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    GDC-0339
    GDC-0339

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    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V4527
    CAS #: 1428569-85-0Purity ≥98%

    Description: GDC-0339 is a novel,orally bioavailable, potent and selective small molecule pan-Pim kinase inhibitor with IC50 of 43.6 nM for BaF3 PIM1. GDC-0339 was discovered as a potential treatment of multiple myeloma.  

    References 2017 Oct;45(10):1084-1092.


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    GDC-0339

    Name: GDC-0339
    CAS#: 1428569-85-0
    Chemical Formula: C20H22F3N7OS
    Exact Mass: 465.1559
    Molecular Weight: 465.49
    Elemental Analysis: C, 51.60; H, 4.76; F, 12.24; N, 21.06; O, 3.44; S, 6.89
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Technical InformationSynonym: GDC-0339; GDC 0339; GDC0339
    IUPAC/Chemical Name: 5-Amino-N-(5-((4R,5R)-4-amino-5-fluoroazepan-1-yl)-1-methyl-1H-pyrazol-4-yl)-2-(2,6-difluorophenyl)thiazole-4-carboxamide
    InChi Key: NHXVGMQFCYBLTL-ZWNOBZJWSA-N
    InChi Code: InChI=1S/C20H22F3N7OS/c1-29-20(30-7-5-10(21)13(24)6-8-30)14(9-26-29)27-18(31)16-17(25)32-19(28-16)15-11(22)3-2-4-12(15)23/h2-4,9-10,13H,5-8,24-25H2,1H3,(H,27,31)/t10-,13-/m1/s1
    SMILES Code: O=C(C1=C(N)SC(C2=C(F)C=CC=C2F)=N1)NC3=C(N4CC[[email protected]@H](N)[[email protected]](F)CC4)N(C)N=C3


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