Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.

Liposome related products

Structure Cat No. Product Name CAS No. Product Description
V50916 CRX-547 216014-05-0 lipid A mimetic
V82217 CTP-NBD 1268513-27-4 CTP-NBD is a cell-penetrating/penetrable and specific NFκB inhibitor.
V20104 D-Lin-MC3-DMA 1224606-06-7 D-Lin-MC3-DMA is a potent andionizable / cationic lipid that has been used for synthesis of lipid nanoparticles (LNPs, gene vector) to deliver siRNA.
V73410 DGDG 63142-69-8 DGDG, a chloroplast lipid, is a bilayer-forming lipid.
V73485 di-Pal-MTO 1349197-90-5 di-Pal-MTO is a palm oil-based lipid produced by combining the anti-cancer active molecule mitoxantrone (MTO) with palmitoleic acid.
V73437 Diamino lipid DAL4 2939000-43-6 Diamino lipid DAL4 is a new type of lipid nanoparticles (LNPs) that can encapsulate mRNA encoding cytokines such as IL-12, IL-27 and GM-CSF.
V82220 Dicamba-(CH2)5-acid 2892008-07-8 Hapten Dca is an immune hapten.
V73476 Dielaidoylphosphatidylethanolamine (DEPE) 16777-83-6 Dielaidoylphosphatidylethanolamine is a liposome used to deliver active molecules.
V74064 Dimethyldioctadecylammonium bromide (Dioctadecyldimethylammonium bromide; DODAB) 3700-67-2 Dimethyldioctadecylammonium bromide is a synthetic cationic lipid widely used in gene delivery and vaccine development.
V74066 DLin-K-C3-DMA 1217306-46-1 DLin-K-C3-DMA is a cationic lipid that may be utilized in the synthesis/preparation of nucleic acid lipid particles to deliver nucleic acids.
V20103 DLin-KC2-DMA 1190197-97-7 DLin-KC2-DMA is novel ionizable and cationic lipid useful for siRNA delivery.
V73439 DLin-M-C4-DMA 1226909-66-5 DLin-M-C4-DMA (Compound MC4) is a cationic lipid.
V20102 DLinDMA 871258-12-7 DLinDMA (1,2-dilinoleyloxy-3-dimethylaminopropane) is anionizable cationic lipid used for siRNA delivery.
V74056 DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) 18194-25-7 DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists.
V74051 DMG-PEG 2000 160743-62-4 DMG-PEG 2000 is used for the preparation of liposomes for siRNA transfection (siRNA delivery), which can improve the transfection efficiency.
V73411 DMPE (Dimyristoylphosphatidylethanolamine; 1,2-Ditetradecyl-rac-glycero-3-phosphoethanolamine) 20255-95-2 DMPE is dimyristoylphosphatidylcholine.
V73414 DMPG sodium 200880-40-6 DMPG sodium is a biochemical compound that could be utilized as a biomaterial or organic/chemical reagent for biomedical research.
V74054 DODAP 127512-29-2 DODAP is a cationic lipid.
V73468 DODAP hydrochloride 329009-00-9 DODAP (HCl) is an ionizable lipid.
V4874 DOPA-NA 108392-02-5 1,2-Dioleoyl-sn-glycero-3-phosphate sodium salt (18:1 PA) is an anionic lipid that may be utilized to prepare liposomes, micelles, and artificial membranes.
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