 2227008-67-3 | 93-O17S is a cationic lipid used to prepare lipid nanoparticles (LNPs). | |
V73444 | A12-Iso5-4DC19 | 2412492-20-5 | A12-Iso5-4DC19 is an ionizable cationic lipid. | |
V60073 | A18-Iso5-2DC18 | 2412492-09-0 | A18-Iso5-2DC18 (compound A18) is a cyclic ionizable cationic lipid that promotes mRNA protein expression and induces strong mediated immune responses. | |
V73453 | A2-Iso5-4DC19 | 2412492-19-2 | A2-Iso5-4DC19 is a lipid compound. | |
V74073 | AA-T3A-C12 | 2938207-23-7 | AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). | |
V41502 | ALC-0159 | 1849616-42-7 | ALC-0159 (ALC0159; ALC 0159) is PEGylated lipid (PEG/lipid conjugate) and non-ionic surfactant usedin thePfizer-BioNTechSARS-CoV-2(COVID-19) mRNA vaccine containing the active ingredienttozinameran. | |
V2455 | ALC-0315 | 2036272-55-4 | ALC-0315 (ALC0315;ALC 0315) is a synthetic, colorless oily cationic lipid and an ionizable amino lipid used in combination with other lipids in the formation of lipid nanoparticles (LNPs) as non-viral gene delivery system. | |
V73434 | ALC-0315 analogue-1 | 2707440-55-7 | ALC-0315 analog-1 (compound P-10) is a cationic lipid. | |
V73418 | ALC-0315 analogue-2 | 2707439-64-1 | ALC-0315 analogue-2 is an analogue of ALC-0315. | |
V74049 | ApoA-I mimetic peptide | 221882-20-8 | ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) has good lecithin:cholesterol acyltransferase (LCAT) activating effect. | |
V74074 | ATX-002 | 1777792-34-3 | ATX-002 is an ionizable cationic lipid for RNA drug delivery. | |
V60071 | BAMEA-O16B | 2490668-30-7 | BAMEA-O16B is a lipid nanoparticles. | |
V73421 | BP Lipid 114 | 2714482-25-2 | BP Lipid 114 is an ethanolamine ionizable lipid (CN113387825A). | |
V73463 | BP Lipid 135 | 2089251-35-2 | BP Lipid 135 is a cationically ionizable lipid. | |
V74075 | C14-4 | 2639634-80-1 | C14-4 is an ionizable lipid used in the preparation /synthesis of lipid nanoparticles. | |
V77149 | Cholesterol (Water Soluble) | Cholesterol Water Soluble may be utilized to study the effects of cholesterol on potassium currents in inner hair cells. | ||
V73486 | CL4F8-6 | 2766493-12-1 | CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. |