Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.

Liposome related products

Structure Cat No. Product Name CAS No. Product Description
V73490 6-Bromohexyl 2-hexyldecanoate 2644752-91-8 6-Bromohexyl 2-hexyldecanoate is a lipid.
V73467 7-Oxotridecanedioic acid 101171-43-1 7-Oxotridecanedioic acid is a degradable cationic lipid intermediate compound used in the formation of lipid nanoparticles.
V73409 80-O14B 1624618-01-4 80-O14B is a cationic lipid-like compound for CRISPR/Cas9 delivery.
V74083 93-O17S 2227008-67-3 93-O17S is a cationic lipid used to prepare lipid nanoparticles (LNPs).
V73444 A12-Iso5-4DC19 2412492-20-5 A12-Iso5-4DC19 is an ionizable cationic lipid.
V60073 A18-Iso5-2DC18 2412492-09-0 A18-Iso5-2DC18 (compound A18) is a cyclic ionizable cationic lipid that promotes mRNA protein expression and induces strong mediated immune responses.
V73453 A2-Iso5-4DC19 2412492-19-2 A2-Iso5-4DC19 is a lipid compound.
V74073 AA-T3A-C12 2938207-23-7 AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid).
V41502 ALC-0159 1849616-42-7 ALC-0159 (ALC0159; ALC 0159) is PEGylated lipid (PEG/lipid conjugate) and non-ionic surfactant usedin thePfizer-BioNTechSARS-CoV-2(COVID-19) mRNA vaccine containing the active ingredienttozinameran.
V2455 ALC-0315 2036272-55-4 ALC-0315 (ALC0315;ALC 0315) is a synthetic, colorless oily cationic lipid and an ionizable amino lipid used in combination with other lipids in the formation of lipid nanoparticles (LNPs) as non-viral gene delivery system.
V73434 ALC-0315 analogue-1 2707440-55-7 ALC-0315 analog-1 (compound P-10) is a cationic lipid.
V73418 ALC-0315 analogue-2 2707439-64-1 ALC-0315 analogue-2 is an analogue of ALC-0315.
V74049 ApoA-I mimetic peptide 221882-20-8 ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) has good lecithin:cholesterol acyltransferase (LCAT) activating effect.
V74074 ATX-002 1777792-34-3 ATX-002 is an ionizable cationic lipid for RNA drug delivery.
V60071 BAMEA-O16B 2490668-30-7 BAMEA-O16B is a lipid nanoparticles.
V73421 BP Lipid 114 2714482-25-2 BP Lipid 114 is an ethanolamine ionizable lipid (CN113387825A).
V73463 BP Lipid 135 2089251-35-2 BP Lipid 135 is a cationically ionizable lipid.
V74075 C14-4 2639634-80-1 C14-4 is an ionizable lipid used in the preparation /synthesis of lipid nanoparticles.
V77149 Cholesterol (Water Soluble) Cholesterol Water Soluble may be utilized to study the effects of cholesterol on potassium currents in inner hair cells.
V73486 CL4F8-6 2766493-12-1 CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14.
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