Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.

Liposome related products

Structure Cat No. Product Name CAS No. Product Description
V77062 DSPE-PEG2000-Maleimide DSPE-PEG-Maleimide (MW 2000) is a PEG compound consisting of DSPE and maleimide groups.
V73472 DSPE-Pyrene 2933318-11-5 DSPE-Pyrene is a polycyclic aromatic hydrocarbon-containing phospholipid molecule that can be used for drug encapsulation, such as drug-loaded liposomes or nanoparticles.
V79219 DSPE-Rhodamine DSPE-Rhodamine is a Rhodamine B-labeled phospholipid DSPE.
V73483 DSPE-SPDP 144735-79-5 DSPE-SPDP is a phospholipid molecule.
V73448 DSPE-succinic acid 248253-94-3 DSPE-succinic acid is a phospholipid with a carboxylic acid terminal end.
V74081 DSPE-Thiol 144735-82-0 SPE-Thiol is a phospholipid with terminal thiol groups.
V74065 G0-C14 1510653-27-6 G0-C14 is a cationic lipid compound alkyl-modified polyaminoamine (PAMAM) dendrimer.
V73433 Gal-C4-Chol 219850-70-1 Gal-C4-Chol is a glycosylated cholesterol analogue.
V79572 Genevant CL1 monohydrochloride Genevant CL1 mono HCl is an ionizable cationic lipid (lipid 10, pKa=6.3) that can be used for mRNA lipid nanoparticle (LNP) vaccine delivery.
V76978 GL67 pentahydrochloride (N4-Spermine cholesteryl carbamate pentahydrochloride) GL67 (N4-Spermine cholesteryl carbamate) (penta HCl) is a cationic lipid.
V73419 Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate 2714482-26-3 Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate may be utilized in liposome delivery systems for the delivery of mRNA vaccines.
V74050 ionizable lipid-1 2055939-68-7 Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that may be utilized to prepare lipid nanoparticles (LNP) with a bilayer structure.
V80392 Ionizable lipid-1 hydrochloride Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that may be utilized to prepare lipid nanoparticles (LNP) with a bilayer structure.
V82218 Itaconic acid-13C5 (Itaconic acid 13C5) 2095777-38-9 Itaconic acid-13C5 is 13C (carbon 13) labelled Itaconic acid.
V60065 L319 1351586-50-9 L319 also known as O-8670, Lipid 319; RV-92, is an ionizable lipid.
V73420 Lipid 1 2226547-17-5 Lipid 1 is an ionizable aminolipid that may be utilized to prepare lipid nanoparticles.
V60072 Lipid 10 2430034-02-7 Lipid 10 is an ionizable aminolipid that may be utilized to prepare lipid nanoparticles.
V74076 Lipid 14 2430034-05-0 Lipid 14 is an ionizable aminolipid that may be utilized in the preparation /synthesis of lipid nanoparticles (LNPs).
V73455 Lipid 15 2588111-36-6 Lipid 15 is an ionizable aminolipid that may be utilized to prepare lipid nanoparticles.
V74067 Lipid 29 2244716-55-8 Lipid 29 is an ionizable aminolipid.
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