Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V80234 | 6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine | 6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is an analogue of purine nucleoside. | |
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V81011 | 6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine | 6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is an analogue of purine nucleoside. | |
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V80949 | 6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine | 6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. | |
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V80979 | 6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine | 6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is an analogue of purine nucleoside. | |
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V80710 | 6-Amino-4-methoxy-1-(2-deoxy-aD-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine | 6-Amino-4-methoxy-1-(2-deoxy-aD-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. | |
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V80306 | 6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine | 6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is an analogue of purine nucleoside. | |
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V77673 | 6-Chloro-2-fluoropurine-9-bD-(3,5-bis-O-(p-toluoyl)-2-deoxy)riboside | 6-Chloro-2-fluoropurine-9-bD-(3,5-bis-O-(p-toluoyl)-2-deoxy)riboside is an analogue of purine nucleoside. | |
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V77674 | 6-Chloro-N1-(trimethylsilylethoxymethyl)pseudouridine | 6-Chloro-N1-(trimethylsilylethoxymethyl)pseudouridine is a uridine analog. | |
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V81054 | 6-Deoxo-8-oxo-3'-deoxy-guanosine | 2′-Deoxy-N-(2-furanylmethyl)guanosine is a guanine nucleoside analog. | |
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V80611 | 6-Methoxypurine-9-beta-D-(3-methoxy riboside) | 6-Methoxypurine-9-beta-D-(3-methoxy riboside) is an analogue of purine nucleoside. | |
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V80612 | 6-Methoxypurine-9-β-D-5'(R)-C-methylriboside | 6-Methoxypurine-9-β-D-5'(R)-C-methylriboside is a hypoxanthine analogue. | |
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V80238 | 6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine | 6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine is an analogue of purine nucleoside. | |
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V80613 | 6-O-Methyl-2'-O-methylinosine | 6-O-Methyl-2'-O-methylinosine is an analogue of purine nucleoside. | |
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V77793 | 6-S-(2-Cyanoethyl)-2'-deoxy-5'-O-DMTr--6-thioguanosine 3'-CED phosphoramidite | 6-S-(2-Cyanoethyl)-2'-deoxy-5'-O-DMTr--6-thioguanosine 3'-CED phosphoramidite is an analogue of purine nucleoside. | |
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V80478 | 7-(N-Acetylaminomethyl)-7-deazaguanosine | 7-(N-Acetylaminomethyl)-7-deazaguanosine is an analogue of purine nucleoside. | |
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V77313 | 7-Methyl-guanosine-5'-triphosphate sodium (m7GTP sodium) | 7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. | |
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V77690 | 8-(N,N-Dimethylaminomethyl)guanosine | 8-(N,N-Dimethylaminomethyl)guanosine is a guanine nucleoside analog. | |
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V77691 | 8-(N-Boc-aminomethyl)guanosine | 8-(N-Boc-aminomethyl)guanosine is a guanine nucleoside analog. | |
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V81012 | 8-Aza-2'-beta-C-methylguanosine | 8-Aza-2'-beta-C-methylguanosine is an analogue of purine nucleoside. | |
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V80482 | 8-Chloro-2'-deoxy-2'-fluoro inosine | 8-Chloro-2'-deoxy-2'-fluoro inosine is an analogue of purine nucleoside. |
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