Reactive oxygen species (ROS) are radical and non-radical oxygen species produced by the partial reduction of oxygen, including superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•). Endogenous ROS are produced by cells during their normal oxidative metabolism in the mitochondria as well as when they react to xenobiotics, cytokines, and bacterial invasion.
By directly inhibiting MAPK phosphatases, ROS also activates MAPK pathways. Through PTEN, ROS produced by growth factor stimulation are capable of reversibly controlling the redox state of the PI3K pathway. The cellular response to ROS may involve the activation of autophagy.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V107140 | Xanthomicrol | 16545-23-6 | Xanthanol is extracted from the resin of Smilax glabra (Scrophulariaceae) and is an inhibitor of monoamine oxidases (MAOs). |
|
V72888 | XJB-5-131 | 866404-31-1 | XJB-5-131 is a ROS and electron scavenger targeting mitochondria. |
|
V98903 | α-Glucosylrutin | 130603-71-3 | α-Glucosylrutin is a potent antioxidant with free radical scavenging activity. |
|
V20405 | Efaproxiral (RSR13) | 131179-95-8 | Efaproxiral (RSR13)is a synthetic allosteric modifier of hemoglobin (Hb) andabezafibrate analogused forbrain metastases originating from breast cancer. |
|
V1969 | Efaproxiral Sodium (RSR13) | 170787-99-2 | Efaproxiral Sodium(RSR13) is a synthetic allosteric modifier of hemoglobin (Hb) and abezafibrate analog used for brain metastases originating from breast cancer. |
|
V2871 | Dihydroethidium | 104821-25-2 | Dihydroethidium (formerly known as Hydroethidine and PD-MY 003) is a cell-permeable blue fluorescent dye and a superoxide indicator which exhibits blue-fluorescence in the cytosol until oxidized, where it intercalates within the cell's DNA, staining its nucleus with a bright fluorescent red. |
|
V2768 | Dichloroacetate | 2156-56-1 | Dichloroacetate (CPC-211; DCA; X-11S) isa potent and specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively. |
|
V31055 | Procyanidin B2 | 29106-49-8 | Procyanidin B2 is a naturally occurring flavonoid with anti-tumor, antioxidant and other effects. |
|
V2422 | Norbergenin | 79595-97-4 | Norbergenin is an ortho-desmethyl analogue of bergenin with moderate anti-oxidant effect (IC50 for scavenging DPPH free radicals is 13 μM; scavenging superoxide anion is 32 μM). |
|
V2213 | Disufenton sodium (NXY-059) | 168021-79-2 | NXY-059 (also known as Cerovive, OKN007, Disufenton Sodium) is a disulfonyl derivative that has shown a significant differences in arterial Po2 and pH between the experimental groups before ischemia in BBB permeability study with Po2 value of 112.9±9.7mm Hg and pH value of 7.443±0.01. |
|
V31815 | Neohesperidin dihydrochalcone | 20702-77-6 | Neohesperidin dihydrochalcone (Neohesperidin DC; NHDC),an artificial sweetener and a synthetic glycoside chalcone, is added to various foods and beverages as a low caloric artificial sweetener. |
|
V29430 | Riboflavin Tetrabutyrate | 752-56-7 | Riboflavin Tetrabutyrate is a lipophilic analogue ofRiboflavin(vitamin B2), which is a vitamin B and an important nutrient that plays a key role in maintaining health in humans and other animals. |
|
V31834 | Calycosin-7-O-β-D-glucoside | 20633-67-4 | Calycosin-7-O-β-D-glucoside is an isoflavone extracted from Astragalus membranaceus. |
|
V7963 | Photochlor (HTTP) | 149402-51-7 | Photochlor (HTTP),a photodynamic therapy (PDT) agent, is a lipophilic, second-generation, chlorin-based photosensitizer. |
|
V31525 | trans-Trimethoxyresveratrol | 22255-22-7 | Trans-Trimethoxyresveratrol is an analogue of Resveratrol (RSV), and it may be a more potent anti-inflammatory, antiangiogenic and vascular-disrupting agent when compared with resveratrol. |
|
V5205 | Asiaticoside (Madecassol) | 16830-15-2 | Asiaticoside (Madecassol), a novel and naturally occuring trisaccaride triterpene isolated fromCentella asiaticaanda skin whiening agent found in Cetella, suppresses TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts; Asiaticoside shows antioxidant, anti-inflammatory, and anti-ulcer properties. |
|
V1873 | Coelenterazine | 55779-48-1 | Coelenterazine, a luciferin which is a light-emitting molecule, is a luminescent enzyme substrate that is used for monitoring reporter genes in BRET, ELISA and HTS techniques. |
|
V11459 | Apigetrin (Apigenin-7-O-β-D-glucopyranoside; Cosmosiin; Apigenin 7-glucoside) | 578-74-5 | Apigetrin (Apigenin-7-O-β-D-glucopyranoside; Cosmosiin; Apigenin 7-glucoside) is a naturally occuring flavanoid derived from dandelions and exhibits significant anti-proliferative and antioxidant activity, scavengers of ROS. |
|
V40609 | Camalexin | 135531-86-1 | Camalexin is a naturally occuring indole-based phytoalexin isolated from Camelina sativa and Arabidopsis (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. |
|
V30439 | Phillygenin | 487-39-8 | Phillygenin(Phillygenol,Phillygenol;Epipinoresinol methyl ether,Sylvatesmin,Forsythigenol) is a naturally occurringa bioactive intergradient isolated from Osmanthus fragrans, showing diverse bioactivities such as anti-inflammatory, anti-obesity and antipyretic activities. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
