Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V80881 | N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine | N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a cytosine nucleoside analogue. | |
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V80548 | N6-Acetyloxymethyladenosine | N6-Acetyloxymethyladenosine is an adenine nucleoside analog. | |
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V80883 | N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine | N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine is an analogue of purine nucleoside. | |
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V80201 | N6-Ethyl-2'-beta-C-ethynyl adenosine | N6-Ethyl-2'-beta-C-ethynyl adenosine is an analogue of purine nucleoside. | |
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V80264 | N6-Ethyl-4'-thio-adenosine | N6-Ethyl-4'-thio-adenosine is an analogue of purine nucleoside. | |
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V80235 | N6-Methyl-2'-beta-C-ethynyl adenosine | N6-Methyl-2'-beta-C-ethynyl adenosine is an analogue of purine nucleoside. | |
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V80469 | N6-Methyl-2'-O-(2-methoxyethyl) adenosine | N6-Methyl-2'-O-(2-methoxyethyl) adenosine is an analogue of purine nucleoside. | |
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V80470 | N6-Methyl-3'-O-(2-methoxyethyl) adenosine | N6-Methyl-3'-O-(2-methoxyethyl) adenosine is an analogue of purine nucleoside. | |
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V80114 | N6-Pivaloyloxymethyladenosine | N6-Pivaloyloxymethyladenosine is an analogue of purine nucleoside. | |
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V80607 | N7-Methyl-2'-beta-C-methyl guanosine | N7-Methyl-2'-beta-C-methyl guanosine is an analogue of purine nucleoside. | |
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V80751 | N7-Methyl-2'-deoxy-2'-fluoroarabinoguanosine | N7-Methyl-2'-deoxy-2'-fluoroarabinoguanosine is an analogue of purine nucleoside. | |
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V80466 | N7-Methyl-2'-O-(2-methoxyethyl) guanosine | N7-Methyl-2'-O-(2-methoxyethyl) guanosine is an analogue of purine nucleoside. | |
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V77739 | Rev 2'-O-MOE-5MeC(Bz)-5'-amidite | Rev 2'-O-MOE-5MeC(Bz)-5'-amidite is an analogue of purine nucleoside. | |
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V81288 | Rev 2'-O-MOE-A(Bz)-5'-amidite | Rev 2'-O-MOE-A(Bz)-5'-amidite is an analogue of purine nucleoside. | |
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V77802 | Rev 2'-O-MOE-C(Bz)-5'-amidite | Rev 2'-O-MOE-C(Bz)-5'-amidite is an analogue of purine nucleoside. | |
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V81289 | Rev dC(Bz)-5'-amidite | Rev dC(Bz)-5'-amidite is an analogue of purine nucleoside. | |
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V7645 | RX-3117 | 865838-26-2 | RX-3117 (TV-1360; RX3117; fluorocyclopentenylcytosine), acytidine analog, is an orally bioavailable and potent DNA synthesis inhibitor with potential anticanceractivity. |
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V14006 | Sapacitabine (CS682; CYC682) | 151823-14-2 | Sapacitabine(CS-682; CYC-682) is a highly potent and orally bioactive pyrimidine analogue prodrug with potential anticancer activity. |
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V2188 | Triazavirin sodium hydrate (TZV, Riamilovir) | 928659-17-0 | :Triazavirin sodium hydrate (TZV, Riamilovir), a nucleoside analogue of nucleic acid, is a broad-spectrum and potent antiviral agent. |
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V77851 | Uridine-5-(N-Fmoc-methylamino)-acetyl (9-fluorenylmethyl) ester | Uridine-5-(N-Fmoc-methylamino)-acetyl (9-fluorenylmethyl) ester is an analogue of purine nucleoside. |
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