The acquired immunodeficiency syndrome (AIDS), a condition in which the immune system gradually fails and life-threatening opportunistic infections and cancers proliferate, is brought on by the lentivirus (a subgroup of retrovirus) known as HIV. HIV infection happens when blood, semen, vaginal fluid, pre-ejaculate, or breast milk are shared. HIV can be found in these bodily fluids as both free virus particles and as a virus inside infected immune cells.Important immune system components like helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells are all infected by HIV. Apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells are some of the mechanisms by which HIV infection results in low levels of CD4+ T cells. Cell-mediated immunity is lost and the body becomes progressively more vulnerable to opportunistic infections when CD4+ T cell counts fall below a critical threshold.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V54292 | Rhuscholide A | 944804-58-4 | Rhuscholide A is a benzofuran lactone with significant anti-HIV (Human Immunodeficiency Virus)-1 activity with EC50 of 1.62 μM. |
|
V13839 | RN-18 | 431980-38-0 | RN-18 is an HIV-1 Vif inhibitor. |
|
V8379 | Ro 24-7429 | 139339-45-0 | Ro 24-7429 (Ro247429; Ro-247429) is a novel and potent Tat (HIV-1 transactivator protein) antagonistwithanti-HIV, antifibrotic and anti-inflammatory activities. |
|
V54262 | Salvianan A | 2162956-63-8 | 1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) is a potent anti-HIV (Human Immunodeficiency Virus)-1 agent. |
|
V14330 | Saquinavir mesylate (Ro 31-8959; Invirase; Fortovase) | 149845-06-7 | Saquinavir mesylate(Ro-31-8959; Invirase; Fortovase),an HIV Protease Inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS. |
|
V80434 | Seletracetam lithium (Ucb 44212 lithium) | Seletracetam (Ucb 44212) lithium is an analogue of the antiepileptic drug Levetiracetam. | |
|
V54277 | Semzuvolimab (UB421) | 2409099-32-5 | Semzuvolimab is a murine IgG1κ antibody targeting the T cell surface antigen T4/Leu-3, p55 (CD4). |
|
V36624 | Siamycin I (BMY-29304) | 164802-68-0 | Siamycin I (BMY-29304) is a 21-residue tricyclic peptide that is a secondary metabolite (SM, chemical compound) of actinomycetes. |
|
V35243 | Suvizumab (KD-247) | 914257-21-9 | Suvizumab (KD-247) is a neutralizing antibody against HIV-1. |
|
V76176 | TAT (47-57) GGG-Cys(Npys) | 1231898-26-2 | TAT (47-57) GGG-Cys(Npys) is a cell-penetrable peptide (CPP). |
|
V76172 | TAT (47-57), FAM-labeled | 1676104-81-6 | TAT (47-57), FAM-labeled is a cell-penetrable peptide (CPP). |
|
V81516 | TAT (48-57) (TFA) | TAT (48-57) (TFA) is a cell membrane-permeable (penetrable) polypeptide extracted from amino acid (AA) residues 48-57 of the HIV-1 transactivator (Tat) transcription protein. | |
|
V76454 | TAT peptide | TAT peptide is a cell-penetrating/penetrable peptide (GRKKRRQRRRPQ) developed from HIV-1 reverse transcription activator (Tat). | |
|
V76453 | TAT peptide TFA | TAT peptide (TFA) is a cell-penetrating/penetrable peptide (GRKKRRQRRRPQ) developed from HIV-1 reverse transcription activator (Tat). | |
|
V81523 | TAT-GluR23A Fusion Peptide | TAT-GluR23A Fusion Peptide is a biologically active peptide. | |
|
V81530 | TAT-NSF700scr | TAT-NSF700scr contains the complete TAT domain and glycine linker, followed by randomly arranged NSF amino acid (AA)s. | |
|
V81546 | TC14012 TFA | TC14012 TFA is a serum-stable analogue of T140 and a selective CXCR4 antagonist (inhibitor) with IC50 of 19.3 nM. | |
|
V3503 | Temsavir | 701213-36-7 | Temsavir (formerly known as BMS626529; BMS-626529) is a novel, potent attachment inhibitor that targetsHIV-1gp120 and prevents its binding to CD4+T cells. |
|
V53235 | Tenofovir diphosphate disodium (TFV-DP disodium) | 2738719-07-6 | Tenofovir diphosphate disodium is an antiviral reverse transcription agent and inhibitor of DNA polymerase. |
|
V16066 | Tenofovir exalidex (CMX-157) | 911208-73-6 | Tenofovir exalidex (formerly known as HDP-Tenofovir and CMX-157) is a novel and potent lipophilic / acyclic nucleoside phosphonate that is able to deliver high concentrations of the active antiviral agent tenofovir to target cells. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
