| Size | Price | Stock | Qty |
|---|---|---|---|
| 25mg |
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| 50mg |
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| 100mg |
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| 250mg |
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| 500mg |
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| 1g |
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| Other Sizes |
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Purity: ≥98%
| Targets |
Nucleoside analogue; Influenza virus
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|---|---|
| ln Vitro |
Triazavirin's effectiveness against the tick-borne encephalitis virus is measured in a sensitive cell culture. Triazavirin is effective in inhibiting the reproduction of the tick-borne encephalitis virus (strain Sofiin) by accumulation in the SKEV cell culture at a concentration of 128 mcg/mL[2].
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| ln Vivo |
Triazavirin's effectiveness as a treatment against experimental Forest-Spring encephalitis in albino mice is investigated. The findings indicate that triazavirin, at high doses (200–400 mg/kg), protects the infected animals in a moderate way. Test groups' animal lifespans increased significantly (from 4.1 to 4.8 days) and there was a statistically significant drop in the amount of virus accumulation in the target organ[3].
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| References |
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| Molecular Formula |
C₅H₇N₆NAO₅S
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|---|---|
| Molecular Weight |
286.20
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| Exact Mass |
286.01
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| Elemental Analysis |
C, 20.98; H, 2.47; N, 29.37; Na, 8.03; O, 27.95; S, 11.20
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| CAS # |
928659-17-0
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| Related CAS # |
116061-59-7 (sodium);123606-06-4 (free);928659-17-0 (sodium hydrate);
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| Appearance |
Solid powder
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| SMILES |
CSC1=NN2C(=C(N=NC2=N1)[N+](=O)[O-])[O-].O.O.[Na+]
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| InChi Key |
GDVSBVWTWGUDAW-UHFFFAOYSA-M
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| InChi Code |
InChI=1S/C5H4N6O3S.Na.2H2O/c1-15-5-6-4-8-7-2(11(13)14)3(12)10(4)9-5;;;/h12H,1H3;;2*1H2/q;+1;;/p-1
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| Chemical Name |
sodium;7-methylsulfanyl-3-nitro-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-olate;dihydrate
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| Synonyms |
Triazavirin; Riamilovir; TZV; Riamilovir sodium hydrate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO: ~125 mg/mL (~436.8 mM)
H2O: ~50 mg/mL (~174.7 mM) |
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| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.4941 mL | 17.4703 mL | 34.9406 mL | |
| 5 mM | 0.6988 mL | 3.4941 mL | 6.9881 mL | |
| 10 mM | 0.3494 mL | 1.7470 mL | 3.4941 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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