5-HT receptors (Serotonin receptors) are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems.5-HT1, 5-HT2, 5-HT3, 5-HT4, 5-HT5, 5-HT6, and 5-HT7 are the types. Both excitatory and inhibitory neurotransmission is mediated by them. The neurotransmitter serotonin, which serves as their inherently ligand, stimulates the serotonin receptors. Numerous neurotransmitters and hormones are released in response to stimulation of the serotonin receptors. Numerous biological and neurological functions, including aggression, anxiety, appetite, cognition, learning, memory, mood, nausea, sleep, and thermoregulation, are influenced by serotonin receptors. Many antidepressants, antipsychotics, anorectics, antiemetics, gastroprokinetic agents, antimigraine agents, hallucinogens, and entactogens are among the pharmaceuticals that target the serotonin receptors.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V71174 | Zacopride hydrochloride | 101303-98-4 | Zacopride HCl is a highly efficient 5-HT3 receptor antagonist, with Kis values of 5-HT3 and 5-HT4 receptors of 0.38 and 373 nM respectively. |
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V70027 | Zimelidine dihydrochloride | 60525-15-7 | Zimelidine diHCl is a potent and specific inhibitor of serotonin 5-HT uptake and SERT. |
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V71202 | Ziprasidone amino acid (Ziprasidone Impurity C; Ziprasidone open ring impurity) | 1159977-64-6 | Ziprasidone amino acid (AA) (Ziprasidone Impurity C) is an impurity of Ziprasidone. |
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V21556 | Ziprasidone free base | 146939-27-7 | Ziprasidone (CP-88,059; CP 88059; CP-88,059-01; Geodon; Zeldox; Zipwell) is a dopamine and serotonin (5-HT) receptor antagonist with antipsychotic effects. |
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V0983 | Ziprasidone HCl (CP-88059) | 122883-93-6 | Ziprasidone (CP 88059; CP-88,059; CP-88,059-01; Geodon; Zeldox; Zipwell) HCl, the hydrochloride salt of Ziprasidone, is a novel and potent dopamine and serotonin (5-HT) receptor antagonist with antipsychotic effects. |
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V25710 | Ziprasidone HCl hydrate | 138982-67-9 | Ziprasidone HCl hydrate (CP88059) is a combined 5-HT (serotonin) and dopamine receptor antagonist that is licensed for the treatment of schizophrenia, has antipsychotic activity. |
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V0989 | Zolmitriptan | 139264-17-8 | Zolmitriptan (311C90; 311 C90; trade names AscoTop, Zomig, Zomigon, Zomigoro), an approved drug for the treatment of acute migraines, is a potent and highly selective 5-HT(1B/1D) receptor agonist of the triptan class. |
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V25760 | Zotepine | 26615-21-4 | Zotepine is a potent and 2nd generation antipsychotic with antidepressive and anxiolytic effects and can be used for the treatment for schizophrenia. |
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V71179 | α-Methylerotonin | 304-52-9 | α-Methylserotonin is a potent and specific agonist of 5-HT2 receptors. |
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