HBV

HBV

Hepatitis B virus, also known as HBV or Orthohepadnavirus, is a type of virus that belongs to the Hepadnaviridae family of viruses. Hepatitis B is brought on by the virus HBV. The ground squirrel hepatitis virus, the woodchuck hepatitis virus, and the woolly monkey hepatitis B virus are the other three species that make up the Orthohepadnavirus, of which the hepatitis B virus is the type species. The Hepadnaviridae family includes the genus as a member. Based on antigenic epitopes found on its envelope proteins, HBV is classified into four major serotypes (adr, adw, ayr, ayw), and eight genotypes (A-H) based on the genome's overall nucleotide sequence variation.The genotypes are used to track the evolution and spread of the virus because they have a distinct geographic distribution. The severity of the disease, the progression and propensity for complications, the response to treatment, and perhaps vaccination, are all impacted by genotype differences.

HBV related products

Structure Cat No. Product Name CAS No. Product Description
V3511 Entecavir (SQ 34676) 142217-69-4 Entecavir (Baraclude;SQ34676 and BMS200475), anti-hepatitis B virus (HBV) agent,is a novel deoxyguanine nucleoside analogue and areverse transcriptase inhibitor.
V54190 Exbivirumab 569658-80-6 Exbivirumab is an anti-HBV (hepatitis B virus) monoclonal antibody (mAb).
V54174 Firzacorvir 2243747-96-6 Firzacorvir is a cyclic sulfonamide compound that modulates HBV (hepatitis B virus) core protein.
V54208 Glycosmisic acid 443908-19-8 Glycosmisic acid is a naturally occurring compound with anti-HBV (hepatitis B virus) activity.
V52028 GST-HG131 2270215-69-3 GST-HG131 is a specific HBV (hepatitis B virus) surface antigen inhibitor and belongs to the dihydrobenzopyridoxal (DBP) class of compounds.
V54195 HBV Seq1 aa:141-151 147318-53-4 HBV (hepatitis B virus) Seq1 aa:141-151 is a bioactive peptide.
V54196 HBV Seq1 aa:18-27 147820-47-1 HBV (hepatitis B virus) Seq1 aa:18-27 is the peptide fragment of HBV (hepatitis B virus) core antigen 18-27.
V54186 HBV Seq1 aa:63-71 189323-64-6 HBV (hepatitis B virus) Seq1 aa:63-71 is a fragment of HBV (hepatitis B virus).
V77804 HBV Seq1 aa:93-100 HBV (hepatitis B virus) Seq1 aa:93-100 is the peptide fragment of HBV (hepatitis B virus) core antigen 93-100.
V52011 HBV Seq2 aa:208-216 160214-63-1 HBV (hepatitis B virus) Seq2 aa:208-216 is an HBsAg-derived CD8 epitope peptide studied as part of the hepatitis B virus large envelope protein.
V52010 HBV Seq2 aa:28-39 168417-72-9 HBV (hepatitis B virus) Seq2 aa:28-39 is an HBsAg peptide that binds to major histocompatibility complex (MHC) class I molecules.
V54202 HBV-IN-10 2716907-16-1 HBV (hepatitis B virus)-IN-10 is an isomer of compound 6 (WO2021204258A1).
V54193 HBV-IN-11 2226178-41-0 HBV (hepatitis B virus)-IN-11 (Example 28) is a potent inhibitor of HBsAg secretion with EC50 of 0.46 µM (for details, check and find WO2018085619A1, example 28).
V54177 HBV-IN-12 2724229-06-3 HBV (hepatitis B virus)-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg) (0.001 μM< EC50 ≤0.05 μM).
V54205 HBV-IN-13 2724228-72-0 HBV (hepatitis B virus)-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg).
V52009 HBV-IN-29 2413192-59-1 HBV (hepatitis B virus)-IN-29 (ex8) is a flavonoid analogue and a potent inhibitor of covalently closed circular DNA (cccDNA).
V52008 HBV-IN-30 2413192-92-2 HBV (hepatitis B virus)-IN-30 (ex44) is a flavonoid analogue and a potent inhibitor of covalently closed circular DNA (cccDNA).
V52007 HBV-IN-31 2413192-95-5 HBV (hepatitis B virus)-IN-31 is a potent inhibitor of covalently closed circular DNA (cccDNA).
V52006 HBV-IN-32 2413193-04-9 HBV (hepatitis B virus)-IN-31 is a potent inhibitor of covalently closed circular DNA (cccDNA).
V79034 HBV-IN-33 HBV (hepatitis B virus)-IN-33 (C-49) is an inhibitor (blocker/antagonist) of HBV (hepatitis B virus) and significantly inhibits HBV (hepatitis B virus) replication in HepAD38, HepG2-HBV (hepatitis B virus)1.3 and HepG2-NTCP cells.
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