Others 8

Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD
GPCR & G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase Adrenergic Receptor Angiotensin Receptor APJ Bombesin Receptor Bradykinin Receptor cAMP Cannabinoid Receptor CaSR CCK receptor CCR CGRP Receptor CRFR CXCR Dopamine Receptor EBI2 Endothelin Receptor Formyl Peptide Receptor Free Fatty Acid Receptor G protein-coupled Bile Acid Receptor GCGR GHSR GLP Receptor Glucagon Receptor GnRH Receptor GPCR19 GPR GPR109A Guanylate Cyclase Hedgehog(Smoothened) ROCK Histamine Receptor ICMT Leukotriene Receptor LPA Receptor LPL Receptor LTR mAChR Melanocortin Receptor Melatonin Receptor mGluR Motilin Receptor MRGPR MT Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor NPY receptor Opioid Receptor OX Receptor Oxytocin Receptor P2Y Receptor PAFR PAR PKD PKG Prostaglandin Receptor Ras RGS Protein S1P Receptor SGLT Sigma Receptor Somatostatin Receptor TAAR TSH Receptor Urotensin Receptor Vasopressin Receptor

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Others 8

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V3471	BMS-066	914946-88-6	BMS-066 is a novel and potent tricyclic pseudokinase inhibitors of IKKβ/Tyk2withIC50sof 9 nM and 72 nM, respectively.
V3516	BMS-346567	953807-31-3	BMS-346567, an analog of Sparsentan, is a novel, potent and selective dual angiotensin II and endothelin A receptor antagonist.
V2070	BMS-37	1675202-20-6	BMS-37 is a novel and potent small molecule inhibitor of the PD-1/PD-L1 protein protein interaction with IC50 value in the range of 6-100 nM in cell free assays.
V2110	BMS-751324	948842-66-8	BMS-751324 is a novel prodrug of BMS-582949 (also known as PS540446) which is a potent and highly selective p38 mitogen-activated protein kinase (p38 MAPK) inhibitor with IC50 of 13nM and is currently in phase II clinical trials for the treatment of rheumatoid arthritis.
V3468	BMS-819881	1197420-05-5	BMS-819881 is a novel and potent antagonist of MCHR1 (Melanin concentrating hormone receptor 1) with minimal hERG activity.
V3469	BMS-830216	1197420-06-6	BMS-830216 isa prodrug of BMS-819881 which is a novel and potent antagonist of MCHR1 (Melanin concentrating hormone receptor 1) with minimal hERG activity.
V3464	BMS-986163	1801151-09-6	BMS-986163, a novel water-soluble phosphate prodrug ofBMS-986169designed for IV administration, is a negative allosteric modulator ofGluN2B which is aN-methyl-d-aspartate receptor subtype.
V3465	BMS-986169	1801151-08-5	BMS-986169 is a novel and potent negative allosteric modulator ofGluN2B which is aN-methyl-d-aspartate receptor subtype.
V3498	BPN14770	1606975-12-5	BPN14770 is a novel and potent allosteric modulator of phosphodiesterase-4 (PDE4) with IC50 values of 8 and 130 nM for human and mouse PDE4D, respectively.
V3946	CA-327		CA-327 is a novel potent, orally available, small molecule and dual inhibitor of TIM3 and PD-L1 with potential anticancer activities.
V3631	Calyculin A	101932-71-2	Calyculin A is a novel, potent, selective and cell-permeable inhibitor of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) withIC50s of 0.5 to 1 nM.
V3889	Cannabidiol	13956-29-1	NOT AVAILABLE (CONTROLLED SUBSTANCE; Schedule I drugs under the Controlled Substances Act.
V3473	Cariprazine sulfate		Cariprazine (formerly known as MP-214 and RGH-188) is a novel and potent antipsychotic drug candidate that is in late-stage clinical development for the treatment of schizophrenia, as well as for bipolar disorder (manic/mixed and depressive episodes), and as an adjunctive agent for the treatment of major depressive disorder.
V4372	CETUXIMAB	205923-56-4	Cetuximab (C225; C 225; C-225; Erbitux) is a potent and specific chimeric monoclonal antibody approved for cancer treatment.
V3571	dBRD9	2170679-45-3	dBRD9 (dBRD-9) is a novel and potent PROTAC degrader of the BRD9 bromodomain and the cereblon E3 ubiquitin ligase complex with anticancer activity.
V2161	Desciclovir	84408-37-7	Desciclovir is a precursor of acyclovir (ACV), a potent and orally bioactive antiherpetic molecule.
V4390	DFMTI	864864-86-8	DFMTI is a novel compound that can completely block the rmGlu1 L757V glutamate response by acting as anovel mGlu₁ negative allosteric modulator.
V3960	DIETHYL PYIMDC	1821370-64-2	Diethyl pyimDC is a novel inhibitor of human CP4H1 (collagen prolyl 4-hydroxylase 1).
V2612	Diethylmaleate	141-05-9	Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NFkB.
V3228	DORA-22	1088991-95-0	DORA-22 is a novel, potent and selective dual orexin receptor antagonist that may be useful for insomnia andAD-relevant symptoms.