The acquired immunodeficiency syndrome (AIDS), a condition in which the immune system gradually fails and life-threatening opportunistic infections and cancers proliferate, is brought on by the lentivirus (a subgroup of retrovirus) known as HIV. HIV infection happens when blood, semen, vaginal fluid, pre-ejaculate, or breast milk are shared. HIV can be found in these bodily fluids as both free virus particles and as a virus inside infected immune cells.Important immune system components like helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells are all infected by HIV. Apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells are some of the mechanisms by which HIV infection results in low levels of CD4+ T cells. Cell-mediated immunity is lost and the body becomes progressively more vulnerable to opportunistic infections when CD4+ T cell counts fall below a critical threshold.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V76175 | Murabutide | 74817-61-1 | Murabutide is a safe synthetic immune modulator. |
|
V41143 | Myriceric acid B (Myriceric acid B) | 55497-79-5 | Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41. |
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V26355 | Nelfinavir (AG-1341) | 159989-64-7 | Nelfinavir (formerly AG-1341) is a novel, potent and orally bioavailable HIV-1 protease inhibitor/PI with a Kiof 2 nM. |
|
V54265 | Neotripterifordin | 149249-32-1 | Neotripterifordin is an HIV inhibitor. |
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V52595 | Nevirapine-d3 (Nevirapine d3) | 1051419-24-9 | Nevirapine-d3 is the deuterated form of Nevirapine. |
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V54291 | Nevirapine-d4 (nevirapine d4) | 1051418-95-1 | Nevirapine-d4 is the deuterated form of Nevirapine. |
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V41101 | NNRTIs-IN-1 | 2925364-09-4 | NNRTIs-IN-1 is a potent non-nucleoside reverse transcriptase inhibitor (antagonist) with significant resistance against drug resistance. |
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V81039 | PAP 248–286 (Prostatic Acid Phosphatase(248-286)) | PAP 248–286 is a biologically active peptide. | |
|
V76167 | Pentosan Polysulfate | 37300-21-3 | Pentosan Polysulfate is an orally bioavailable, semi-synthetic active molecule with anti-inflammatory and pro-chondrogenic properties. |
|
V76312 | Pentosan Polysulfate Sodium (W/W 43%) | 140207-93-8 | Pentosan Polysulfate Sodium is an orally bioavailable, semi-synthetic active molecule with anti-inflammatory and pro-chondrogenic properties. |
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V54213 | Periglaucine A | 1025023-04-4 | Periglaucine A is a hasubanane-type alkaloid extracted from Pericampylus glaucus. |
|
V54250 | Peritassine A | 262601-67-2 | Peritassine A is an alkaloid extracted from Tripterygium wilfordii Hook. |
|
V3323 | PF-3450074 | 1352879-65-2 | PF-3450074 (also known as PF74) is a HIV-1 capsid-targeting small molecule antiviral compound which directly binds to the capsid (CA) protein at a site also utilized by host cell proteins CPSF6 and NUP153. |
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V40998 | Pirmitegravir (STP0404) | 2245231-10-9 | Pirmitegravir is a potent, first-in-class allosteric integrase (ALLINI) inhibitor that targets the LEDGF/p75 binding site. |
|
V53411 | PMEDAP | 113852-41-8 | PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication. |
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V61141 | Pol (476-484), HIV-1 RT Epitope | 139079-41-7 | Pol (476-484), HIV-1 RT Epitope is a biologically active peptide. |
|
V54244 | PYR01 | 2560576-15-8 | PYR01 is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor. |
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V52957 | Reverse transcriptase-IN-1 | 2380001-43-2 | Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally bioactive HIV-1 non-nucleoside reverse transcriptase inhibitor. |
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V78489 | Reverse transcriptase-IN-3 | Reverse transcriptase-IN-3 is a pyrimidine-5-carboxamide analogue and an inhibitor (blocker/antagonist) of HIV-1. | |
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V80182 | Reverse transcriptase-IN-4 | Reverse transcriptase-IN-4 (compound F10) is a potent and specific non-nucleoside reverse transcriptase (NNRT) inhibitor (antagonist) with EC50 of 0.053 μM against wild-type HIV-1 and against HIV-1 mutant strains. |
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