| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V4376 | RITUXIMAB | 174722-31-7; | Rituximab (trade name: Rituxan; Anti-Human CD20 type I, Chimeric Antibody) is an anti-CD20 chimeric monoclonal antibody (mAb) used to treat certain autoimmune diseases and types of cancer such as B-cell malignancies as well as organ transplantation. |
|
V3662 | RO-7 | 1370241-45-4 | RO-7 is a novel, potent and next-generation PA (polymerase) endonuclease inhibitor of influenza A and B viruses, but its drug resistance potential is unknown. |
|
V3653 | RO4938581 | 883093-10-5 | RO 4938581 (also known as Ro 4882224) is a novel, potent and selectiveGABAAα5inverse agonist, with aKiof 4.6 nM forGABAAα5β3γ2a, and shows a lower affinity at α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki, 174, 185, 80 nM, respectively); RO 4938581 is used in the research of cognitive dysfunction. |
|
V3124 | Ruboxistaurin (LY333531) mesylate | 192050-59-2 | Ruboxistaurin mesylate (LY333531mesylate), themesylate salt ofRuboxistaurin, is a potent and specific inhibitor of PKCβ (protein kinase C) with antidiabetic activity. |
|
V3810 | RV521 | 1903763-82-5 | RV521 is an orally bioactive, highly potent small-molecule inhibitor of RSV (respiratory syncytial virus)fusionprotein. |
|
V3811 | RV521 HCl | 1903763-83-6 | RV521 Hcl is an orally bioactive, highly potent small-molecule inhibitor of RSV (respiratory syncytial virus)fusionprotein. |
|
V2140 | Sabizabulin (VERU-111) | 1332881-26-1 | Sabizabulin (VERU-111; ABI-231) is a novel and orally bioavailable tubulin inhibitor that has the potential to treat cancer. |
|
V3249 | SB366791 analog | SB-366791 analog is a novel, potent, competitive and selective cinnamide antagonist of the vanilloid receptor (VR1/TRPV1). | |
|
V0763 | SCD1 Inhibitor | 1231243-91-6 | SCD1 Inhibitor is a novel,highly potent stearoyl-CoA desaturase1 (SCD1) inhibitor with thepotentialto be used for treatingvarious diseases such as obesity, cancer, diabetesandacne. |
|
V4233 | SCY-635 | 210759-10-7 | SCY-635 is a novel and potent nonimmunosuppressive cyclosporine-based analog that exhibits potent suppression of hepatitis C virus (HCV) replicationin vitro. |
|
V4397 | SERLOPITANT | 860642-69-9 | Serlopitant (also known as VPD-737 and MK-0594) is a novel, potent and selectiveantagonist of Neurokinin-1 (NK-1)receptor which is being evuluated in clinical trials for the treatment of urinary incontinence and overactive bladder, while it was superior to placebo it provided no advantage over existing drugs, and the further development was discontinued. |
|
V2689 | SGE516 | SGE-516, a synthetic neuroactive steroid, is a potent positive allosteric modulator of both synaptic and extrasynaptic GABAA receptors. | |
|
V2157 | SGX-523 | 1072116-01-8 | SGX-523 is a novel potent and ATP-competitive Met inhibitor with anticancer activity. |
|
V1272 | SH5-07 | 1456632-41-9 | SH5-07 (SH5 07; SH-507; SH5-07),a structural analogof BP-1-102, is a novel, potent and hydroxamic acid-based STAT3 inhibitor with potential antitumor activity. |
|
V3652 | SHIP2-IN-1 | 2252247-80-4 | SHIP2-IN-1 is a novel and potentSHIP2inhibitor which inhibits SHIP2 activity with anIC50of 2 µM. |
|
V3610 | Sofosbuvir D6 | Sofosbuvir D6 is the deuterated form and less active impurity ofSofosbuvir. | |
|
V3736 | SR-3737 | 1164153-37-0 | SR-3737, anamino pyrazole and indazole analog, is a potent JNK inhibitor but is non-selective for JNK3 (IC50 = 12 nM) and p38 (IC50 = 3 nM). |
|
V2158 | Takeda-6d | 1125632-93-0 | Takeda-6d is a novel dual inhibitor of DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) with anticancer activity. |
|
V3945 | Taminadenant HCl hydrate (PBF-509; NIR-178) | 2253894-78-7 | Taminadenant HCl (PBF509; NIR178) isa novel potent and oral non-xhantine non-furan A2AR (adenosine) antagonist with thepotential to be used as a pro-dopaminergic drug for PD management. |
|
V2159 | TASP0415914 | 1292300-75-4 | TASP0415914 is an orally potent phosphoinositide 3-kinase γ (PI3Kγ) inhibitor for the treatment of inflammatory diseases. |
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