Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V81148 | 8-Chloro-2'-deoxy-2'-fluoro-arabino adenosine | 8-Chloro-2'-deoxy-2'-fluoro-arabino adenosine is an analogue of purine nucleoside. | |
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V81147 | 8-Chloro-2'-deoxy-2'-fluoroadenosine | 8-Chloro-2'-deoxy-2'-fluoroadenosine is an analogue of purine nucleoside. | |
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V80763 | 8-Chloro-2'-O-methyl inosine | 8-Chloro-2'-O-methyl inosine is an analogue of purine nucleoside. | |
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V77694 | 8-Hydroxy-3'-deoxy-3'-fluoroguanosine | 8-Hydroxy-3'-deoxy-3'-fluoroguanosine is an analogue of purine nucleoside. | |
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V81050 | 8-Hydroxy-3'-deoxyguanosine | 8-Hydroxy-3'-deoxyguanosine is an analogue of purine nucleoside. | |
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V79461 | 9-(2,3-Di-O-acetyl-6-O-benzoyl-5-deoxy-D-ribo-exofuranoyl)-6-chloropurine | 9-(2,3-Di-O-acetyl-6-O-benzoyl-5-deoxy-D-ribo-exofuranoyl)-6-chloropurine is an analogue of purine nucleoside. | |
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V77695 | 9-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-D-ribofuranosyl)-6-chloropurine | 9-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-D-ribofuranosyl)-6-chloropurine is an analogue of purine nucleoside. | |
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V80315 | Adenosine 2-amidine hydrochloride | Adenosine 2-amidine HCl is an adenine nucleoside analog. | |
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V77807 | Adenosine 5′-O-1-thiotriphosphate (disodium) | Adenosine 5′-O-(1-thiotriphosphate) (disodium) is an α-phosphate modified adenosine nucleotide. | |
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V3152 | Adenosine Dialdehyde (ADOX) | 34240-05-6 | Adenosine Dialdehyde (also named as ADOX), an adenosine analog, is an inhibitor of the S-adenosylmethionine-dependent methyltransferase with an IC50 of 40 nM. |
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V80269 | Adenosine-2-carboxy methyl amide | Adenosine-2-carboxy methyl amide is an analogue of purine nucleoside. | |
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V78429 | Biotin-16-dGTP tetralithium | Biotin-16-dGTP tetralithium is biotin-labeled dGTP that may be utilized to label oligonucleotides. | |
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V80275 | Confiden | Confiden is an analogue of purine nucleoside. | |
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V78853 | Confident | Confident is an analogue of purine nucleoside. | |
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V78854 | Confidential | Confidential is an analogue of purine nucleoside. | |
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V79823 | Confidential-2 | Confidential-2 is an analogue of purine nucleoside. | |
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V79038 | ddUTP (lithium), 100mM in H2O (2',3'-Dideoxyuridine-5'-triphosphate lithium) | ddUTP (lithium), 100mM in H2O is a nucleotide analog that can be incorporated into DNA, RNA, or other nucleic acids. | |
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V79148 | Di-O-Toluoyl-1,2-dideoxy-D-ribose-6-chloro-7-iodo-7-deazapurine | Di-O-Toluoyl-1,2-dideoxy-D-ribose-6-chloro-7-iodo-7-deazapurine is an analogue of purine nucleoside. | |
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V5320 | Elacytarabine | 188181-42-2 | Elacytarabine (also known as CP 4055; CP-4055),an antineoplastic drug, is a lipid-conjugated (5-elaidic acid ester) derivative and a prodrug of the nucleoside analog cytarabine (arabinoside; Ara-C). |
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V4887 | Gemcitabine elaidate | 210829-30-4 | Gemcitabine elaidate (formerly know as CP4126; CO101; CP-4126; CO-101) is a potent, lipophilic, unsaturated fatty acid ester derivative and prodrug form of gemcitabine (dFdC), which is an antimetabolite deoxynucleoside analogue with potential antitumor activity. |
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