Hepatitis B virus, also known as HBV or Orthohepadnavirus, is a type of virus that belongs to the Hepadnaviridae family of viruses. Hepatitis B is brought on by the virus HBV. The ground squirrel hepatitis virus, the woodchuck hepatitis virus, and the woolly monkey hepatitis B virus are the other three species that make up the Orthohepadnavirus, of which the hepatitis B virus is the type species. The Hepadnaviridae family includes the genus as a member. Based on antigenic epitopes found on its envelope proteins, HBV is classified into four major serotypes (adr, adw, ayr, ayw), and eight genotypes (A-H) based on the genome's overall nucleotide sequence variation.The genotypes are used to track the evolution and spread of the virus because they have a distinct geographic distribution. The severity of the disease, the progression and propensity for complications, the response to treatment, and perhaps vaccination, are all impacted by genotype differences.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V54179 | HBV-IN-34 | 2716906-45-3 | HBV (hepatitis B virus)-IN-34 (compound 17i) is a potent inhibitor of HBsAg production. |
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V79441 | HBV-IN-35 | HBV (hepatitis B virus)-IN-35 (Compound 88) is an HBV (hepatitis B virus) inhibitor. | |
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V79710 | HBV-IN-36 | HBV (hepatitis B virus)-IN-36 (compound 42) is a potent HBV (hepatitis B virus) inhibitor (IC50=2 μM) with antiviral effect. | |
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V54204 | HBV-IN-37 | 380483-01-2 | HBV (hepatitis B virus)-IN-37 is an HBV (hepatitis B virus) inhibitor (antagonist) with EC50 of 10 μM. |
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V54210 | HBV-IN-38 | 1834483-86-1 | HBV (hepatitis B virus)-IN-38 (Example 193) is an HBV (hepatitis B virus) DNA inhibitor (EC50≤100nM). |
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V54200 | HBV-IN-39-d3 | 2173356-23-3 | HBV (hepatitis B virus)-IN-39-d3 (Example 14) is a deuterated form of HBV (hepatitis B virus)-IN-39 (Example 13). |
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V78340 | HBV-IN-40 | HBV (hepatitis B virus)-IN-40 (Compound 11826096) is an HBV (hepatitis B virus) inhibitor (IC50= 0.7 μM). | |
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V54183 | HBV-IN-41 | 1967002-25-0 | HBV (hepatitis B virus)-IN-41 (compound 45) is a potent orally bioactive HBV (hepatitis B virus) inhibitor (antagonist) with EC50 of 0.027μM. |
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V54197 | HBV-IN-6 | 2724224-47-7 | HBV (hepatitis B virus)-IN-6 is a potent HBV (hepatitis B virus) inhibitor (antagonist) with EC50 of 44 nM. |
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V54185 | HBV-IN-7 | 2724224-49-9 | HBV (hepatitis B virus)-IN-6 is a potent HBV (hepatitis B virus) inhibitor (antagonist) with EC50 of 5 nM. |
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V54175 | HBV-IN-8 | 2724224-57-9 | HBV (hepatitis B virus)-IN-6 is a potent HBV (hepatitis B virus) inhibitor (antagonist) with EC50 of 287.9 nM. |
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V54176 | HBV-IN-9 | 2170998-69-1 | HBV (hepatitis B virus)-IN-9 (example 20) is a potent HBsAg (HBV (hepatitis B virus) surface antigen) inhibitor (IC50=10 nM) and HBV (hepatitis B virus) DNA replication inhibitor (IC50=0.15 nM). |
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V54188 | Hepatitis B Virus Receptor Binding Fragment (hepatitis B peptide 4980) | 114495-85-1 | Hepatitis B Virus Receptor Binding Fragment (hepatitis B peptide 4980) is a synthetic peptide analog that specifically binds to Hep G2 cells. |
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V51949 | Inarigivir ammonium (ORI-9020 ammonium; SB-9000 ammonium) | 2172788-92-8 | Inarigivir (ORI-9020) ammonium is a dinucleotide antiviral compound that significantly reduces HBV (hepatitis B virus) DNA in transgenic mice expressing hepatitis B virus. |
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V29343 | Isoscopoletin | 776-86-3 | Isoscopoletin is a novel and potent bioactive compound. |
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V4501 | JNJ-632 | 1572510-42-9 | JNJ-632 is a novel and potent hepatitis B virus (HBV) capsid assembly modulator (CAM). |
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V54201 | Lagociclovir valactate | 1001670-19-4 | Lagociclovir valactate is the prodrug of Lagociclovir. |
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V51872 | Lenvervimab (GC1102) | 2055006-79-4 | Lenvervimab (GC1102) is an IgG1 recombinant human hepatitis B immunoglobulin. |
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V51860 | Libivirumab (17.1.41) | 569658-79-3 | Libivirumab (17.1.41) is a humanized anti-HBV (hepatitis B virus) monoclonal antibody (mAb). |
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V51847 | LPRP-Et-97543 | 84638-48-2 | LPRP-Et-97543 is a potent anti-HBV (hepatitis B virus) active molecule. |
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