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Nucleoside Antimetabolite(Analog)

Nucleoside Antimetabolite(Analog)

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite(Analog) related products

Structure Cat No. Product Name CAS No. Product Description
V3841 LY2334737 892128-60-8 LY2334737 is the orally bioavailable prodrug of gemcitabine that is cleaved systemically to gemcitabine,a nucleoside anticancer drug used in chemotherapy.
V80774 MicroRNA Agomir Negative Control MicroRNA Agomir negative control (NC) is a specially chemically modified miRNA mimic that can be used as a negative control (NC).
V78905 N,N-Dibenzoyl-2'-O-methyladdenosine N,N-Dibenzoyl-2'-O-methyladdenosine is an adenine nucleoside analog.
V80237 N1,N3-Bis(cyanomethyl)pseudouridine N1,N3-Bis(cyanomethyl)pseudouridine is an analogue of purine nucleoside.
V80870 N1-(1,1-Difluoroethyl)pseudouridine N1-(1,1-Difluoroethyl)pseudouridine is an analogue of purine nucleoside.
V80535 N1-(2-Methyl)propyl pseudouridine N1-(2-Methyl)propyl pseudouridine is an analogue of purine nucleoside.
V80266 N1-(N,N-Dimethylaminocarbonyl)-pseudouridine N1-(N,N-Dimethylaminocarbonyl)-pseudouridine is an analogue of purine nucleoside.
V77430 N1-Aminopseudouridine N1-Aminopseudouridine is an analogue of purine nucleoside.
V80270 N1-Benzoyl pseudouridine N1-Benzoyl pseudouridine is an analogue of purine nucleoside.
V80341 N1-Cyanomethyl pseudouridine N1-Cyanomethyl pseudouridine is an analogue of purine nucleoside.
V77749 N1-Ethyl-2'-O-TBDMS-5'-O-DMTr-3'-phosphoramidite N1-Ethyl-2'-O-TBDMS-5'-O-DMTr-3'-phosphoramidite is an analogue of purine nucleoside.
V80609 N1-Methyl-2'-beta-C-methyl adenosine N1-Methyl-2'-beta-C-methyl adenosine is an analogue of purine nucleoside.
V80606 N1-Methyl-2'-beta-C-methyl guanosine N1-Methyl-2'-beta-C-methyl guanosine is an analogue of purine nucleoside.
V80614 N1-Methyl-2'-beta-C-methyl inosine N1-Methyl-2'-beta-C-methyl inosine is an analogue of purine nucleoside.
V80753 N1-Methyl-2'-deoxy-2'-fluoroarabinoadenosine N1-Methyl-2'-deoxy-2'-fluoroarabinoadenosine is an analogue of purine nucleoside.
V80749 N1-Methyl-2'-deoxy-2'-fluoroarabinoguanosine N1-Methyl-2'-deoxy-2'-fluoroarabinoguanosine is an analogue of purine nucleoside.
V76728 N1-Methyl-2'-deoxyadenosine N1-Methyl-2'-deoxyadenosine, DNA adduct is an analogue of purine nucleoside.
V80467 N1-Methyl-2'-O-(2-methoxyethyl) adenosine N1-Methyl-2'-O-(2-methoxyethyl) adenosine is an analogue of purine nucleoside.
V80465 N1-Methyl-2'-O-(2-methoxyethyl) guanosine N1-Methyl-2'-O-(2-methoxyethyl) guanosine is an analogue of purine nucleoside.
V80473 N1-Methyl-2'-O-(2-methoxyethyl) inosine N1-Methyl-2'-O-(2-methoxyethyl) inosine is an analogue of purine nucleoside.
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