Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V80468 | N1-Methyl-3'-O-(2-methoxyethyl) adenosine | N1-Methyl-3'-O-(2-methoxyethyl) adenosine is an analogue of purine nucleoside. | |
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V80474 | N1-Methyl-3'-O-(2-methoxyethyl) inosine | N1-Methyl-3'-O-(2-methoxyethyl) inosine is an analogue of purine nucleoside. | |
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V81145 | N1-Methylpseudouridine-d3 (1-Methylpseudouridine-d3; N1-methyl-pseudouridine-d3) | N1-Methylpseudouridine-d3 is an analogue of purine nucleoside. | |
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V80873 | N1-Methylsulfonyl pseudouridine | N1-Methylsulfonyl pseudouridine is an analogue of purine nucleoside. | |
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V80687 | N1-Methylxylo-guanosine | N1-Methylxylo-guanosine is an analogue of purine nucleoside. | |
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V80463 | N3,5-Dimethyl-2'-O-(2-methoxyethyl) uridine | N3,5-Dimethyl-2'-O-(2-methoxyethyl) uridine is an analogue of purine nucleoside. | |
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V80602 | N3-(2-Methoxy)ethyluridine | N3-(2-Methoxy)ethyluridine is a uridine analog. | |
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V79315 | N3-(2S)-[2-(tert-Butoxycarbonyl)amino-3-(tert-butoxy carbonyl)]propyluridine | N3-(2S)-[2-(tert-Butoxycarbonyl)amino-3-(tert-butoxy carbonyl)]propyluridine is a uridine nucleoside analogue. | |
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V80874 | N3-(4-Nitrobenzyl)uridine | N3-(4-Nitrobenzyl)uridine is a uridine analog. | |
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V80556 | N3-(Butyn-3-yl)uridine | N3-(Butyn-3-yl)uridine is a uridine analog. | |
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V80875 | N3-[(Pyrid-4-yl)methyl]uridine | N3-[(Pyrid-4-yl)methyl]uridine is a uridine analog. | |
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V80045 | N3-[3-(tert-Butoxycarbonyl)amino]propyluridine | N3-[3-(tert-Butoxycarbonyl)amino]propyluridine is a uridine analog. | |
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V77431 | N3-Aminopseudouridine | N3-Aminopseudouridine is an analogue of purine nucleoside. | |
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V77936 | N3-Cyanoethyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine | N3-Cyanoethyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine is a uridine analog. | |
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V80276 | N4-(3,3,3-Trifluoropropanoyl)cytidine | N4-(3,3,3-Trifluoropropanoyl)cytidine is a cytosine nucleoside analog. | |
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V80878 | N4-(n-Palmitoyl)-4'-azido-2'-deoxy-2'-fluoro-arabinocytidine | N4-(n-Palmitoyl)-4'-azido-2'-deoxy-2'-fluoro-arabinocytidine is a cytosine nucleoside analogue. | |
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V77954 | N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-5-methyl-2'-deoxycytidine | N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-5-methyl-2'-deoxycytidine is an analogue of purine nucleoside. | |
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V80128 | N4-Benzoyl-2'-deoxy-2'-fluoro-β-D-arabinocytidine | N4-Benzoyl-2'-deoxy-2'-fluoro-β-D-arabinocytidine is an analogue of purine nucleoside. | |
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V80879 | N4-Benzoyl-2'-deoxy-5'-O-DMTr-2'-fluoro-5-methylcytidine | N4-Benzoyl-2'-deoxy-5'-O-DMTr-2'-fluoro- 5-methylcytidine is an analogue of purine nucleoside. | |
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V80880 | N4-Benzoyl-3'-O-(2-methoxyethyl)-5-methylcytidine | N4-Benzoyl-3'-O-(2-methoxyethyl)-5-methylcytidine is an analogue of purine nucleoside. |
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