Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V74069 | N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide | 2922283-38-1 | N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analog of TT3. |
|
V74070 | NT1-014B | 2739805-64-0 | NT1-014B is a potent NT1-lipid encapsulating amphotericin B (AmB). |
|
V73456 | OF-Deg-Lin | 1853202-95-5 | OF-Deg-Lin is an ionizable aminolipid that may be utilized to prepare lipid nanoparticles. |
|
V73478 | PEG-bis-amine (MW 1000) (Poly(ethylene glycol)-bis-amine (MW 1000)) | 24991-53-5 | PEG-bis-amine (MW 1000) synthesizes folic acid-conjugated polymer micelles for encapsulation of the anticancer agent 9-nitrocamptothecin. |
|
V73416 | PEG-bis-amine (MW 8000) (Poly(ethylene glycol)-bis-amine (MW 8000)) | 24991-53-5 | PEG-bis-amine (MW 8000) synthesizes folic acid-conjugated polymer micelles for encapsulation of the anticancer agent 9-nitrocamptothecin. |
|
V76648 | PEG2000-C-DMG | PEG2000-C-DMG, a PEGylated lipid, may be utilized to prepare Onpattro. | |
|
V81065 | PEG2000-DGG | PEG2000-DGG is a synthetic lipid. | |
|
V74055 | PEG2000-DSPE | 247925-28-6 | PEG2000-DSPE may be utilized to prepare stable nucleic acid lipid particles (SNALPs). |
|
V73479 | Phospholipid PL1 | 2274812-94-9 | Phospholipid PL1 is a phospholipid-derived nanoparticle capable of delivering costimulatory receptor mRNA (CD137 or OX40) to T cells. |
|
V73449 | Piperazine-bis(ethyl octadeca-9,12-dienoate) | 2832061-33-1 | Piperazine-bis(ethyl octadeca-9,12-dienoate) is a cationic lipid that may be utilized to prepare lipid nanoparticles. |
|
V73464 | PPZ-A10 | 2941268-67-1 | PPZ-A10 is an ionizable cationic lipid that preferentially delivers mRNA to liver and spleen immune cells. |
|
V2598 | SM-102 | 2089251-47-6 | SM-102 (SM102) is a novel synthetic and ionizable amino lipid used for the delivery of mRNA-based vaccines. |
|
V73487 | Sorbitan tristearate | 26658-19-5 | Sorbitan tristearate is a non-ionic surfactant with synergistic effects on skin penetration. |
|
V60077 | ssPalmO-Phe | 2377474-67-2 | SSPalmO-Phe is an ionizable cationic lipid |
|
V73489 | Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate (304O13) | 1566559-80-5 | Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate is a biodegradable lipid prepared by the conjugate addition of alkylamines and acrylates. |
|
V73454 | VC1052 | 370108-98-8 | VC1052 is a component of Vaxfectin. |
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