Hepatitis B virus, also known as HBV or Orthohepadnavirus, is a type of virus that belongs to the Hepadnaviridae family of viruses. Hepatitis B is brought on by the virus HBV. The ground squirrel hepatitis virus, the woodchuck hepatitis virus, and the woolly monkey hepatitis B virus are the other three species that make up the Orthohepadnavirus, of which the hepatitis B virus is the type species. The Hepadnaviridae family includes the genus as a member. Based on antigenic epitopes found on its envelope proteins, HBV is classified into four major serotypes (adr, adw, ayr, ayw), and eight genotypes (A-H) based on the genome's overall nucleotide sequence variation.The genotypes are used to track the evolution and spread of the virus because they have a distinct geographic distribution. The severity of the disease, the progression and propensity for complications, the response to treatment, and perhaps vaccination, are all impacted by genotype differences.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V5190 | Morphothiadin (GLS4) | 1092970-12-1 | Morphothiadin (formerly GLS-4; GLS4) is a novel, potent and selective inhibitor of HBV replication, effective against both wild-type and adefovir-resistant HBV with an IC50of 12 nM. |
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V54180 | Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) | 123410-65-1 | Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) is an HBV (hepatitis B virus) inhibitor. |
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V54187 | Neracorvir | 2243162-66-3 | Neracorvir is a potent antiviral compound. |
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V25189 | NVR 3-778 | 1445790-55-5 | NVR 3-778 is a first-in-class, potent and oral bioavailable capsid assembly modulator against the hepatitis B virus [HBV CAM]. |
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V41067 | Oleana-2,12-dien-28-oic acid | 272108-04-0 | Oleana-2,12-dien-28-oic acid is an HBV (hepatitis B virus)-DNA inhibitor, HBsAg and HBeAg inhibitor. |
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V54178 | Oxynitidine | 548-31-2 | Oxynitidine is an HBV (hepatitis B virus) inhibitor (ID50=30.8 µg/mL), which can effectively inhibit the DNA replication activity of HBV (hepatitis B virus). |
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V54203 | Periglaucine B ((+)-Periglaucine B) | 1025023-05-5 | Periglaucine B ((+)-Periglaucine B) is an alkaloid and HBsAg inhibitor. |
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V54181 | Picroside IV (Picroside IV) | 211567-04-3 | Picroside IV is an iridoid glycoside derived from the underground parts of Coptidis rhizome. |
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V3656 | RG7834 S-isomer | 2072057-17-9 | RG7834 S-isomer, also known asRO 7020322 is the S-enantiomer of RG7834 (RO-7020322) which is a novel, potent and orally bioavailable inhibitor of HBV viral gene expression which blocks viral antigen and virion production. |
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V7268 | RO6889678 | 1578153-27-1 | RO6889678 (RO-6889678) is a novel and potent inhibitor of HBV, inhibitingHBV capsid formation. |
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V54182 | Sanggenol P | 1351931-30-0 | Sanggenol P is a flavonoid that has anti-HBV (hepatitis B virus) activity against HepG2.2.15 cell line in vitro. |
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V54198 | Schisanwilsonin C (Arisanschinin K) | 1181216-83-0 | Schisanwilsonin C (Arisanschinin K) has anti-HBV (hepatitis B virus) activity. |
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V35025 | Sophoranol (Sophoranol) | 3411-37-8 | Sophoranol is an alkaloid extracted from S. flavescens and has antiviral effect. |
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V54207 | Tiviciclovir (AM188) | 103024-93-7 | Tiviciclovir (AM188) is an antiviral guanosine analog and a hepatitis B virus inhibitor. |
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V54184 | TLR8 agonist 4 | 2761697-69-0 | TLR8 agonist 4 displays potent inhibitory effects on both wild-type and drug-resistant (lamivudine and entecavir) HBV (hepatitis B virus) strains. |
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V16597 | Torcitabine | 40093-94-5 | Torcitabine (2'-Deoxy-L-cytidine) is an antiviral active molecule. |
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V53363 | trans-ccc_R08 | 2413192-49-9 | trans-ccc_R08 (compound 1-B) is a potent cccDNA (covalently closed cyclic DMA) inhibitor. |
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V54211 | Tuvirumab (Tuvirumab; anti-hepatitis B; OST 577; SDZ-OST 577) | 138660-97-6 | Tuvirumab (OST 577; SDZ-OST 577) is a human IgG1 subclass monoclonal antibody (mAb) directed against HBV (hepatitis B virus) surface antigen (HBsAg). |
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V14774 | Vidarabine phosphate | 29984-33-6 | Vidarabine phosphate is an adenosine monophosphate analogue in which ribose is replaced by an arabinose moiety. |
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V54194 | Xalnesiran | 2538784-48-2 | Xalnesiran is an siRNA used to treat chronic HBV (hepatitis B virus). |
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