The acquired immunodeficiency syndrome (AIDS), a condition in which the immune system gradually fails and life-threatening opportunistic infections and cancers proliferate, is brought on by the lentivirus (a subgroup of retrovirus) known as HIV. HIV infection happens when blood, semen, vaginal fluid, pre-ejaculate, or breast milk are shared. HIV can be found in these bodily fluids as both free virus particles and as a virus inside infected immune cells.Important immune system components like helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells are all infected by HIV. Apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells are some of the mechanisms by which HIV infection results in low levels of CD4+ T cells. Cell-mediated immunity is lost and the body becomes progressively more vulnerable to opportunistic infections when CD4+ T cell counts fall below a critical threshold.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V54242 | Fipravirimat (GSK3640254) | 1818867-24-1 | Fipravirimat is a potent HIV-1 inhibitor. |
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V53385 | Fipravirimat dihydrochloride (GSK3640254 dihydrochloride) | 2442512-14-1 | Fipravirimat diHCl is a potent HIV-1 inhibitor. |
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V79430 | FITC-LC-TAT (47-57) | FITC-LC-TAT (47-57) is a FITC-labeled TAT peptide. | |
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V79432 | FITC-Trecovirsen sodium (FITC-GEM91 sodium) | FITC-Trecovirsen (sodium) is a FITC-labeled version of Trecovirsen. | |
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V4948 | Fosamprenavir | 226700-79-4 | Fosamprenavir (also known as GW433908; Amprenavir phosphate; GW-433908) is a phosphate ester prodrug of Amprenavir with improved solubility and antiviral effects. |
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V52086 | Fosdevirine (GSK2248761; FDV) | 1018450-26-4 | Fosdevirine (GSK2248761) is a specific, non-nucleoside reverse transcriptase inhibitor (NNRTI) that can inhibit human immunodeficiency virus type 1 (HIV-1) replication with low sodium in vitro Molar activity. |
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V3501 | Fostemsavir (BMS663068) | 864953-29-7 | Fostemsavir (BMS-663068; BMS663068;Rukobia), the phosphonooxymethyl prodrug of BMS-626529, is an approved (in 2020) antiretroviral medication for adults living with HIV/AIDS. |
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V29032 | Fostemsavir Tris (BMS-663068 trisaminomethane) | 864953-39-9 | Fostemsavir Tris (BMS-663068trisaminomethane or tromethamine or THAM) is thetrisaminomethane salt ofFostemsavir (BMS663068; BMS-663068;Rukobia) which is an anti-HIV medication marketed in 2020. |
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V9288 | Gardiquimod DiTFA salt | 1020412-43-4 | GardiquimodDiTFA salt is a specificTLR7 agonist with anticancer and anti-HIV-1 activities. |
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V54259 | Glycolithocholic acid 3-sulfate disodium (Glycolithocholate sulfate disodium; Sulfolithocholylglycine disodium; SLCG disodium) | 64936-82-9 | Glycolithocholic acid 3-sulfate (disodium) inhibits HIV-1 replication. |
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V52049 | Gomisin M1 ((±)-Gomisin M1) | 82467-50-3 | Gomisin M1 ((±)-Gomisin M1) is a potent anti-HIV (Human Immunodeficiency Virus) agent with EC50 of <0.65 μM. |
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V54285 | Gomisin M2 ((+)-Gomisin M2) | 82425-45-4 | Gomisin M2 ((+)-Gomisin M2) is a lignan extracted from the fruit of Schisandra rubriflora and has anti-HIV activity (EC50 of 2.4 μM). |
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V79639 | GP120, HIV-1MN | GP120, HIV-1 MN is a bioactive peptide. | |
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V54279 | GPS491 | 2655502-29-5 | GPS491 (EC50 = 0.47 μM) inhibits the expression of HIV-1 structural protein Gag and changes the accumulation of HIV-1 RNA, reducing the abundance of RNA encoding structural proteins while increasing the levels of viral RNA encoding regulatory proteins. |
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V54278 | GS-9822 | 2219362-41-9 | GS-9822 is a potent antiviral compound against wild-type HIV-1 virus with nanomolar activity. |
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V76313 | GSK2838232 | 1443460-91-0 | GSK2838232 inhibits HIV reverse transcriptase activity. |
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V52012 | HBV Seq2 aa:179-186 | 337464-42-3 | HBV (hepatitis B virus) Seq2 aa:179-186 serves as an efficient motif for CTL responses in the H-2b system after restimulation of primed T cells in vitro. |
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V76178 | HEP-1 (Human ezrin peptide (324-337)) | 174641-44-2 | HEP-1 (Human ezrin peptide (324-337)) is an orally administered peptide with anti-HIV activity. |
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V51988 | HIV-1 capsid inhibitor 1 | 2396382-78-6 | HIV-1 capsid inhibitor 1 is a potent HIV-1 Capsid inhibitor (antagonist) with EC50 of 3.13 µM. |
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V57504 | HIV-1 gag Protein p24 (194-210) | 141281-67-6 | HIV-1 gag Protein p24 (194-210) is a bioactive peptide discovered by peptide screening. |
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