Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V50916 | CRX-547 | 216014-05-0 | lipid A mimetic | |
V82217 | CTP-NBD | 1268513-27-4 | CTP-NBD is a cell-penetrating/penetrable and specific NFκB inhibitor. | |
V20104 | D-Lin-MC3-DMA | 1224606-06-7 | D-Lin-MC3-DMA is a potent andionizable / cationic lipid that has been used for synthesis of lipid nanoparticles (LNPs, gene vector) to deliver siRNA. | |
V73410 | DGDG | 63142-69-8 | DGDG, a chloroplast lipid, is a bilayer-forming lipid. | |
V73485 | di-Pal-MTO | 1349197-90-5 | di-Pal-MTO is a palm oil-based lipid produced by combining the anti-cancer active molecule mitoxantrone (MTO) with palmitoleic acid. | |
V73437 | Diamino lipid DAL4 | 2939000-43-6 | Diamino lipid DAL4 is a new type of lipid nanoparticles (LNPs) that can encapsulate mRNA encoding cytokines such as IL-12, IL-27 and GM-CSF. | |
V82220 | Dicamba-(CH2)5-acid | 2892008-07-8 | Hapten Dca is an immune hapten. | |
V73476 | Dielaidoylphosphatidylethanolamine (DEPE) | 16777-83-6 | Dielaidoylphosphatidylethanolamine is a liposome used to deliver active molecules. | |
V74064 | Dimethyldioctadecylammonium bromide (Dioctadecyldimethylammonium bromide; DODAB) | 3700-67-2 | Dimethyldioctadecylammonium bromide is a synthetic cationic lipid widely used in gene delivery and vaccine development. | |
V74066 | DLin-K-C3-DMA | 1217306-46-1 | DLin-K-C3-DMA is a cationic lipid that may be utilized in the synthesis/preparation of nucleic acid lipid particles to deliver nucleic acids. | |
V20103 | DLin-KC2-DMA | 1190197-97-7 | DLin-KC2-DMA is novel ionizable and cationic lipid useful for siRNA delivery. | |
V73439 | DLin-M-C4-DMA | 1226909-66-5 | DLin-M-C4-DMA (Compound MC4) is a cationic lipid. | |
V20102 | DLinDMA | 871258-12-7 | DLinDMA (1,2-dilinoleyloxy-3-dimethylaminopropane) is anionizable cationic lipid used for siRNA delivery. | |
V74056 | DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) | 18194-25-7 | DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. | |
V74051 | DMG-PEG 2000 | 160743-62-4 | DMG-PEG 2000 is used for the preparation of liposomes for siRNA transfection (siRNA delivery), which can improve the transfection efficiency. | |
V73411 | DMPE (Dimyristoylphosphatidylethanolamine; 1,2-Ditetradecyl-rac-glycero-3-phosphoethanolamine) | 20255-95-2 | DMPE is dimyristoylphosphatidylcholine. | |
V73414 | DMPG sodium | 200880-40-6 | DMPG sodium is a biochemical compound that could be utilized as a biomaterial or organic/chemical reagent for biomedical research. | |
V74054 | DODAP | 127512-29-2 | DODAP is a cationic lipid. | |
V73468 | DODAP hydrochloride | 329009-00-9 | DODAP (HCl) is an ionizable lipid. | |
V4874 | DOPA-NA | 108392-02-5 | 1,2-Dioleoyl-sn-glycero-3-phosphate sodium salt (18:1 PA) is an anionic lipid that may be utilized to prepare liposomes, micelles, and artificial membranes. |